ATC code | A02BX01 |
---|---|
CAS Number | 1306-86-3 |
Other product names | De-Nol, Gastrodenol, Bismuthi Tripotassium Dicitrate |
Dosage form | Film-coated tablet |
Active ingredient | Tripotassium dicitratobismuthate |
Other ingredients | Corn starch, povidone K-30, potassium polyacrylin, macrogol 6000, magnesium stearate, polyvinyl alcohol, macrogol 4000, talc, titanium dioxide |
Pharmacological classification | Gastroprotective and antiulcer agent |
Pharmacological action | Gastroprotective, antiulcer, bactericidal against Helicobacter pylori, anti-inflammatory, astringent |
Storage conditions | Store below 25°C |
Bismuthi Tripotassium Dicitrate: What Is It?
Bismuthi tripotassium dicitrate, also known as bismuth subcitrate potassium, is a medication used to treat several gastrointestinal disorders. Its primary uses include:
- Treating gastritis
- Treating peptic ulcers
- Treating GERD (gastric reflux disease)
- Removing the bacterium Helicobacter pylori, a common cause of ulcers, in conjunction with other medications.
Bismuthi Tripotassium Dicitrate Composition
Each pill of bismuth tripotassium dicitrate contains 303.03 mg of the active ingredient, equivalent to 120 mg of bismuth oxide. Other inactive components include:
- Maize starch
- Povidone K-30
- Potassium polyacrylin
- Macrogol 6000
- Magnesium stearate
- Opadry II clear (comprising polyvinyl alcohol, macrogol 4000, talc, and titanium dioxide)
Benefits and Effects of Dicitrate Bismuthi Tripotassium
Bismuthi tripotassium dicitrate works by forming a protective layer over the lining of the stomach and duodenum. This layer helps to prevent further damage from stomach acids and digestive enzymes. It also possesses antimicrobial properties, particularly against Helicobacter pylori.
Here are some primary benefits of using bismuth tripotassium dicitrate:
- Treats ulcers: By protecting the damaged stomach lining from further irritation, bismuth tripotassium dicitrate helps ulcers to heal.
- Lowers inflammation: Its effectiveness in eradicating Helicobacter pylori, a common cause of ulcers and gastritis, helps to reduce inflammation in the stomach and intestines.
- Relieves symptoms: Bismuthi tripotassium dicitrate can provide relief from heartburn, nausea, and indigestion, among other conditions.
What Are the Uses of Dicitrate Bismuthi Tripotassium?
Common uses for bismuth tripotassium dicitrate include:
- Treating peptic ulcers: It is sometimes used in combination with antibiotics to treat peptic ulcers caused by Helicobacter pylori.
- Treating gastritis: It can help to reduce inflammation and heal the stomach lining in cases of gastritis.
- Treating GERD: It can help to reduce acid reflux and other symptoms associated with GERD.
- Preventing travelers diarrhea: While not as commonly used for this purpose, some people use bismuth tripotassium dicitrate to prevent travelers diarrhea.
How Should One Use Bismuthi Tripotassium Dicitrate?
Always take bismuth tripotassium dicitrate according to the directions given by your pharmacist or doctor. The dosage and duration of treatment will depend on your specific condition.
Bismuthi tripotassium dicitrate is typically taken orally. It is usually taken 30 minutes before meals and at bedtime, and should be swallowed whole with a glass of water.
Dosage and Method of Administration
Adults typically take one tablet four times a day. However, your doctor may adjust the dosage based on your individual needs. It is important to follow your prescription exactly and avoid exceeding the recommended dosage.
Side Effects
Like any medication, bismuth tripotassium dicitrate may have side effects in some people. Common side effects include:
- Diarrhea or constipation
- Nausea
- Headache
- Black or dark tongue: This is usually harmless and will go away once you stop taking the medication.
- Dark stools: This is also harmless and usually goes away once you stop taking the medication.
These side effects are usually mild and should go away on their own. However, you should see your doctor if you experience any severe or persistent side effects.
Contraindications
Not everyone can benefit from bismuth tripotassium dicitrate. Before starting this medication, be sure your doctor knows if you have any of the following conditions:
- Kidney disease: People with kidney disease should avoid bismuth tripotassium dicitrate.
- Liver disease: Bismuthi tripotassium dicitrate can cause damage to people with liver disease.
- Bismuthi allergy: You should not use this medication if you have a bismuth allergy.
- Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks.
- Breastfeeding: This medication should not be used during breastfeeding unless the benefits outweigh the risks.
Storage Conditions
Store bismuth tripotassium dicitrate at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.
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