ATC code | A10BD01 |
---|---|
CAS Number | 5687-28-4 (Glibenclamide), 657-24-9 (Metformin) |
Other product names | Glucotaj-ZET, GLIBIMIDE M, Glifil M, Glucored, Genericart GlibenclamideMetformin, GLIBENCLAMIDEMETFORMIN, Glimet, Glibomet, Metglib, Gluconorm, GLIBOMET 400 MG 2.5 MG FILM-COATED TABLETS |
Dosage form | Tablets |
Active ingredient | Glibenclamide and Metformin Hydrochloride |
Other ingredients | May vary depending on the manufacturer and specific formulation. Common excipients include: Microcrystalline cellulose, crospovidone, magnesium stearate, hypromellose, titanium dioxide, macrogol, and iron oxide |
Pharmacological classification | Antidiabetic agents, combinations |
Pharmacological action | Stimulates insulin release from pancreatic β-cells, reduces glucose output from the liver, increases insulin sensitivity, improves glucose tolerance by lowering both basal and postprandial plasma glucose |
Storage conditions | Store below 30°C in a dry place. Protect from light and moisture. |
Glibenclamide+Metformin 2.5 mg+400 mg: What Is It?
Adults with type 2 diabetes use the combo drug Glibenclamide+Metformin 2.5 mg+400 mg to lower their blood sugar levels. Combining metformin, a biguanide, with glibenclamide, a sulfonylurea, it offers two potent antidiabetic medicines.
Glibenclamide + Metformin 2.5 mg + 400 mg Composition
Every pill carries 400 mg of metformin hydrochloride and 2.5 mg of glibenclamide. In those with type 2 diabetes, this mix acts in concert to properly control blood sugar levels.
Benefits and Effects of Glibenclamide+Metformin 2.5 mg+400 mg
For those with type 2 diabetes, glibenclamide+metformin 2.5 mg+400 mg provides a number of advantages.
- This combo drug helps control blood sugar levels, lowering the risk of complications related to uncontrolled diabetes.
- Glibenclamide stimulates the pancreas to produce more insulin, a hormone that facilitates the absorption of glucose from the bloodstream by means of which cells grow.
- Metformin lowers hepatic glucose generation, so helping to regulate blood sugar levels.
- For those with type 2 diabetes, metformin can assist with weight control, therefore benefiting them.
Glibenclamide+Metformin 2.5 mg+400 mg is used for the treatment of type 2 diabetes in adults when diet and exercise alone are not sufficient to manage blood sugar levels.
How to Use Glibenclamide+Metformin 2.5 mg+400 mg
Regarding dose and administration, always strictly follow the advice of your doctor. Usually, one tablet taken once daily with a meal forms the initial dosage. Your doctor could change the dosage depending on your particular requirements and reaction to the treatment.
Dosage and Administration of Glibenclamide+Metformin 2.5mg+400mg
Glibenclamide+Metformin 2.5mg+400mg dose differs depending on personal need. For customized dosage advice, see your doctor.
Side Effects of Glibenclamide+Metformin 2.5mg+400mg
Glibenclamide+Metformin 2.5mg+400mg has side effects, just as any medicine. Typical side effects are:
- Not feeling well
- Stools
- Stomach disturbance
- Low blood sugar, sometimes known as hypoglycemia:
- headache
See your doctor right away if you have any major or recurring adverse effects.
Contraindications for Glibenclamide plus metformin 2.5 mg+400 mg
Not fit for everyone is Glibenclamide+Metformin 2.5 mg+400 mg. It is contraindicated in those having:
- Type 1 diabetic
- Diabetic ketosacidosis
- Major liver or kidney disease
- Great heart failure
- An allergy to metformin or glibenclamide
Important Considerations
Tell your doctor about any pre-existing medical issues, allergies, and drugs you now take before beginning Glibenclamide+Metformin 2.5 mg+400 mg. Safe and efficient use of this drug depends on this knowledge.
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