Elcar oral solution 300mg/ml vial, 50ml

Composition

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1 ml of the oral solution contains:

Active ingredient:

levocarnitine (carnifit) 300 mg;

excipients:

citric acid monohydrate 1.2 mg,

methyl parahydroxybenzoate 0.5 mg,

propyl parahydroxybenzoate 0.2 mg,

purified water up to 1 ml

Pharmacological action

Elkar is a tool for correcting metabolic processes.

L-Carnitine (a natural substance related to B vitamins) is involved in metabolic processes as a carrier of fatty acids across cell membranes from the cytoplasm to the mitochondria, where these acids are oxidized (beta-oxidation process) to form a large amount of metabolic energy (in the form of ATP). L-Carnitine increases the resistance of nervous tissue to damaging factors (hypoxia, trauma, intoxication, etc. ), inhibits the formation of keto acids and anaerobic glycolysis, reduces the degree of lactic acidosis.

The drug replenishes the alkaline reserve of blood, helps restore autoregulation of cerebral hemodynamics and increase blood supply to the affected area, accelerates reparative processes in the lesion and has an anabolic effect.

Pharmacokinetics

It is well absorbed in the intestine, the concentration in blood plasma reaches a maximum after 3 hours and remains in the therapeutic range for 9 hours. Easily penetrates the liver, myocardium, slower-in the muscles. It is excreted by the kidneys, mainly in the form of acyl esters.

Indications

The drug is used as part of complex therapy.

• intense physical activity and psycho-emotional load: to improve performance, endurance, reduction of fatigue, including the elderly;
• in the period of rehabilitation after illness and surgical interventions, injuries, including to accelerate tissue regeneration;
• complex therapy of chronic gastritis and chronic pancreatitis with a decreased secretory function;
• complex therapy of skin diseases (psoriasis, seborrheic dermatitis, localized scleroderma and lupus erythematosus diskoidna);
• hyperthyroidism mild;
• neurological manifestations in vascular, toxic and traumatic brain lesions; 
• anorexia nervosa syndrome;
• diseases accompanied by a lack of carnitine or its increased loss (myopathies, cardiomyopathies, mitochondrial diseases, hereditary diseases with concomitant mitochondrial insufficiency – – to compensate for its deficiency as part of complex therapy;
• in pediatric practice (treatment of children under 3 years of age under the supervision of a doctor): when caring for premature infants, newborns who have suffered birth trauma or asphyxia; children with a sluggish sucking reflex and low body weight gain; reduced muscle tone, with insufficient development of motor and mental functions, as well as for the prevention of these disorders in children of the “risk group”; with growth retardation and lack of body weight in children and adolescents under 16 years of age.
• in adults in sports medicine and during intensive training (during the training process when working out aerobic performance): to improve speed and strength indicators and coordination of movements, to increase muscle mass and reduce body fat, to prevent post-workout syndrome (acceleration of recovery processes after physical exertion), in case of traumatic injuries in order to accelerate muscle regeneration.

Use during pregnancy and lactation

Due to the lack of studies, use during pregnancy and lactation is not recommended.

Contraindications

Individual intolerance to the components of the drug.

Side effects

Possible allergic reactions, gastralgia, dyspepsia, myasthenia gravis (in patients with uremia).

Interaction

Glucocorticosteroids contribute to the accumulation of the drug in tissues (except for the liver), other anabolics enhance the effect.

How to take, course of use and dosage

1. The drug is used as part of complex therapy. Inside 30 minutes before meals, additionally diluting with liquid.

For prolonged physical and psychoemotional loads: from 0.75 g (1/2 measuring spoon or 2.5 ml) 3 times a day to 2.25 g (1.5 measuring spoon or 7.5 ml) 2-3 times a day.

For anorexia nervosa, as well as during rehabilitation after diseases and surgical interventions and injuries: 1.5 g (1 scoop or 5 ml) 2 times a day. The course of treatment is for 1-2 months.

In the complex therapy of chronic gastritis and chronic pancreatitis with reduced secretory function: 0.375 g (1/4 scoop or 1.25 ml) 2 times a day. The course of treatment is 1-1.5 months.

For the treatment of skin diseases: 0.75 g (1/2 scoop or 2.5 ml). The course of treatment is 2-4 weeks.

For mild hyperthyroidism: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after a 1-2-month break or prescribed for 3 months without a break.

For vascular, toxic and traumatic brain injuries: 0.75 g (1/2 scoop or 2.5 ml) per day. The course of treatment is within 3-5 days. If necessary, a second course is prescribed after 12-14 days.

For diseases that are accompanied by a lack of carnitine (primary and secondary carnitine deficiency): up to 50-100 mg / kg (2-5 drops/kg) of body weight with a multiplicity of 2-3 times a day. The course of treatment is within 3-4 months.

Children are prescribed as an additive to sweet dishes (jelly, compote, juices).

For children under 3 years of age, the dose is determined by the attending physician. From 3 to 6 years – in a single dose of 0.1 g (5 drops) 2-3 times a day, in a daily dose of 0.2-0.3 g (11-16 drops). The course of treatment is 1 month. Children from 6 to 12 years are prescribed in a single dose of 0.2-0.3 g (11-16 drops) 2-3 times a day, in a daily dose of 0.4-0.9 g (22-48 drops). The course of treatment is at least 1 month.

For stunted growth: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after a 1-2-month break or prescribed for 3 months without a break.

In sports medicine and intensive training: 2.5 g 1-3 times a day (daily dose 2.5-7.5 g); in the case of use for therapeutic purposes-70-100 mg / kg / day (5-7.5 g/day). Admission courses: 3-4 weeks in the pre-competition period. During the training process – up to 6-8 weeks.

2. One ampoule contains 0.5 g of the Active ingredient.

Elkar is administered intravenously by slow drip or jet (2-3 min) or in/m. Before intravenous use, the contents of the ampoule are dissolved in 100-200 ml of solvent (0.9% sodium chloride solution or 5% dextrose (glucose) solution).

In acute disorders of cerebral circulation,1 g/day (2 ampoules) is prescribed for 3 days, and then 0.5 g/day (1 ampoule) for 7 days. After 10-12 days, repeated courses are possible within 3-5 days.

When prescribing the drug in the subacute and recovery period, with dyscirculatory encephalopathy and various brain lesions, carnitine deficiency, patients are administered Elkar solution at the rate of 0.5-1 g / day (1-2 ampoules) intravenously (drip, jet) or in / m (2-3 times a day) without dilution for 3-7 days. If necessary, a second course is prescribed after 12-14 days.

Overdose

Symptoms: dyspeptic disorders, myasthenic disorders (in patients with uremia).

Treatment: gastric lavage, taking activated charcoal.

Special instructions

Treatment of children under 3 years of age should be carried out under the supervision of a doctor.

The drug does not affect the performance of potentially dangerous activities that require special attention and quick reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc. )

Form of production

Solution for oral use

Storage conditions

In a dark place, at a temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Levocarnitine

Dosage form

solution for oral use

Purpose

For athletes, For the elderly, For Children as prescribed by a doctor, For adults, For children from birth

Indications

Malnutrition, Gastritis, Concussion and other traumatic brain injuries, Hyperthyroidism, Eczema, Chronic Pancreatitis, Recovery Period, Intense physical activity, Psoriasis