ATC code | A10BB03 |
---|---|
CAS Number | 10238-25-5 (Glibenclamide) & 657-24-9 (Metformin) |
Other product names | Glucovance, Daonil Metformin, Sambeta-M, GFORMIN, Glimet, Glucored, Duotrol SR, Glifil M Forte, Glibenmet, GLITRAC-M, Genericart GlibenclamideMetformin, Glibenclamide/metformin, GLIBEMIDE FORTE |
Dosage form | Film-coated tablets |
Active ingredient | Glibenclamide and Metformin hydrochloride |
Other ingredients | May vary depending on the manufacturer, but commonly include: lactose monohydrate, maize starch, povidone, crospovidone, magnesium stearate, hypromellose, titanium dioxide, macrogol 400, iron oxide yellow, iron oxide red, and talc. |
Pharmacological classification | Antidiabetic agents |
Pharmacological action | Stimulates insulin release from the pancreas, lowers glucose production in the liver, delays glucose absorption from the intestines, increases the body’s sensitivity to insulin |
Storage conditions | Store in a cool, dry place, protected from light. Keep out of reach of children. |
Glibenclamide plus Metformin: A Comprehensive Guide
Glibenclamide plus metformin is what? You might be asking. Treating type 2 diabetes with Glibenclamide+Metformin is a combo medicine. It blends metformin, a biguanide, with glibenclamide, a sulfonylurea, two separate forms of diabetes drugs. This unusual mix acts in concert to help regulate your blood sugar levels.
Glibenclamide+Metformin Composition
Five milligrams of glibenclamide and 500 mg of metformin are found in Glibenclamide+Metformin tablets. This particular mix offers a complete answer for better blood sugar control and lets one approach type 2 diabetes management.
Benefits and Effects of Glibenclamide+Metformin
For those with type 2 diabetes, glibenclamide+metformin has several advantages.
- Enhanced management of blood sugar: Working together, glibenclamide and metformin drastically reduce blood sugar levels, hence improving management of your diabetes.
- Maintaining steady blood sugar levels can drastically lower the risk of long-term diabetic consequences like kidney disease, heart disease, stroke, and nerve damage.
- Metformin helps your body become more sensitive to insulin, enabling more effective usage of glucose by your cells.
- Further contributing to improved blood sugar control is metformins ability to help your liver create less glucose.
Uses of Glibenclamide+Metformin
Type 2 diabetes is the main condition treated with glibenclamide and metformin. Usually, it is advised when diet and exercise by themselves are insufficient to control blood sugar levels.
How to Use Glibenclamide+Metformin
When using Glibenclamide+Metformin, its imperative to closely follow your doctors directions. Your specific requirement and medical background will determine the amount and frequency.
Usually, you take one tablet once or twice a day—typically alongside meals. This reduces the possibility of stomach disturbance.
Dosages and Administration of Glibenclamide+Metformin
Usually one pill (5 mg glibenclamide + 500 mg metformin) given once or twice daily is the advised starting dose. Your doctor might change the dosage depending on your blood sugar level and reaction to treatment.
One should take Glibenclamide+Metformin exactly as advised. Never modify the dosage without seeing your doctor or skip doses.
Side Effects of Glibenclamide+Metformin
Glibenclamide+Metformin has side effects, like any drug; however, not everyone suffers from them. Some typical side effects are:
- Problems with the gastrointestinal system: Commonly occurring especially during the start of treatment include nausea, vomiting, diarrhea, and stomach distress. Usually, these adverse effects pass as your body adjusts to the drug.
- Low blood sugar—hypoglycemia—is a possible adverse effect of glibenclamide. Among the symptoms might include confusion, weakness, dizziness, and perspiration. Knowing how to identify and treat hypoglycemia is vital.
- Metformin can affect the absorption of vitamin B12; hence, regular monitoring could be required.
See your doctor right away if you develop any severe or recurring adverse effects.
Contraindications for Glibenclamide+Metformin
Not everyone will find Glibenclamide+Metformin appropriate. Those having it should not utilize it personally.
- Medication for type 1 diabetes is useless in curing this condition.
- Diabetic ketoacidosis is a dangerous disorder whereby a lack of insulin causes your body to generate ketones.
- Glibenclamide+Metformin can be dangerous for those with compromised liver or renal ability.
- Severe heart failure: In some circumstances, metformin aggravates heart failure.
- Abuse of alcohol raises the rare but severe side effect of metformins lactic acidosis risk.
- Glibenclamide allergy or metformin allergy: You should not use this medicine if you know you have an allergy to either ingredient.
Storage Conditions for Glibenclamide+Metformin
Correct storage of Glibenclamide+Metformin guarantees the efficacy and safety of your medication.
- Store it somewhere cool, dry. Steer clear of storing it in direct sunlight or extremes of temperature.
- Always make sure your medication is out of reach for dogs and youngsters.
- Throw away expired medications; avoid using Glibenclamide+Metformin past the date indicated on the label.
Important Considerations
Before beginning Glibenclamide+Metformin, be sure your doctor knows your medical history. This covers any past illnesses, allergies, or drugs you now take.
While using Glibenclamide+Metformin, regular blood sugar monitoring is crucial to guarantee efficient control and, should necessary, dosage adjustment.
For specific advice and direction on the usage of Glibenclamide+Metformin, always speak with your doctor or chemist.
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