ATC code | L04AA14 |
---|---|
CAS Number | 882781-08-7 |
Other product names | Xeljanz, Xeljanz XR, Tofacitinib, Tofacent |
Dosage form | Tablet, film-coated; Tablet, film-coated, extended release; Oral solution |
Active ingredient | Tofacitinib |
Other ingredients | Microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, triacetin, iron oxide red, iron oxide yellow |
Pharmacological classification | Janus kinase (JAK) inhibitor |
Pharmacological action | Immunosuppressant, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular course juvenile idiopathic arthritis, ulcerative colitis |
Storage conditions | Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) |
What is Jaquinus?
Jaquinus is a prescription drug used to treat a variety of inflammatory diseases, including:
- Rheumatoid arthritis
- Psoriatic arthritis
- Ulcerative colitis
- Juvenile idiopathic arthritis
This tablet contains tofacitinib, a medication designed to prevent the function of several enzymes known as Janus Kinases (JAKs). Jaquinus helps lower inflammation and discomfort by blocking these enzymes, which are part of the inflammatory reaction the body mounts.
Composition of Jaquinus
Each Jaquinus tablet contains five mg of tofacitinib citrate—equivalent to five milligrams of tofacitinib. This white film-coated tablet is round in form and boasts Pfizer on one side and JKI 5 on the other.
Advantages and Results of Jaquinus
Targeting the underlying source of inflammation, Jaquinus helps to ease the symptoms of many inflammatory disorders. Many advantages can follow from this, including:
- Less edema and joint pain
- Enhanced movement and physical ability
- Less stomach irritation
- Enhanced living standards
What is Jaquinus Used For?
Jaquinus is applied in treatment of:
- Rheumatoid arthritis (RA), a chronic autoimmune condition that inflames the joints.
- Psoriatic arthritis (PsA), a type of arthritis experienced by those having psoriasis.
- Ulcerative colitis (UC), an inflammatory bowel illness affecting the colon.
- Juvenile idiopathic arthritis (JIA), a kind of arthritis that strikes minors.
How to Use Jaquinus
Jaquinus is taken orally, either with or without food. The ailment being treated and the particular patients requirements will affect the advised dosage. Your doctor will decide on your appropriate dosage and frequency of use. Its imperative to take Jaquinus exactly as directed and closely follow the advice of your physician. Neither change the dosage nor stop taking it without first seeing your doctor.
Dosage and Administration of Jaquinus
The ailment being treated will affect the dosage of Jaquinus as well as the particular patients demand. Its imperative to take Jaquinus exactly as directed and closely follow the advice of your physician. Following are some broad dose recommendations:
- Rheumatoid arthritis: The advised beginning dosage is 5 mg twice daily. Your response to treatment may cause your doctor to change the dosage.
- Psoriatic arthritis: Starting dosage is either 5 mg twice daily or 11 mg once daily (Jaquinus XR). Your response to treatment may cause your doctor to change the dosage.
- Ulcerative Colitis: For at least 8 weeks, the advised starting dosage is 10 mg twice daily; subsequently, either 5 or 10 mg twice daily. Your response to treatment may cause your doctor to change the dosage.
- Juvenile Idiopathic Arthritis: The childs weight and age will affect the advised dose. Your childs suitable dosage will be decided upon by your doctor.
Side Effects of Jaquinus
Though not everyone experiences them, like all drugs, Jaquinus can have negative effects. Some typical side effects consist in:
- Pain in the head
- Appause
- The diarrhea
- Infections of the upper respiratory tract
- Rising cholesterol levels
More severe adverse effects could arise and include:
- Higher chance of infection
- Blood aggregates
- Liver issues
- Issues with the heart
Tell your doctor about any side effects you find occurring. They can guide you in controlling these side effects and ascertain whether Jaquinus is the correct medicine for you.
Contraindications of Jaquinus
Not everyone would find Jaquinus appropriate. You shouldnt take Jaquinus if you:
- Are allergic to tofacitinib or another Jaquinus component.
- Have a major infection.
- Exude serious liver disease.
- Are either nursing or pregnant.
See your doctor if you have any queries or worries regarding whether Jaquinus is suitable for you. They can guarantee Jaquinus is safe and efficient for your particular circumstances and offer you tailored guidance.
Important Information About Jaquinus
Jaquinus raises your chances of certain infection development. Tell your doctor about any symptoms like fever, chills, sore throat, or coughing; these indicate an infection. While you take Jaquinus, your doctor could have to keep an eye on you for infections.
Jaquinus also raises the chance of blood clots. Tell your doctor whether you have a family history of blood clots or if you have any risk factors for blood clots—such as obesity, smoking, or diabetes. While using Jaquinus, your doctor might have to check you for blood clots.
See your pharmacist or doctor if you have questions or concerns about Jaquinus. They can supply you further details regarding the hazards and advantages of this drug.
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