ATC code | R06AE01 |
---|---|
CAS Number | 1132-43-1 |
Other product names | Piperazine Citrate, Piperazine Hexahydrate |
Dosage form | Tablets, Syrup, Oral Solution, Oral Suspension |
Active ingredient | Piperazine |
Other ingredients | May vary depending on the specific formulation. Common excipients include: Citric acid, Sodium citrate, Sugar, Flavoring agents, Preservatives |
Pharmacological classification | Anthelmintic |
Pharmacological action | Paralyzes worms, causing them to be passed in the stool |
Storage conditions | Store at room temperature, away from moisture and light. |
Piperazine—what is it?
Piperazine is a medicine falling under the class of anthelmintics. Anthelmintics paralyze and remove intestinal worms from the body. Treating roundworm (ascariasis) and pinworm (enterobiasis) infestations especially calls for piperazine. Particularly in youngsters, this is a common and efficient course of treatment for many parasite diseases.
Piperazine’s Chemical Makeup
Usually featuring 500 mg of piperazine as the active component, piperazine tablets are meant for oral use. Usually taken with water, the medications are meant for oral use. The persons age, weight, and degree of the infection will all affect the precise dosage and treatment length. You really should pay close attention to what your doctor orders.
Advantages and Consequences of Piperazine
Piperazine paralyzes the worms muscles such that they cannot attach to the intestinal walls. The worms paralysis lets them be readily removed from the body via the feces. Usually, this procedure starts a few days after therapy began. Usually well accepted, piperazine causes most patients to have a notable decrease in symptoms, including itching, nausea, and stomach discomfort, within a short period of time.
Piperazine: For What Purpose?
Infections with roundworms and pinworms are the main conditions Piperazine treats. Long, thin parasites, roundworms can dwell in animal and human intestines. They can bring about weight loss, nausea, and stomach aches. Smaller parasites called pinworms inhabit the rectum and can produce great itching around the anus. Piperazine helps to eradicate these parasites and reduces the related symptoms.
How to Apply
Usually taken orally along with water, piperazine pills are: the type of infection being treated as well as the person will affect the particular dosage and frequency. You must do as your doctor or pharmacist advises. Even if you start feeling better, you should follow the advised full course of treatment. This guarantees the elimination of every parasite and stops the recurrence of the infection.
Administration and Dosage
Your doctor will decide on the piperazine pill dosage depending on your particular need. Common dose recommendations, however, include:
- Children and teenagers: Two days in a succession, three and a half grams of piperazine hexahydrate daily. Treatment might have to be repeated in one week.
- Youngsters: Dosage is calculated from body weight and needs to be decided upon by a physician. Usually, a dose is 75 mg of piperazine hexahydrate per kilogram (34 mg per pound) of body weight per day for two days in a succession.
Though occasional adverse effects may arise, piperazine is usually well tolerated. Usually modest and transient, these adverse effects Typical side consequences consist of:
- Not feeling good
- Pertussiveness
- Dyspnea
- Dizziness
- A headache
- Stomach pain
Rarely, more major side effects can develop. If you have any of the following, stop using Piperazine and get right back to your doctor:
- Convalescence
- Strong allergic responses (such as a rash, itching, or swelling)
- Liver issues, including jaundice, black urine, and stomach discomfort
- kidney issues (such as edema or lower urine output)
Piperazine Contraindications
Piperazine isnt fit for everyone. Tell your doctor about any medical problems you have, including:
- Pregnancy: Unless quite required, piperazine is not advised for use during pregnancy. Your doctor should thoroughly go over the risks and rewards with you.
- Breastfeeding: Piperazine is not advised for usage during breastfeeding unless absolutely required. Your doctor should thoroughly go over the hazards and advantages with you.
- renal disease: Piperazine should be taken carefully in those suffering from renal illness. One should advise close observation of renal performance.
- liver illness: Piperazine should be used carefully in those suffering from liver illness. One should advise close observation of liver performance.
- seizure disorders: Piperazine should be taken carefully in those suffering from seizure disorders. One should pay close attention.
- Known allergy: Should you have a known allergy to piperazine or any other component in the drug, you should not use piperazine.
Tell your doctor about all additional drugs you use, including vitamins, over-the-counter drugs, and herbal supplements. Certain drugs might interact with Piperazine and raise side effects likelihood.
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