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What is Evrenzo?

The ground-breaking drug Evrenzo (roxadustat) addresses anemia brought on by chronic kidney disease (CKD). Approved for this disorder, this is the first HIF-PH inhibitor, therefore revolutionizing the therapy of anemia in CKD sufferers.

How Evrenzo Works

Consider this: our bodies naturally react to low oxygen levels by generating more erythropoietin (EPO), a hormone that boosts red blood cell creation. By raising EPO synthesis and enhancing iron availability, Evrenzo replicates this natural reaction. This thus increases hemoglobin levels and red blood cell count, countering anemia.

Evrenzo Composition

There are three strengths to Evrenzos composition: seventy, one hundred, and fifty mg. The tablets are film-coated and include several colors and forms for simple recognition:

• Red, spherical, film-coated tablets debossed with 70 on one side, Evrenzo 70 mg
• Red, oval, film-coated tablets debossed with 100 on one side, Evrenzo 100 mg
• Red, almond-shaped, film-coated tablets with debossed 150 on one side Evrenzo 150 mg

Twelve film-coated tablets packed in PVC/aluminium perforated blisters make up each box.

Benefits of Evrenzo

For those suffering with anemia related to CKD, Evrenzo has several advantages:

• Reduced anemia symptoms follow from better red blood cell count and hemoglobin levels.
• Less reliance on intravenous iron provides a more practical and less intrusive course of treatment.
• Patients with CKD can enjoy higher general well-being and more vitality, therefore improving their quality of life.

What is Evrenzo Used For?

Evrenzo is intended especially to treat adult chronic renal disease-related anemia symptoms. Commonly occurring in CKD, anemia—characterized by low red blood cell count—can seriously affect a patients general health and well-being.

How to Use Evrenzo

Prescription-only availability of Evrenzo makes it advisable to start it under the direction of a physician familiar with treating anemia. Individual patient considerations, including weight, affect the amount and frequency of administration.

Evrenzo Dosage and Administration

Usually taken three times a week, Evrenzo is not taken consecutively on days. The patients weight determines the beginning dosage; the doctor might change it if necessary.

• Patients switching from ESAs can have Evrenzo utilized in place of them.
• Patients on ESAs now can have ESAs replaced with Evrenzo for those who are stable on their present ESA medication.

Side Effects of Evrenzo

Like every medicine, Evrenzo could have side effects. The most often occurring adverse effects consist of:

• High blood pressure—hypertension
• Thrombosis in blood vessels connected to dialysis: vascular access
• Gastritis
• Ankle and foot swelling known as peripheral edema
• Hyperkalemia (high potassium levels)
• Naesia

See your doctor right away if you develop any unexpected or recurring side symptoms.

Who Should Not Use Evrenzo?

Not everyone will find Evrenzo suitable. If you are allergic to roxadustat or any component in Evrenzo, you should not use it.

• Have extreme, uncontrollably high blood pressure.
• Get unstable angina pectoris or chest discomfort.
• Had a stroke or recent heart attack.

Before beginning Evrenzo treatment, be sure your doctor is aware of all your medical issues and medications.

Evrenzo Storage

Store Evrenzo at room temperature (below 30 °C) in the original packaging. Keep Evrenzo far from reach for young people.

Important Information About Evrenzo

Prescription drugs like Evrenzo should be taken just as advised by your doctor. Keep Evrenzo private from others.

See your doctor or chemist if you have questions or worries regarding Evrenzo.

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