Aescusan, drops for oral use, 20ml

Composition

100 g of oral solution contains:

Active ingredients:

horse chestnut seed extract dry (Hippocastani extractum siccum normatum) 5-7: 1 4.725 g (extractant-ethanol 60% v / v), thiamine hydrochloride 0.5 g,

Auxiliary substances:

ethanol 96% — 26.4 g;

purified water-67.675 g;

lactose monohydrate-0.432 g;

colloidal silicon dioxide-0.243

Pharmacological action

Escuzan is a herbal medicine used for venous circulatory disorders.

It has an anti-exudative and venotonizing effect. It was found that horse chestnut seed extract reduces the concentration of lysosomal enzymes, which reduces the breakdown of mucopolysaccharides in the capillary walls.

Escuzan reduces vascular permeability by preventing filtration of low-molecular-weight proteins, electrolytes, and water into the intercellular space.

Indications

Chronic venous insufficiency of class I–III according to CEAR classification: varicose veins, edema, cramps in the calf muscles, a feeling of heaviness in the legs.

Contraindications

• hypersensitivity to the components of the drug Escuzan;
• liver diseases;
• lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
• children (up to 12 years).

With caution: alcoholism; traumatic brain injury; brain diseases; children’s age (over 12 years).

Side effects

• Possible allergic reactions,
• irritation of the gastrointestinal mucosa,
• headaches,
• dizziness.

Interaction

The effect of thiamine decreases when used simultaneously with sulfite-containing infusion solutions.

Fluorouracil, vinblastine, bleomycin, cisplatin interfere with the absorption of vitamin B1. Penicillamine, isoniazid reduce the effectiveness of vitamin B1, increasing its excretion.

How to take, course of use and dosage

Inside, before eating. Before use, dilute in a small amount of water.

Take 12-15 drops 3 times a day. The duration of therapy is determined by the attending physician. Shake thoroughly before use.

Overdose

Symptoms: there may be a feeling of heaviness in the epigastric region.

Treatment: symptomatic. The drug should be discontinued.

Special instructions

The drug Escuzan contains 31% ethanol. If the recommended dosages are observed, up to 0.128 g of ethanol enters the body at each dose of the drug, and the maximum daily dose of the drug contains up to 0.384 g of ethanol.

During long-term storage of medicinal products (liquid dosage forms) based on medicinal plant raw materials, turbidity of the solution and precipitation may occur, which does not affect the quality of the drug.

Influence on the ability to drive vehicles and work with mechanisms.

During the period of using the drug, care should be taken when performing potentially dangerous activities that require increased attention and speed of psychomotor reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator).

Form of production

Solution for oral use

Storage conditions

At a temperature of 8-25 °C

Shelf life

3 years

Active ingredient

Thiamine, Escin

Dosage form

Drops for oral use

Description

For adults, Children over 12 years of age

Indications

Hemorrhoids, Varicose Veins