ATC code | V08C A09 |
---|---|
CAS Number | 158924-72-7 |
Other product names | Gadavist, Gadobutrol |
Dosage form | Solution for injection |
Active ingredient | Gadobutrol |
Other ingredients | Trometamol, Sodium, Calcium sodium butrol, Water for injection |
Pharmacological classification | Paramagnetic contrast agent |
Pharmacological action | Contrast enhancement in magnetic resonance imaging (MRI) |
Storage conditions | Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) |
Gadovist Solution: What It Is and How It’s Used
Which is Gadovist solution? One mmol/mL syringe, 7.5 ml, five pieces?
What is Gadovist Solution?
In magnetic resonance imaging (MRI) scans, 1 mmol/mL 7.5 ml syringes (5 pcs) are a contrast agent. This gadolinium-based contrast agent (GBCA) enables clinicians to more clearly view several bodily areas during an MRI scan. Presipped in single-dose vials and pre-filled disposable syringes, gadovist is a sterile, clear, colorless to pale yellow solution for injection containing 604.72 mg gadobutrol per mL (equivalent of 1 mmol gadobutrol/mL).
Gadovist Solution Structure
Gadovist solution 1 mmol/mL 7.5 ml syringes, five pieces count
What is Gadovist Solution Made Of?
The active component in 1 mmol/mL 7.5 ml syringes (5 pieces) is gadobutrol. Each mL of Gadovist solution (1 mmol/mL) in 7.5 mL syringes (5 pieces) has 604.72 mg of gadobutrol (equivalent of 1.0 mmol gadobutrol with 157.25 mg gadolinium). Along with other components, including sodium, calcium, sodium butrol in water for injection, and trometamol, using hydrochloric acid or sodium hydroxide, the pH of Gadovist solution (1 mmol/mL, 7.5 ml syringes, 5 pieces) is changed to lie between 6.6 and 8.0.
Benefits and Effects of Gadovist Solution
A paramagnetic contrast agent, gadovist solution 1 mmol/mL, 7.5 ml syringes (5 pieces), improves tissue and organ signal during an MRI scan. This clarifies some sections of the body for doctors, which is beneficial in the diagnosis and treatment process for many different diseases.
- Gadovists address Detect and visualize in adult and pediatric patients, including term neonate regions with broken blood-brain barrier and/or aberrant vascularity of the central nervous system, using 1 mmol/mL 7.5 mL syringes (5 pieces).
- Evaluate the degree of infections, cancers, and other diseases.
- Direction surgical operations.
- Track the success of the treatment.
What is Gadovist Solution Used For?
Gadovist solution is made with 1 mmol/mL 7.5 ml syringes in a five-piece count. Various MRI scans employ 1 mmol/mL 7.5 ml syringes (5 pieces).
- Brain MRI is one of them.
- MRI for Spine Development
- Abdominal MRI
- Pelvic MRI
- MRI for Muscles and Skeletal Conditions
- MRI for Cardiac Devices
- MRI in Vascular Systems
How is Gadovist Solution Administered?
One mmol/mL syringe with 7.5 ml capacity Five pieces per set.
Gadovist Solution Administration
Intravenous administration of 1 mmol/mL in 7.5-ml syringes (5 pieces) is handled by a medical practitioner. The type of MRI scan being done as well as the patients weight will affect the dosage of Gadovist solution (1 mmol/mL) in 7.5 ml syringes (5 pieces). For both adult and pediatric patients—including term neonates—the advised dosage of gadovist is 0.1 mL/kg body weight (0.1 mmol/kg).
Gadovist Solution: Dosage and Administration
The advised dose of Gadovist solution (1 mmol/mL, 7.5 ml syringes, 5 pieces) is 0.1 mL/kg body weight (0.1 mmol/kg). The body weight of the patient will help one decide the dosage to be given. A patient weighing seventy kg, for instance, would get seven milliliters of gadovist solution in 1 mmol/mL syringes in a five-piece set. Compared to certain other gadolinium-based contrast agents, gadovist is prepared at a higher concentration—1 mmol/mL—which reduces volume of administration.
Side Effects of Gadovist Solution
Though not everyone experiences side effects, a Gadovist solution 1 mmol/mL, 7.5 ml syringes, 5 pieces might produce side effects, like any drug. Headache, nausea, and vomiting rank among the most often occurring adverse effects. Usually moderate, these side effects clear on their own. See a doctor right away if you have any major adverse effects, including trouble breathing, chest pain, or swelling of the tongue, lips, or cheeks.
Contraindications of Gadovist Solution
Patients having a history of severe hypersensitivity responses to gadobutrol or any other component of Gadovist solution 1 mmol/mL 7.5 ml syringes (5 pieces) should not use this solution. Patients with end-stage renal illness or severe renal impairment also have contraindications.
Gadovist Solution Storage
Gadovist fixes Though they could be kept refrigerated (2–8°C or 36–46°F), 1 mmol/mL 7.5ml syringes (5 pieces) should be stored at room temperature (25°C or 77°F). Out of reach of children, keep Gadovist solution 1 mmol/mL in 7.5-ml syringes (5 pieces) dry from light and moisture.
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