ATC code | L01XX03 |
---|---|
CAS Number | 134949-65-3 |
Other product names | Camptosar, Irinotecan medac, Irinotecan Mylan, Irinotecan Hydrochloride, Irinotecan Teva |
Dosage form | Concentrate for solution for infusion |
Active ingredient | Irinotecan hydrochloride trihydrate |
Other ingredients | Sorbitol, lactic acid, water for injections, sodium hydroxide |
Pharmacological classification | Cytostatic (anti-cancer medicine), Topoisomerase I inhibitor |
Pharmacological action | Inhibits topoisomerase I, prevents DNA replication, induces apoptosis |
Storage conditions | Store in a refrigerator (2°C – 8°C) |
Irinotecan-Teva concentrate 20 mg/mL, 5 ml, 1 pc
Comprising the active ingredient irinotecan hydrochloride, Irinotecan-Teva concentrate (20 mg/mL, 5 mL, 1 pc) is an anticancer agent. Adults with advanced colon and rectal cancer, either alone or in conjunction with other medications, are treated with it.
Product Composition
Twenty mg/mL irinotecan hydrochloride (equal to 17.33 mg/mL irinotecan) makes up Irinotecan-Teva concentrate 20 mg/mL, 5 mL, 1 pc. For injections, it also includes lactic acid, sorbitol, and water. Sodium hydroxide helps one to change the pH of the solution to 3.5.
Advantages and Influences of the Product
Working by blocking topoisomerase I, an enzyme, irinotecan-Teva Concentrate helps The replication of DNA, the genetic material of cells, depends on this enzyme in great part. Irinotecan stops topoisomerase I, therefore stopping the multiplication of cancer cells.
Purpose of Use
Advanced colorectal cancer—that is, colon and rectal cancer—is treated with irinotecan-Teva Concentrate. It is sometimes used in concert with other chemotherapeutic agents.
A healthcare provider will administer Irinotecan-Teva concentrate intravenously—that is, into a vein. Your particular requirements and the type of cancer you have will determine the amount and frequency of administration.
Dosage and Administration
Your doctor will decide upon the Irinotecan-Teva concentrate dosage. Usually, it is injected intravenously for ninety minutes. Every three weeks, the advised single-agent dosage is 350 mg/m2. Still, the dosage could be changed according to your particular demand.
Side Effects
Though not everyone suffers negative effects, Irinotecan-Teva concentrate can have them like any drug. Some typical side effects consist in:
- Diarrhea
- vomiting and nausea
- Exhaustion
- Loss of appetite
- Baldness
- Mouth ulcers
- Low blood cell counts—anemia, thrombocytopenia, neutropenia
Major side effects are conceivable. If you have any strong or recurring adverse effects, you should discuss them with your doctor.
Contraindications
Patients known to be hypersensitive to the medicine or its excipients should not use irinotecan-Teva Concentrate.
Storage
Store Irinotecan-Teva concentrate away from direct sunlight at room temperature.
Important Information
Irinotecan-Teva concentrate is a strong medication with major adverse effects; hence, one should keep this in mind. Before beginning therapy with this medication, you should be sure your doctor knows your medical history.
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Irinotecan-Teva concentrate is an important medication for treating advanced colorectal cancer. Its use should be undertaken only under the supervision of a qualified healthcare professional. Its crucial to be aware of the potential side effects and contraindications, as well as to follow proper dosage and administration instructions. For more information about Irinotecan-Teva concentrate and its use, consult with your doctor or pharmacist.
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Side effects of Irinotecan-Teva concentrate 20mg/ml 5ml, 1pc
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