ATC code | L01XA02 |
---|---|
CAS Number | 41575-94-4 |
Other product names | Paraplatin |
Dosage form | Concentrate for solution for infusion |
Active ingredient | Carboplatin |
Other ingredients | Water for injections |
Pharmacological classification | Antineoplastic agent |
Pharmacological action | Cytotoxic, DNA alkylating agent |
Storage conditions | Store in a refrigerator (2°C to 8°C). Protect from light. Do not freeze. |
Carboplatin-RONC Concentrate 10 mg/mL, 15 mL, 1 pc
Used in treatment of some forms of cancer, carboplatin-RONC Concentrate 10 mg/mL, 15 mL, 1 pc is a chemotherapeutic drug. It is a member of a class of medications known as alkylating agents, which destroy cancer cells DNA, stopping their growth and multiplication. This drug is sold as a concentrate for injection; hence, it must be diluted with a suitable liquid before being given intravenously.
Carboplatin-RONC Concentrate Composition
Carboplatin-RONC Concentrate has 10 mg of carboplatin per milliliter. There were 150 mg of carboplatin in the 15-ml vial overall. This is a clear, colorless to faintly yellow solution.
Carboplatin-RONC Concentrate Benefits and Effects
Powerful chemotherapeutic agent carboplatin-RONC concentrate can treat several forms of cancer, including:
- advanced ovarian cancer of epithelial origin, especially in second-line therapy following prior treatments failing.
- Adjuvant treatment for high-risk seminoma (stage I) testicular germ cell tumors
- Lung small cell cancer.
The type and stage of cancer, the patients general condition, and the particular treatment plan all affect how well carboplatin works. See a skilled oncologist to ascertain whether carboplatin is the best course of action for you.
Carboplatin-RONC Concentrate Uses
Lung cancer, testicular cancer, and ovarian cancer, among other forms of cancer, are treated with carboplatin. Usually used either as a single agent or in concert with other chemotherapy medications, the type and stage of cancer being treated as well as the individual patients health state will determine the particular dosage and frequency of administration.
How to Use Carboplatin-RONC Concentrate
An intravenous healthcare practitioner administers carboplatin-RONC concentrate. Usually, it is infused over fifteen to sixty minutes. The doctor decides the quantity and frequency of administration depending on the patients particular requirements and the particular cancer under treatment.
Carboplatin-RONC Concentrate Dosage and Administration
For previously untreated people with normal renal function, the advised dosage of carboplatin is 400 mg/m2 given as a single dose over 15 to 60 minutes. Alternatively, the dosage can be computed with the Calvert formula:
Dose (mg) = GFR ml/min / 25 Target AUC (mg/ml x min).
The Calvert formula computes the overall dosage in mg rather than mg/m2.
Renal function of the patient should guide dosage adjustment. Patients with weak renal ability could need a smaller dosage to prevent significant myelosuppression. Usually every four weeks, the frequency of therapy varies based on the response of the particular patient to it.
Carboplatin-RONC Concentrate Side Effects
Carboplatin has negative effects, just like most chemotherapy medications. The most often occurring adverse effects consist of:
- Vigues of nausea and vomiting
- Hairstyling loss
- Low blood cell counts—neutropenia, anemia, thrombocytopenia—
- weariness
- Mouth ulcers
- diarrhea
- Deaf Hearing Loss
- Problems with kidneys
Some side effects could be really severe and require medical intervention. You should immediately see your doctor if you have any unusual or recurring side effects.
Carboplatin-RONC Concentrate Contraindications
In the following circumstances, carboplatin is contraindicated:
- Hypersensitivity to any of the excipients indicated in the product description, other platinum-containing compounds, or carboplatin.
- Extreme myelosuppression.
- Pre-existing severe renal impairment (with creatinine clearance less than 30 ml/min) unless the possible advantages of treatment exceed the hazards.
- concurrent usage with the vaccination against yellow fever.
Before beginning carboplatin treatment, be sure your doctor is aware of any pre-existing medical issues, allergies, or medications you are taking.
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