ATC code | C09DA04 |
---|---|
CAS Number | 138336-55-2 (Irbesartan) and 58-93-5 (Hydrochlorothiazide) |
Other product names | Aprovel, Irbesartan/Hydrochlorothiazide |
Dosage form | Film-coated tablets |
Active ingredient | Irbesartan and Hydrochlorothiazide |
Other ingredients | Microcrystalline cellulose, crospovidone, sodium stearyl fumarate, hypromellose, titanium dioxide (E171), macrogol 400, talc, iron oxide red (E172), iron oxide yellow (E172) |
Pharmacological classification | Angiotensin II receptor antagonist and Thiazide diuretic |
Pharmacological action | Lowering blood pressure |
Storage conditions | Store below 25°C, in the original package |
Coaprovel 25 mg+300 mg: What is it?
Coaprovel 25 mg+300 mg is a prescription medicine that combines two potent blood pressure-lowering medications—hydrochlorothiazide, a thiazide diuretic, and irbesartan, an angiotensin II receptor blocker.
Its used to treat high blood pressure, or hypertension, when therapy with either irbesartan or hydrochlorothiazide alone hasnt been successful.
What is Coaprovel 25 mg+300 mg?
Every Coaprovel 25 mg+300 mg tablet contains 25 mg of hydrochlorothiazide and 300 mg of irbesartan. It comes in blister packs of 28 tablets.
How does Coaprovel 25 mg+300 mg work?
Coaprovel lowers blood pressure in two ways:
- Irbesartan reduces the effect of angiotensin II, a hormone that narrows blood vessels. By blocking angiotensin II, irbesartan helps to enlarge blood vessels, facilitating blood flow and reducing blood pressure.
- Hydrochlorothiazide, a diuretic, helps your body eliminate extra salt and moisture. This reduces your bodys blood volume, also lowering blood pressure.
What is Coaprovel 25 mg+300 mg used for?
Coaprovel is used to treat hypertension—high blood pressure. High blood pressure is a common condition that can lead to serious health issues like kidney failure, stroke, and heart attack.
Coaprovel is sometimes recommended when someone needs to take multiple medications to control their blood pressure or when other medications havent been effective.
How to use Coaprovel 25 mg+300 mg
Coaprovel tablets are usually taken once a day, either with or without food. Your doctor will determine the appropriate dosage for you based on your medical history and individual needs.
Its crucial to take Coaprovel exactly as directed and follow your doctors instructions closely.
Coaprovel 25 mg+300 mg Dosage and Administration
Coaprovel typically starts at a dosage of 150 mg/12.5 mg once a day. The dosage may be increased after one to two weeks to a maximum of one 300 mg/25 mg tablet once a day, depending on your blood pressure response.
Doses higher than 300 mg irbesartan/25 mg hydrochlorothiazide once a day are not recommended.
Side Effects of Coaprovel 25 mg+300 mg
Like all medications, Coaprovel can cause side effects. The most common side effects include:
- Dizziness
- Nausea
- Fatigue (tiredness)
- Unusual urination
- Elevated blood urea nitrogen (BUN)
- Lower creatinine
- Increased creatine kinase
If you experience any of these side effects or any others, consult your doctor.
Coaprovel 25 mg + 300 mg: Who shouldn’t take it?
You should not take Coaprovel if:
- You are allergic to irbesartan, hydrochlorothiazide, or other sulfonamide-derived medications.
- You are more than three months pregnant; its best to avoid Coaprovel during early pregnancy.
Important Considerations
Inform your doctor about all medications you take, including over-the-counter drugs and vitamins, as Coaprovel may interact with them.
Also, tell your doctor about any medical conditions you have, including diabetes, liver disease, or kidney disease. Your doctor may need to adjust your dosage or monitor you more closely if you have any of these conditions.
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