Abraxane lyophilizate 100mg, 1pc

Abraxane: What Is It?

Abraxane, sometimes referred to as paclitaxel protein-bound particles for injectable solution, is a powerful cancer treatment used in the treatment of several kinds of tumors. It is a form of paclitaxel, a chemotherapeutic agent known for combating certain cancer cells.

Abraxane distinguishes itself through its unique composition, which combines naturally existing proteins present in the human body—binding paclitaxel to albumin. This formulation minimizes side effects and increases efficacy by delivering the medication more effectively to cancer cells.

What is Abraxane?

Abraxane is composed of human albumin combined with paclitaxel, a cytotoxic antineoplastic drug. This lyophilized, sterile powder must be reconstituted before use. Each single-use vial contains approximately 900 mg of human albumin and 100 mg of paclitaxel.

Advantages and Results of Abraxane

Abraxane is chosen by various cancer patients due to its advantages over conventional paclitaxel formulations:

• Targeted Delivery: Abraxanes albumin-bound particles ensure more focused paclitaxel delivery to cancer cells, reducing the impact on healthy tissues. This minimizes negative effects and increases therapeutic effectiveness.
• Faster Infusion Time: Abraxane is more patient-friendly than conventional paclitaxel, as it can be administered over a shorter duration.
• No Premedication Required: Unlike some chemotherapy medications, Abraxane typically does not require premedication to prevent allergic reactions.

Reduced side effects and shorter infusion times contribute to an improved quality of life for patients undergoing Abraxane treatment.

Uses of Abraxane

Abraxane is indicated for the treatment of various forms of malignancies, including:

• Metastatic Breast Cancer: Patients with metastatic breast cancer, especially those who have not responded to prior treatments, often choose Abraxane as their course of treatment.
• Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC): Abraxane treats advanced or metastatic NSCLC in combination with other chemotherapy medications.
• Advanced or Metastatic Pancreatic Cancer: Abraxane is also used in combination with other chemotherapy medications to treat advanced or metastatic pancreatic cancer.

Dosage and Administration

Abraxane is administered intravenously, meaning it is injected directly into a vein. The recommended dosage and frequency of administration depend on the type of malignancy being treated and the individual patients health status.

The recommended dosage is 100 mg/m2, given as an intravenous infusion over 30 minutes. The frequency of administration is determined by the specific cancer being treated. Typically, Abraxane is given on Days 1, 8, and 15 of a 21-day cycle. However, it is crucial to follow your doctors instructions closely.

Side Effects of Abraxane

While not everyone experiences them, the side effects of Abraxane are similar to those of all chemotherapy medications.

• Nausea and Vomiting: These are common adverse effects of chemotherapy, but there are medications available to help control them.
• Reduced Blood Cell Production: Abraxane can reduce blood cell synthesis, leading to lower white blood cell counts and increased susceptibility to infection.
• Fatigue or Weakness: Another common side effect of chemotherapy is fatigue or weakness.
• Hair Loss: Abraxane can lead to typically temporary hair loss.
• Peripheral Neuropathy: This can cause numbness, tingling, or discomfort in the hands and feet by affecting the nerves in these areas.

Report any side effects to your doctor so they can be managed appropriately.

Contraindications for Abraxane

Abraxane is not suitable for everyone, and contraindications exist. Patients known to be hypersensitive to paclitaxel or any other component in the formulation should avoid it. Patients with severe liver damage or significant bone marrow suppression should also avoid Abraxane.

Storage of Abraxane

Abraxane should be stored at controlled room temperature between 20°C and 25°C (68°F and 77°F). Protect it from moisture and light. Keep it out of reach of children.

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