Composition
Composition per tabletthe Active ingredient: Nitrofural (furacilin) – 20 mgsupport substance: sodium chloride-800 mg
Pharmacological action
Pharmacodynamics antimicrobial agent, a derivative of nitrofuran. Bacterial flavoproteins, reducing the 5-nitro group, form highly reactive amino derivatives that can cause conformational changes in proteins (including ribosomal) and other macromolecules, leading to bacterial death. Active against gram-positive and Gram-negative bacteria (including Staphylococcus spp., Streptococcus spp., Escherichia coli, Clostridium perfringens). Resistance develops slowly and does not reach a high degree. Pharmacokineticsexternal and topical application, absorption is negligible. Penetrates through histohematic barriers and is evenly distributed in fluids and tissues. The main pathway of metabolism is the reduction of the nitro group. It is excreted by the kidneys and partially with bile.
Indications
Externally: purulent wounds, bedsores, burns of II-III degrees, minor skin injuries (including abrasions, scratches, cracks, cuts). Locally: blepharitis, conjunctivitis, osteomyelitis, empyema of the paranasal sinuses and pleura; urinary tract infections-flushing, acute tonsillitis, stomatitis, gingivitis. If necessary, please consult your doctor before using the medicine.
Use during pregnancy and lactation
Before using the drug, if you are pregnant, or think that you might be pregnant, or are planning to become pregnant, while breastfeeding, you should consult your doctor. Use during pregnancy and lactation is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.
Contraindications
Hypersensitivity to nitrofural, nitrofuran derivatives and/or other components of the drug, bleeding, allergic dermatoses, severe renal dysfunction.
Side effects
Possible allergic reactions, dermatitis, itching of the skin. If any of the side effects listed in the instructions get worse, or any other side effects that are not listed in the instructions are noted, you should immediately inform your doctor.
Interaction
Not studied.
How to take, course of use and dosage
Topically, externally in the form of a 0.02% freshly prepared aqueous solution: immediately before use, one tablet (20 mg of furatsilin) is dissolved in 100 ml of distilled or warm boiled water. Hot water is recommended for faster dissolution. The solution is then cooled to room temperature. Externally: in the form of an aqueous 0.02% solution – irrigate the wounds, apply wet bandages. Topically: blepharitis, conjunctivitis-instillation of an aqueous 0.02% solution into the conjunctival sac. Osteomyelitis after surgery – washing the cavity, followed by applying a wet bandage.
Overdose
No overdose cases have been reported.
Special instructions
Influence on the ability to drive vehicles, mechanisms The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of reach of children.
Active ingredient
Nitrofural
Dosage form
soluble tablets
Description
Pregnant women as prescribed by a doctor, Children as prescribed by a doctor, For adults, Nursing mothers as prescribed by a doctor
Indications
Tonsillitis, Pressure Sores, Gum disease, Conjunctivitis, Stomatitis, Eye Infections, Blepharitis, Burns, Sore Throat, Purulent wounds, Minor skin injuries
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