ATC code | L01EX07 |
---|---|
CAS Number | 394881-00-0 |
Other product names | Cabozantinib, Cometriq, Aptimetyx |
Dosage form | Film-coated tablets |
Active ingredient | Cabozantinib |
Other ingredients | Cabozantinib (S)-malate, lactose monohydrate, microcrystalline cellulose, crospovidone, sodium starch glycolate, magnesium stearate, hypromellose, titanium dioxide, macrogol, iron oxide yellow, iron oxide red |
Pharmacological classification | Antineoplastic agent, tyrosine kinase inhibitor |
Pharmacological action | Inhibits the activity of multiple tyrosine kinases, including MET, VEGFR2, and RET, thereby blocking signals that allow cancer cells to grow and divide, and also helps to block the growth of new blood vessels in the area of the tumor |
Storage conditions | Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) |
What is Cabometyx?
Cabometyx, or cabozantinib, is a medication used to treat certain types of cancer. It works as a kinase inhibitor, blocking the activity of enzymes that help cancer cells grow and spread.
Cabometix Composition
Each Cabometix tablet contains 40 mg of cabozantinib. The drug is designed for once-daily use.
Benefits and Uses of Cabometyx
Cabometix can help stop certain cancers from spreading and growing. It has shown benefit in treating:
- Advanced renal cell carcinoma (RCC) in individuals who have undergone past anti-angiogenic treatment.
- First-line therapy advanced RCC combined with nivolumab.
- Hepatocellular carcinoma (HCC) in patients having past sorafenib treatment.
- Localized advanced or metastatic differentiated thyroid cancer (DTC).
How to Take Cabometyx
Cabometix pills are for oral use only. They should be swallowed whole with a full glass of water and not crushed. Take Cabometix exactly as directed by your doctor. The appropriate dosage will depend on your medical history and individual needs.
Dosage and Administration
The recommended starting dose of Cabometix is 40 mg once daily. However, your doctor may adjust your dosage based on your response to treatment and any side effects you experience. Pay close attention to your doctors recommendations regarding the amount and frequency of administration.
Possible Side Effects
Like all medications, Cabometix can have side effects. Some common side effects include:
- Diarrhea
- Fatigue
- Loss of appetite
- Vomiting
- High blood pressure
- Hand-foot syndrome (redness, swelling, and pain in the palms of the hands and soles of the feet)
More serious side effects can also occur, including:
- Low red blood cell count (anemia)
- Heart problems
- Liver problems
- Kidney problems
- Blood clots
If you experience any side effects, tell your doctor immediately. They can help manage any adverse effects and determine if the benefits of taking Cabometix outweigh the risks.
When to Avoid Cabometyx
Cabometix is not suitable for everyone. It is contraindicated in individuals with certain medical conditions, including:
- Severe liver disease
- Severe kidney disease
- Active bleeding
- A history of a severe allergic reaction to any component of cabozantinib or its formulations
Before starting Cabometyx, be sure to discuss any of these conditions with your doctor. They can determine whether Cabometix is safe for you.
Important Considerations
Remember, Cabometix is a powerful medication and should only be taken under the guidance of a licensed medical professional. Always follow your doctors instructions carefully and address any questions or concerns you may have. Tell your doctor if you have any pre-existing medical conditions before starting Cabometyx.
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