ATC code | J06BA02 |
---|---|
Other product names | Human immunoglobulin-G, IgM-enriched immunoglobulin |
Dosage form | Solution for infusion |
Active ingredient | Human plasma protein 50 mg, of which immunoglobulin at least 95 IgM 6 mg, IgA 6 mg, IgG 38 mg |
Other ingredients | Glucose monohydrate (27.5 mg/ml), sodium chloride (78µmol/ml), water for injections (ad 1 ml) |
Pharmacological classification | Immunoglobulins, normal human, for intravascular administration |
Pharmacological action | Treatment of bacterial infections (concomitantly with antibiotics), especially in immunocompromised patients and those with a suppressed immune system, prevention of Rh immunization in any Rh-negative person after incompatible transfusion of Rh-positive blood or blood products, idiopathic thrombocytopenic purpura |
Storage conditions | Store in a cool and dry place |
Pentaglobin: What is it?
Pentaglobin is a medicine containing a high concentration of immunoglobulin M (IgM), an antibody crucial for the bodys immune response. It is used to treat severe bacterial infections, particularly sepsis, when antibiotics alone are insufficient. Pentaglobin enhances the immune systems ability to fight infections, thereby strengthening it.
Pentaglobin’s Composition
Pentaglobin is a sterile solution made from pure human plasma proteins, including immunoglobulins, primarily IgG, IgM, and IgA. Each milliliter of solution contains 50 mg of plasma protein, with at least 95% being immunoglobulins. This breaks down to approximately 6 mg IgM, 6 mg IgA, and 38 mg IgG.
Pentaglobin is not a substitute for immunizations. Consult a doctor for proper vaccination regimens.
Advantages and Impact of Pentaglobin
The primary advantage of Pentaglobin is its ability to bolster the bodys resistance against severe bacterial infections. Its high IgM concentration explains its effectiveness in treating sepsis, a life-threatening condition characterized by widespread inflammation.
Pentaglobin’s Application
- Adjuvant treatment for severe bacterial infections: Pentaglobin is used alongside other medications to treat severe bacterial infections, especially sepsis, particularly in high-risk individuals who may have underlying IgA deficiency.
- Immunoglobulin substitution in immunocompromised patients: Pentaglobin replaces absent or inadequate immunoglobulins in individuals with compromised immune systems.
- Viral infections: While occasionally used in specific cases of severe viral infections, Pentaglobin is generally not recommended for viral infections.
Pentaglobin: How to Use
Pentaglobin is administered intravenously (through a vein) as an infusion. The dosage and duration of treatment depend on the patients condition and the severity of the infection. A medical professional will administer the infusion, so it is essential to follow their instructions carefully.
Pentaglobin Dose and Administration
Pentaglobin dosage varies based on patient weight and the specific ailment being treated. The standard recommended dosage is 3-5 mL/kg body weight, administered intravenously as a continuous flow. The infusion rate can be adjusted based on the patients age and tolerance. While the usual infusion rate for children and adults is 0.4 mL/kg body weight per hour, for infants and newborns, it is typically 1.7 mL/kg body weight per hour.
Side Effects of Pentaglobin
Like other medications, Pentaglobin can have side effects. Common side effects include:
- Tension
- Temperature: Chills
- Muscle aches
- Malaise (feeling unwell)
- Rash
- Vomiting
Rarely, Pentaglobin may cause more serious adverse effects, including:
- Anaphylactic response (severe allergic reaction)
- Kidney problems
- Blood clots
If you experience any adverse effects, especially severe ones, consult your doctor immediately.
Pentaglobin’s Contraindications
Pentaglobin should not be used in the following circumstances:
- Hypersensitivity to any ingredient: Do not use Pentaglobin if you are allergic to any of its components.
- Homologous immunoglobulins: hypersensitivity: Individuals with IgA deficiency may have antibodies against IgA, which could make them sensitive to Pentaglobin.
Before starting Pentaglobin treatment, inform your doctor about any allergies or medical conditions.
Pregnancy and Nursing
Controlled clinical studies have not conclusively established the safety of Pentaglobin for pregnant women. Pregnant women and nursing mothers should exercise caution when using it. Consult your doctor about the risks and benefits of using Pentaglobin during pregnancy or breastfeeding.
Crucial Information
- Pentaglobin can reduce the effectiveness of certain vaccines, including those for measles, mumps, rubella, and chickenpox. Inform your doctor about Pentaglobin use before receiving any vaccinations.
- Patients should be adequately hydrated before starting Pentaglobin treatment.
- Always consult your doctor or pharmacist for personalized guidance and to ensure the safe and effective use of Pentaglobin.
Order Pentaglobin via Medixlife Today
Pentaglobin is available now at Medixlife, your go-to source for treating severe bacterial infections. Our fast and reliable delivery ensures you have the medication you need when you need it. Order Pentaglobin online and experience the convenience and peace of mind Medixlife offers.
Best price for Pentaglobin solution 50mg/ml 50ml, 1pc in our online pharmacy!
Side effects of Pentaglobin solution 50mg/ml 50ml, 1pc
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