ATC code | L04AA12 |
---|---|
CAS Number | 276648-80-0 |
Other product names | Belimumab |
Dosage form | Lyophilizate for concentrate for solution for infusion |
Active ingredient | Belimumab |
Other ingredients | None |
Pharmacological classification | B-lymphocyte stimulator (BLyS)-specific inhibitor |
Pharmacological action | Inhibits the survival of B cells, prevents BLyS from stimulating the growth of B cells |
Storage conditions | Refrigerate vials at 36F to 46F (2C to 8C) |
Benlysta: A Treatment for Systemic Lupus Erythematosus (SLE)
Benlysta (belimumab) is a prescription medication used to treat adults with active, autoantibody-positive systemic lupus erythematosus (SLE). It is sometimes used in conjunction with conventional treatment.
Understanding SLE and Benlysta’s Role
Imagine your immune system as a team of superheroes, but they are overly enthusiastic and attack your healthy cells. SLE is like a renegade superhero squad that needs help getting back on track. Benlysta intervenes to calm things down, helping to reduce inflammation and damage that SLE can cause.
Benlysta’s Composition
As a monoclonal antibody, Benlysta is a specially designed protein that targets a specific part of the immune system. In this case, Benlysta specifically targets BLyS, a protein that supports the growth and development of white blood cells, or B cells. By blocking BLyS, Benlysta helps control the immune system and reduce the overactivity that causes SLE symptoms.
Benefits and Considerations
Benlysta can:
- Reduce lupus disease activity
- Decrease your chances of severe lupus flares
- Reduce symptoms, including fatigue, joint pain, and muscle soreness, to improve your quality of life.
While Benlysta can help manage symptoms and improve your overall well-being, it is not a cure for SLE. Talk to your doctor about your treatment plan to determine if Benlysta is right for you.
Uses of Benlysta
Benlysta is used to treat two specific conditions related to SLE:
- Systemic Lupus Erythematosus (SLE): This chronic autoimmune disease affects multiple areas of the body, including the skin, joints, kidneys, and heart.
- Lupus Nephritis: This is a specific type of kidney inflammation caused by SLE. Benlysta helps reduce inflammation in the kidneys and prevent further damage.
Benlysta Administration
Benlysta is administered under medical supervision as an intravenous infusion (IV). The frequency and dosage of infusions will be determined by your doctor based on your individual needs.
Dosage and Administration
The recommended dosage of Benlysta is 10 mg/kg given every two weeks for the first three doses and then every four weeks thereafter. It is crucial to take the medication exactly as directed and follow your doctors instructions closely.
Potential Side Effects
Like most medications, Benlysta can have side effects. Some common side effects include:
- Feeling unwell
- Shortness of breath
- Fever
- Nasopharyngitis (inflammation of the nose and throat)
- Lung inflammation
- Sleep problems
- Pain
- Depression
- Migraine
- Pharyngitis (inflammation of the throat)
- Injection site reactions (if receiving subcutaneous injections)
While less common, serious side effects can occur. These may include:
- Serious infections
- Progressive multifocal leukoencephalopathy (PML)
- Anaphylaxis (a severe allergic reaction)
- Anxiety and suicidality
- Increased risk of cancer
If you experience any side effects, especially severe ones, contact your doctor immediately.
Contraindications
Benlysta is not suitable for everyone. Inform your doctor about any medical conditions you have, including:
- Previous anaphylaxis to Benlysta
- Acute or chronic infections
- Current SLE treatment with Rituximab
- If you are breastfeeding or pregnant
Storage
Store Benlysta in the refrigerator between 2°C and 8°C (36°F and 46°F). Protect it from direct sunlight and heat.
Important Considerations
- Benlysta can help manage symptoms and improve your quality of life, but it is not a cure for SLE.
- Talk to your doctor about your treatment plan to determine if Benlysta is right for you.
- Always take the medication exactly as directed by your doctor and follow their instructions closely.
- See your doctor immediately if you experience any side effects, particularly severe ones.
Order Benlysta Online
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Benlysta: Order Now – Effective Lupus Treatment!
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