Composition
Active ingredient:
S-adenosylmethionine 400 mg;
Auxiliary substances:
polyplasdon X El-10 (crospovidone);
MCC;
mannitol;
magnesium stearate;
Shell:
acrylics;
oxypropylmethylcellulose;
plasdon ES-630;
polyethylene glycol 6000.
Pharmacological action
Heptor – hepatoprotective, antidepressant.
Pharmacodynamics
Heptor belongs to the group of hepatoprotectors, has antidepressant activity, detoxifying, regenerating, antioxidant, antifibrosing and neuroprotective effects.
Ademetionine is involved in the body’s biochemical processes, while stimulating the production of endogenous ademetionine.
Ademetionine (S-adenosyl-L-methionine) — a biological substance found in all tissues and fluids of the body.
Its molecule is included in most biological reactions both as a donator of the methyl group-methylation of phospholipids in the lipid layer of the cell membrane (transmethylation), and as a precursor of physiological thiol compounds — cysteine, taurine, glutathione, one of the most important intracellular antitoxic agents, CoA, etc. (transsulfation), and as a precursor of polyamines-putrescine, which stimulates cell regeneration and proliferation of hepatocytes, spermidine, spermine, which are part of the ribosome structure (aminopropylation).
Indications
- intrahepatic cholestasis;
- hepatitis of various origins: toxic (including alcoholic), viral, medicinal (antibiotics, antitumor, antituberculous and antiviral drugs, tricyclic antidepressants, oral contraceptives);
- precirrotic conditions;
- cirrhosis of the liver;
- encephalopathies of secondary genesis;
- depressive syndromes, including secondary ones;
- alcohol withdrawal syndrome.
Use during pregnancy and lactation
It is not recommended to prescribe Heptor in the first and second trimesters of pregnancy and during lactation (breastfeeding).
Contraindications
Hypersensitivity
Side effects
From the digestive tract: Â when taken orally-heartburn, pain or discomfort in the epigastric region, dyspeptic phenomena.
Other services: Â allergic reactions.
How to take, course of use and dosage
Inside, swallowing whole, without chewing.
To improve the therapeutic effect, tablets are recommended to be taken between meals.
During maintenance therapy, the recommended daily dose is 800-1600 mg (2-4 tablets).
The duration of maintenance therapy is 2-4 weeks on average.
Special instructions
Given the tonic effect of Heptor, the drug is not recommended for use before bedtime.
Use in patients with liver function disorders
When prescribing Heptor to patients with cirrhosis of the liver on the background of hyperazotemia, systematic monitoring of blood nitrogen levels is necessary.
Composition
Tablet Form of production
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25 °C.
Shelf life
2 years
Active ingredient
Ademetionine
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
For adults as prescribed by a doctor, Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor
Indications
Alcoholism, Hepatitis, Depression, Cholecystitis, Liver Damage, Cirrhosis
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Side effects of Heptor pills 400mg, 20pcs.
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