ATC code | M04AA01 |
---|---|
CAS Number | 315-30-0 |
Other product names | Zyloprim, Lopurin, Aloprim |
Dosage form | Tablet |
Active ingredient | Allopurinol |
Other ingredients | Lactose monohydrate, maize starch, povidone, sodium starch glycolate, magnesium stearate |
Pharmacological classification | Antigout agents, Antihyperuricemic agents |
Pharmacological action | Inhibits xanthine oxidase, decreases blood uric acid |
Storage conditions | Store at room temperature, between 15 and 30 degrees Celsius |
What is Allopurinol?
Medication used to treat hyperuricemia—a disorder marked by elevated uric acid levels in the body—allopurinol is Along with kidney stones and other health issues, high uric acid can cause gout, a painful kind of arthritis. Allopurinol acts by preventing the bodys uric acid synthesis.
Allopurinol’s Components
Each tablet of this medication carries 100 mg of allopurinol. Additionally included are inactive components, including lactose, flour, polyvidone, talc, magnesium stearate, and sodium amylopectin glycolate.
Benefits and Effects of Allopurinol
Effective in lowering uric acid levels in the blood, allopurinol can help avoid gout episodes and other consequences related to hyperuricemia. In those with a history of kidney stones, it can also help stop kidney stones from forming.
What is Allopurinol Used For?
Mostly used to treat gout, a disorder marked by excruciating joint inflammation brought on by uric acid crystal accumulation, allopurinol is also used to prevent some forms of kidney stones and tumor lysis syndrome, a disorder brought on after cancer treatment.
How to Use Allopurinol
Usually taken once a day, take one mouthful of allopurinol, together with a full glass of water. You ought to have it following a dinner. The state of the person and the degree of their symptoms determine the allopurinol dosage. Your doctor will decide on your proper dosage.
Dosage and Administration
Until a serum uric acid level of 6 mg/dL or below is obtained, the first advised dosage for the therapy of gout is 100 mg orally daily, with weekly increases of 100 mg. Starting therapy with smaller dosages and titrating gradually lowers the incidence of gout flares and drug-induced major side effects.
Potential Side Effects of Allopurinol
Allopurinol has side effects, just like other drugs. Some typical side effects consist of:
- Not feeling well
- Pertussiveness
- Vaginal diarrhea
- Rash; stomach discomfort
- Aching
- Motionlessness
- Pain in the head
Rarely, allopurinol may have more major side effects, including:
- Severe allergic response
- Hepatic issues
- Kidney disorders
Should you have any major negative effects, you should stop using allopurinol right away and see your doctor.
Contraindications for Allopurinol
Not everyone will find allopurinol appropriate. If you are allergic to either allopurinol or any of the inactive components in this drug, you should not take it.
- Suffer from serious kidney issues.
- Experience extreme liver issues.
- Stow illnesses
Store allopurinol tablets dry, at room temperature, between 68°F and 77°F (20°C and 25°C). Keep allopurinol out of pets and childrens reach.
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