Composition
Active ingredient: Â
Amorolfine hydrochloride 55.7 mg (equivalent to 50 mg of Amorolfine)
Auxiliary substances:
triacetin (glycerol triacetate)Â – 10.5 mg;
methyl methacrylate,
trimethylammonioethylmethacrylate chloride and ethyl acrylate copolymer (2: 0.2: 1) (ammonium methacrylate copolymer (Type A) (Eudragit RL 100)Â – 125 mg;
ethyl acetate-150 mg;
butyl acetate-50 mg;
anhydrous ethanol-up to 1 ml
Pharmacological action
Antifungal drug for external use.
It has a fungistatic and fungicidal effect due to damage to the cytoplasmic membrane of the fungus by disrupting the biosynthesis of sterols.
Reduces the content of ergosterol, accumulates the content of atypical steric non-planar sterols.
It has a wide spectrum of action. Highly active against both the common and rare pathogens of fungal nail infections: dermatophytes — Trichophyton spp. Microsporum spp. Epidermophyton spp. ; yeast — Candida spp. Cryptococcus spp. Malassezia spp. (Pityrosporum spp. ); fungi — Alternaria spp., Scopulariopsis spp. Hendersonula spp. ; mushrooms of the family Dematiaceae — Cladosporium spp., Fonsecaea spp. Wangiella spp. ; dimorphic fungi Coccidioides spp. Histoplasma spp., Sporothrix spp.
Indications
Onychomycosis caused by dermatophytes, yeast and mold fungi (if no more than 2/3 of the nail plate is affected).
Prevention of fungal nail lesions.
Contraindications
Hypersensitivity to the components of the drug.
How to take, course of use and dosage
Nail polish is applied to the affected nails 1-2 times a week.
Before use, remove the affected areas of the nail with the attached nail file, clean the surface with the attached swab moistened with alcohol; before the next application, the procedure is repeated, after removing the remaining varnish with a swab with alcohol.
Treatment is continued continuously until the new nail grows and the affected areas disappear. The duration of therapy depends on the localization and severity of the process and averages 6 months (fingernails of the fingers of the hand) or 9-12 months (fingernails of the toes).
Form of production
Nail polish.
Active ingredient
Amorolfine
Description
For adults
Indications
Fungus, Nail Fungus
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Side effects of Oflomil nail polish, 5%, 2.5ml
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