Asparcam Renewal pills, 24pcs

Composition

Asparcam-0.5 g active substances: potassium asparaginate hemihydrate – – 0.177 gmagnesium asparaginate tetrahydrate – 0.177 gwsomogatelnye substances: potato starch-0.131 g zinc-0.010 g calcium stearate-0.005 g

Pharmacological action

Asparcam is a source of potassium and magnesium ions, regulates metabolic processes, helps restore electrolyte balance, and has an antiarrhythmic effect.

Potassium ion is involved in conducting impulses along nerve fibers, as well as in synaptic transmission, performing muscle contractions, and maintaining normal heart activity. Violation of the exchange of potassium ions leads to a change in the excitability of nerves and muscles.

Active ion transport maintains a high gradient of potassium ions across the plasma membrane. In small doses, potassium ion dilates the coronary arteries, in large doses – narrows. It has a negative chrono-and bathmotropic effect, in high doses – negative ino – and dromotropic, as well as moderate diuretic effect.

Magnesium ion is a cofactor of 300 enzyme reactions. An irreplaceable element in processes that ensure the supply and consumption of energy. It is involved in electrolyte balance, ion transport, membrane permeability, and neuromuscular excitability.

It is part of the structure (pentose phosphate) of deoxyribonucleic acid. Participates in the synthesis of ribonucleic acid, the apparatus of heredity, cell growth, in the process of cell division. Limits and prevents excessive catecholamine release under stress, lipolysis and free fatty acid release are possible. It is a “physiological” blocker of slow calcium channels. Promotes the penetration of potassium ion into cells.

Asparaginate promotes the penetration of potassium and magnesium ions into the intracellular space, stimulates intercellular phosphate synthesis.

Pharmacokinetics

It is easily absorbed when taken orally and is relatively quickly excreted in the urine.

Indications

Asparcam is used in complex therapy for heart failure, coronary heart disease, hypokalemia, cardiac arrhythmias (including myocardial infarction, overdose of cardiac glycosides).

Use during pregnancy and lactation

Application is possible if the potential benefit to the mother outweighs the potential risk to the fetus or child.

Contraindications

Hypersensitivity to the drug, impaired amino acid metabolism, hypotension, acute and chronic renal failure, hyperkalemia, hypermagnesemia, impaired atrioventricular conduction (atrioventricular block of I-III degrees), severe myasthenia gravis, hemolysis, adrenal cortical insufficiency, age up to 18 years (efficacy and safety have not been established).

With caution prescribed during pregnancy and during breastfeeding, lactation.

Side effects

Possible nausea, vomiting, diarrhea, unpleasant sensations or burning in the epigastric region (in patients with anacid gastritis or cholecystitis), hyperkalemia (nausea, vomiting, diarrhea, parastesias), hypermagnesemia (redness of the face, thirst, decreased blood pressure, hyporeflexia, muscle weakness, paresis, coma, areflexia, respiratory depression, convulsions).

Composition

Pharmacodynamic interactions: concomitant use with potassium-sparing diuretics (triamterene, spironolactone), beta-blockers, cyclosporine, heparin, angiotensin-converting enzyme inhibitors, and nonsteroidal anti-inflammatory drugs increases the risk of hyperkalemia up to the development of arrhythmia and asystole. The use of potassium preparations together with glucocorticosteroids eliminates hypokalemia caused by the latter.

Due to the content of potassium ions, the undesirable effects of cardiac glycosides are reduced.

Due to the content of magnesium ions, it reduces the effect of neomycin, polymyxin B, tetracycline and streptomycin.

When used concomitantly, the drug may increase neuromuscular blockade caused by depolarizing muscle relaxants (atracurium bezilate, decamethonium bromide, suxamethonium (chloride, bromide, iodide)).

Calcitriol increases the content of magnesium ions in the blood plasma; calcium preparations reduce the effect of magnesium preparations.

Pharmacokinetic: astringents and enveloping agents reduce the absorption of the drug in the gastrointestinal tract.

How to take, course of use and dosage

Asparcamprin inside after eating 1-2 tablets 3 times a day. The course of treatment is 3-4 weeks. If necessary, repeat the course.

Overdose

Symptoms: conduction disorders (especially with previous pathology of the cardiac conduction system).

Treatment: intravenous use of calcium chloride; if necessary, hemodialysis and peritoneal dialysis.

Special instructions

In case of cardiac arrhythmias in combination with atrioventricular block, the use of Asparcam is not recommended.

Information about the possible effect of a medicinal product for medical use on the ability to drive vehicles and mechanisms

No information available.

Storage conditions

At a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf

life is 3 years.

Active ingredient

Potassium asparaginate, Magnesium asparaginate

Dosage form

Tablets

Indications

Improve your Cardiovascular System