Ambrobene pills 30mg, 20pcs

Composition

1 table. contains:

Active ingredient:  

ambroxol hydrochloride 30 mg;

Auxiliary substances:  

lactose; 

corn starch,

magnesium stearate,

silicon dioxide highly dispersed

Pharmacological action

Ambrobene refers to chemical preparations that have an expectorant and sputum-diluting effect. The drug has a therapeutic effect in diseases with cough and difficult sputum discharge. The main active ingredient is ambroxol.

Ambrobene also has an antioxidant effect: it neutralizes and removes damaging molecules called free radicals from the body. The drug reduces the viscosity of sputum and facilitates its outflow from the bronchi.

Ambrobene acts as follows:

• the drug stimulates the production of enzymes in the bronchial mucosa that break down the bonds between substances that make up sputum; 
• activates the formation of surfactant (a mixture of active substances that prevent lung alveoli from sticking together);
• activates the function of cilia of the bronchial mucosa, preventing them from sticking together.

Indications

For the treatment of chronic and acute respiratory diseases in which sputum is present and its discharge from the respiratory tract is disturbed: pneumonia, bronchitis with difficulty in sputum discharge, bronchial asthma, bronchiectatic disease.

Use during pregnancy and lactation

Pregnancy:

There are insufficient data on the use of ambroxol during pregnancy. In particular, this applies to the first 28 weeks of pregnancy. Studies conducted on animals did not reveal a teratogenic effect.

The use of Ambrobene during pregnancy (II-III trimester) is possible only as prescribed by a doctor, after careful assessment of the risk / benefit ratio.

Breast-feeding period:

Animal studies have shown that ambroxol penetrates into breast milk. Due to insufficient research on the use of the drug in women during lactation, the use of Ambrobene is possible only as prescribed by a doctor, after careful assessment of the risk / benefit ratio.

Contraindications

• individual intolerance to any component of the drug; 
• peptic ulcer of the stomach and duodenum; 
• epilepsy and convulsive syndrome;
• functional insufficiency of the liver and kidneys;
• sputum production in large quantities and impaired bronchial motility due to immobile cilia (due to the threat of sputum stagnation in the bronchi).

Side effects

General violations: Rarely (from > 0.1% to >Very rare (

From the gastrointestinal tract: Rarely (from > 0.1% to >

Other services: Rarely (from > 0.1% to >

Interaction

With the simultaneous use of ambroxol and antitussive agents, due to the suppression of the cough reflex, stagnation of secretions may occur. Therefore, such combinations should be chosen with caution.

When ambroxol is co-administered with antibiotics amoxicillin, cefuroxime, erythromycin and doxycycline, the concentration of the latter in sputum and bronchial secretions increases.

The introduction of ambroxol (pH 5) should not be combined with the introduction of other solutions with a pH greater than 6.3, since the difference between the pH values of the solutions can lead to precipitation of the ambroxol base.

How to take, course of use and dosage

Inside, after eating, swallowing whole, without chewing, with plenty of liquid.

Children from 6 to 12 years old:  1/2 tablet 2-3 times a day (15 mg ambroxol 2-3 times a day).

Adults and children over 12 years of age:  in the first 2-3 days of treatment-1 tablet 3 times a day (30 mg ambroxol 3 times a day).

If the therapy is ineffective, adults can increase the dose to 2 tablets. 2 times a day (120 mg ambroxol per day).

In the following days,1 tablet should be taken. 2 times a day (30 mg ambroxol 2 times a day).

Overdose

Symptoms:  there were no signs of intoxication with an overdose of ambroxol. There are reports of nervous excitement and diarrhea.

Ambroxol is well tolerated when taken orally at a dose of up to 25 mg / kg / day.

In case of severe overdose, increased salivation, nausea, vomiting, and a decrease in blood pressure are possible.

Treatment:  intensive care methods, such as inducing vomiting, gastric lavage, should be used only in cases of severe overdose, in the first 1-2 hours after taking the drug. Symptomatic treatment is indicated.

Special instructions

It should not be combined with antitussive medications that make it difficult to remove sputum.

Extremely rarely, severe skin reactions such as Stevens-Johnson syndrome and Lyell’s syndrome have been observed with Ambrobene.

If the skin or mucous membranes change, you should immediately consult a doctor and stop taking the drug.

The impact on the ability to drive vehicles and control machines and mechanisms is still unknown.

Form of production

Tabletooks

Storage conditions

Store in a dark place at a temperature not exceeding 25°C.

Shelf life

5 years

Active ingredient

Ambroxol

Dosage form

Tablets

Description

For adults, Children over 6 years of age, Children as prescribed by a doctor, Pregnant women in the second and third trimester as prescribed by a doctor

Indications

Cough, Cold, Pneumonia, Bronchitis, Flu, Chronic Obstructive Pulmonary Disease, Bronchial asthma