Composition
1 capsule contains:
Active ingredient:
choline alfoscerate in terms of 100% substance-400 mg;
excipients:
glycerol,
purified water;
capsule composition:
gelatin,
sorbitol,
glycerol,
methyl parahydroxybenzoate,
propyl parahydroxybenzoate,
titanium dioxide,
iron oxide yellow dye,
purified water.
Pharmacological action
Pharmacodynamics
Cereton is a nootropic agent. Central cholinostimulator, which contains 40.5% of metabolically protected choline. Metabolic protection promotes the release of choline in the brain.
Provides synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the central nervous system, activates the reticular formation.
Increases the linear velocity of blood flow on the side of traumatic brain damage, contributes to the normalization of spatiotemporal characteristics: spontaneous bioelectric activity of the brain, regression of focal neurological symptoms and restoration of consciousness; has a positive effect on the cognitive and behavioral responses of patients with vascular diseases of the brain (dyscirculatory encephalopathy and residual phenomena of cerebral circulatory disorders).
It has a preventive and corrective effect on pathogenetic factors of involutional psychoorganic syndrome, changes the phospholipid composition of neuronal membranes: it participates in the synthesis of phosphatidylcholine (membrane phospholipid), improves the plasticity of neuronal membranes. It stimulates the dose-dependent release of acetylcholine under physiological conditions, improves synaptic transmission, and receptor function. It does not affect the reproductive cycle and has no teratogenic, mutagenic effect.
Pharmacokinetics
Easily penetrates the blood-brain barrier,85% is excreted by the lungs in the form of carbon dioxide, the remaining amount (15%) is excreted by the kidneys and through the intestines.
Indications
- the recovery period, traumatic brain injury and ischemic stroke, the recovery period of hemorrhagic stroke, occurring with a focal hemispheric symptoms or symptoms of lesions of the brain stem;
- psycho-organic syndrome on the background of involution and degenerative changes in the brain;
- cognitive disorders (disorders of mental function, memory, confusion, disorientation, decreased motivation, initiative and ability to focus), including dementia and encephalopathy;
- senile pseudomalachite.
Use during pregnancy and lactation
The use of the drug Tsereton during pregnancy and lactation is contraindicated.
Breast-feeding should be discontinued during treatment with Cereton.
Contraindications
- hypersensitivity to the drug;
- acute stage of hemorrhagic stroke;
- pregnancy; breast-feeding period;
- children under 18 years of age (due to lack of data).
Side effects
Nausea may occur (mainly as a result of dopaminergic activation), in this case, the dose of the drug is reduced.
Allergic reactions.
How to take, course of use and dosage
In the recovery period of traumatic brain injury, ischemic or hemorrhagic stroke, Tsereton is prescribed 800 mg in the morning and 400 mg in the afternoon for 6 months.
In patients with chronic cerebrovascular insufficiency and dementia syndromes, Tsereton is prescribed 400 mg (1 capsule) 3 times a day, preferably after meals, for 3-6 months.
Overdose
Nausea may occur.
Treatment: symptomatic therapy.
Special instructions
Ceretone does not affect the speed of psychomotor reactions.
Form of production
Capsules
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25 °C
Shelf life
3 years
Active ingredient
Choline alfoscerate
Conditions of release from pharmacies
By prescription
Dosage form
Capsules
Description
For adults as directed by your doctor
Indications
Acquired Dementia, Cerebral Circulation Disorders, Mental Disorders, Alzheimer’s Disease, Stroke Effects
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Side effects of Cereton, 400mg capsules, 28pcs.
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