Composition
Active ingredients:
nifuratel 500 mg;
nystatin 200,000 IU;
Auxiliary substances:
dimethylpolysiloxane AK 1000 (dimethicone);
Capsule composition:
gelatin;
glycerin(glycerol);
ethylparahydroxybenzoate of sodium;
propylparahydroxybenzoate of sodium;
titanium dioxide;
iron oxide yellow;
Pharmacological action
Macmiror Complex 500 is an antimicrobial drug for topical use. It has antiprotozoal, antifungal and antibacterial effects.
Nifuratel, a derivative of nitrofuran. Highly active against a number of bacteria, fungi and protozoa (including Trichomonas vaginalis).
Nystatin is an antifungal antibiotic of the polyene group. Binding to sterols in the fungal cell membrane disrupts its permeability, which leads to cell death. Highly active against fungi of the genus Candida albicans.
The combination of nifuratel and nystatin allows you to achieve a more pronounced antifungal effect and significantly expand the spectrum of antimicrobial action.
The high efficiency and low toxicity of the drug components determine a wide range of its clinical use in the treatment of vaginitis of mixed etiology, in particular, its use for the prevention of mycoses caused by specific treatment of trichomoniasis.
Macmiror complex does not disrupt the physiological flora, which allows you to avoid the development of dysbiosis and quickly restore the normocenosis of the vagina.
Indications
Complex therapy of vulvovaginal infections caused by drug-sensitive pathogens: bacteria, Trichomonas, Candida fungi and chlamydia.
Contraindications
Hypersensitivity to one of the active ingredients or any auxiliary ingredient of the drug.
Side effects
In rare cases, allergic reactions in the form of skin rash or itching are possible.
How to take, course of use and dosage
Intravaginally, before going to bed — for 8 days,1 suppository or 2.5 g of cream 1-2 times a day (using an applicator). If necessary, the treatment is repeated after menstruation.
To achieve maximum therapeutic effect, a suppository should be inserted into the upper part of the vagina.
Suppositories are not used for treatment in childhood, it is recommended to use a vaginal cream complete with an applicator (graduated syringe).
Special instructions
It is necessary to carry out simultaneous treatment of the sexual partner because of the risk of re-infection. During treatment with the drug, sexual contact should be avoided.
How to use the graduated applicator: screw the graduated applicator onto the cream tube. Dial the required amount of cream (in accordance with the scale lines indicating the amount in grams), pressing on the tube. Disconnect from the tube, insert into the vagina, squeeze out the contents, pressing on the rod.
The presence of a special nozzle allows you to enter the cream without damaging the hymen. To do this, remove the cannula from the top of the rod and screw it onto the head of the syringe on the opposite side before inserting the cream into the vagina.
Product form
vaginal suppositories
Storage conditions
In a dry place, at a temperature not exceeding 25 °C
Shelf life
3 years
Active ingredient
Nystatin, Nifuratel
Conditions of release from pharmacies
By prescription
Dosage form
vaginal capsules
Description
Nursing mothers as prescribed by a doctor, Adults as prescribed by a doctor, Pregnant Women as prescribed by a doctor
Indications
Inflammation of the female genital organs, Vaginitis
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Side effects of Macmiror complex vaginal capsules 200000IU + 500mg, 8pcs.
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