Composition
Active ingredient:
100 mg nitrofurantoin
Pharmacological action
Furadonin – antibacterial.
Indications
Infectious diseases of the urinary tract: pyelitis, pyelonephritis, cystitis, urethritis.
Contraindications
Severe heart failure, liver and kidney diseases hypersensitivity to the drug.
Side effects
Possible feeling of epigastric discomfort, anorexia, nausea, vomiting, diarrhea, hepatitis, cholestatic jaundice,
cough, chest pain, shortness of breath, pulmonary infiltrates, interstitial pneumonitis or fibrosis, shortness of breath, the decline of respiratory function;
peripheral neuropathy, headache, nystagmus, dizziness, drowsiness;
leukopenia, eosinophilia, granulocytopenia, agranulocytosis, thrombocytopenia, hemolytic anemia, megaloblastic anemia (changes are reversible);
superinfection of the genitourinary tract, often caused by Pseudomonas aeruginosa;
urticaria, angioedema, pruritus, rash.
Very rarely – anaphylactic shock, asthma attack (in patients with a history of asthma), drug fever, exfoliative dermatitis, erythema multiforme, “flu-like” symptoms, arthralgia.
Interaction
The simultaneous use of nalidixic acid and antacids containing magnesium trisilicate reduces the antibacterial effect. Incompatible with fluoroquinolones.
Drugs that block tubular secretion reduce the antibacterial effect (by reducing the concentration of nitrofurantoin in the urine) and increase the toxicity (increases the concentration in the blood) of the drug.
How to take, course of use and dosage
Adults are prescribed inside 100-150 mg 3-4 times a day. The course of treatment is 5-8 days.
If there is no effect during this period, it is not advisable to continue treatment.
Maximum doses: single dose – 300 mg, daily dose-600 mg.
Children are usually prescribed Furadonin at the rate of 5-8 mg / kg per day in 3-4 doses.
Special instructions
The risk of developing peripheral neuropathy increases in patients with anemia, diabetes mellitus, electrolyte imbalance, B vitamin deficiency, and severe renal insufficiency.
The drug should not be prescribed for the treatment of diseases of the cortical substance of the kidneys, with purulent paranephritis and prostatitis.
To reduce the risk of side effects from the gastrointestinal tract, it is advisable to prescribe the drug with food or milk.
Furadonin is not prescribed in combination with drugs that cause impaired renal function.
When using Furadonin during lactation, it is necessary to decide whether to stop breastfeeding.
Form of production
Tablets
Storage conditions
Store in a dry place, protected from light.
Active ingredient
Nitrofurantoin
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
For adults by doctor’s prescription, Children by doctor’s prescription, Children over 12 years of age
Indications
Urinary Tract Infections, Urethritis
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Side effects of Furadonin, pills 100mg, 20pcs.
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