Composition
Active ingredients:
Glucosamine Hydrochloride 500 mg
Chondroitin Sodium Sulfate 500 mg
Auxiliary substances:
two-substituted calcium phosphate,
microcrystalline cellulose,
sodium croscarmellose, stearic acid,
magnesium stearate.
Shell:
Hydroxypropyl methylcellulose, titanium dioxide (E 171), triacetin.
Pharmacological action
Stimulator of cartilage tissue regeneration.
Glucosamine and chondroitin sulfate sodium take part in the biosynthesis of connective tissue, helping to prevent the destruction of cartilage, stimulating tissue regeneration. The introduction of exogenous glucosamine enhances the production of the cartilage matrix and provides non-specific protection, including from NSAIDs and corticosteroids. The drug has a moderate anti-inflammatory effect.
Chondroitin sulfate sodium, regardless of whether it is absorbed in intact form or in the form of individual components, serves as an additional substrate for the formation of a healthy cartilage matrix.
It stimulates the formation of proteoglycans and type II collagen, and also protects the cartilage matrix from enzymatic cleavage (by suppressing the activity of hyaluronidase) and from the damaging effects of free radicals; it supports the viscosity of synovial fluid, stimulates cartilage repair mechanisms, and suppresses the activity of those enzymes (elastase, hyaluronidase) that break down cartilage. When treating osteoarthritis, it eases the symptoms of the disease and reduces the need for NSAIDs.
Indications
Osteoarthritis of the peripheral joints and spine.
Use during pregnancy and lactation
It is not recommended to use during pregnancy and lactation.
Contraindications
Hypersensitivity, severe renal impairment.
With caution: Â bleeding or a tendency to bleed, bronchial asthma, diabetes mellitus.
Side effects
Glucosamine: possible mild gastrointestinal disorders (epigastric pain, flatulence, diarrhea, constipation), dizziness, allergic skin reactions. Chondroitin: Â allergic reactions.
Interaction
Increases the absorption of tetracyclines, reduces the effect of semi-synthetic penicillins. The drug is compatible with NSAIDs and corticosteroids.
How to take, course of use and dosage
Inside.
Adults and children over 15 years of age: 1 tablet of Artra 2 times a day for the first three weeks; 1 tablet 1 time a day for the following weeks and months. A stable therapeutic effect is achieved when taking the drug for at least 6 months.
Overdose
Symptoms: Overdose cases are unknown.
Treatment: gastric lavage, symptomatic therapy.
Form of production
Biconvex tablets of oval shape, covered with a film-coated white to white with a yellowish tinge of color, with inclusions, with the inscription “ARTRA” on one side, with a specific smell.
Storage conditions
at a temperature of 10-30°C, in a dry place.
Active ingredient
Glucosamine, Chondroitin Sulfate
Dosage form
Tablets
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