Amixin, pills 125mg, 6pcs

Composition

1 tablet contains Tiloron 125 mg,

excipients:  

magnesium carbonate,

polyvinylpyrrolidone,

calcium stearate, aerosil,

petrolatum oil,

sugar,

talc,

tropeolin O,

titanium dioxide,

gelatin,

beeswax.

Pharmacological action

Pharmaceutical group:

antiviral immunostimulating agent-inducer of interferon formation.

Pharmaceutical effect:

Amixin is a low-molecular-weight synthetic interferon inducer that stimulates the formation of interferons alpha, beta and gamma in the body. The main producers of interferon in response to the introduction of tiloron are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils and granulocytes. After oral use, the maximum interferon production is determined in the gut-liver-blood sequence after 4-24 hours.

Amixin® has an immunomodulatory and antiviral effect.

In human leukocytes, it induces the synthesis of interferon. It stimulates bone marrow stem cells, increases antibody formation depending on the dose, reduces the degree of immunosuppression, and restores the ratio of T-suppressors and T-helpers.

It is effective against various viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis viruses and herpesviruses. The mechanism of antiviral action is associated with the inhibition of translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed.

Pharmacokinetics:

After oral use, it is rapidly absorbed from the gastrointestinal tract. Bioavailability — 60%. About 80% of the drug binds to plasma proteins. The drug is excreted almost unchanged through the intestines (70%) and through the kidneys (9%). The elimination half-life (T1 / 2) is 48 hours. The drug does not undergo biotransformation and does not accumulate in the body.

Indications

In adults, treatment and prevention of influenza, other respiratory treatment of viral hepatitis, A, b and C; treatment of herpes and cytomegalovirus infection;

in the complex therapy of infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, avioanele, etc. ),

in the complex therapy of urogenital and respiratory chlamydia, in the treatment of pulmonary tuberculosis;

In children over 7 years of age — for the treatment of influenza and other acute respiratory infections.

Contraindications

• Children under 7 years of age.
• Pregnancy.
• The period of lactation (breastfeeding).
• Hypersensitivity to the drug.

Side effects

From the digestive system: Possible symptoms of dyspepsia.

Other services: Possible short-term chills. Allergic reactions.

Interaction

Amixin is compatible with antibiotics and traditional treatments for viral and bacterial infections.

How to take, course of use and dosage

The drug is taken orally after a meal.

Non-specific prevention of viral hepatitis A in adults for non-specific prevention of viral hepatitis A, the drug is prescribed at a dose of 125 mg once a week for 6 weeks. The course dose is 750 mg (6 tablets).

Treatment of viral hepatitis A In the treatment of viral hepatitis A, the dose of the drug on the first day is 125 mg 2 times / day, then switch to taking 125 mg after 48 hours. The course of treatment is 1.25 g (10 tablets).

Treatment of acute hepatitis B In the treatment of acute hepatitis B in the initial phase of treatment on the first and second days, the dose of the drug is 125 mg/day, and then 125 mg after 48 hours. The course of treatment is 2 g (16 tablets).

Prolonged course of hepatitis In case of prolonged course of hepatitis B on the first day, the dose of the drug is 125 mg 2 times / day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets).

Chronic hepatitis B In case of chronic hepatitis B in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the daily dose is 250 mg, then switch to taking 125 mg after 48 hours. In the continuation phase of treatment, the total dose is from 1.25 g (10 tablets). up to 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amixin varies from 3.75 to 5 g, the duration of treatment is 3.5-6 months, depending on the results of biochemical, immunological and morphological studies that reflect the degree of activity of the process.

Acute hepatitis C In acute hepatitis C, on the first and second days of treatment, Amixin is prescribed at a dose of 125 mg/day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets).

Chronic hepatitis C With chronic hepatitis C in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the drug is taken at a dose of 250 mg / day, then 125 mg after 48 hours. In the continuation phase of treatment, the total dose is 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amixin is 5 g (40 tablets), the duration of treatment is 6 months, depending on the results of biochemical, immunological and morphological studies that reflect the degree of activity of the process.

Complex therapy of neuroviral infections

In complex therapy of neurovirus infections – 125-150 mg / day in the first two days of treatment, then 125 mg after 48 hours. The dose is set individually, the duration of the course of treatment is 3-4 weeks.

Treatment of influenza and other acute respiratory infections For the treatment of influenza and other acute respiratory infections in the first 2 days of the disease, Amiksin is prescribed at a dose of 125 mg/day, then 125 mg after 48 hours. The course dose is 0.75 g (6 tablets).

Prevention of influenza and ARVI For the prevention of influenza and ARVI, Amixin is prescribed at a dose of 125 mg once a week for 6 weeks. The course dose is 750 mg (6 tablets).

Treatment of herpetic and cytomegalovirus infections.

For the treatment of herpetic, cytomegalovirus infection, the dose of the drug in the first 2 days is 125 mg, then 125 mg is taken after 48 hours. The course dose is 1.25-2.5 g (10-20 tablets).

Urogenital and respiratory chlamydia In urogenital and respiratory chlamydia, Amixin is prescribed at a dose of 125 mg/day for the first 2 days, then 125 mg after 48 hours. The course dose is 1.25 g (10 tablets).

Complex therapy of tuberculosis In the complex therapy of pulmonary tuberculosis in the first 2 days, the drug is prescribed 250 mg/day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets).

Appointment for children over 7 years of age with uncomplicated forms of influenza and other acute respiratory viral infections

For children over 7 years of age with uncomplicated forms of influenza or other acute respiratory viral infections, the drug is prescribed at a dose of 60 mg (1 tab. ) 1 time/day after meals on the 1st,2nd and 4th day from the start of treatment. The course dose is 0.18 g (3 tablets).

Development of complications of influenza and other acute respiratory viral infections. With the development of complications of influenza and other acute respiratory viral infections, the drug is taken at 60 mg 1 time/day on the 1st,2nd,4th,6th day from the start of treatment. The course dose is 0.24 g (4 tablets).

Form of production

Coated tablets.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 30 °C

Shelf life

3 years

Active ingredient

Tiloron

Dosage form

Tablets

Description

For adults

Indications

Chlamydia, Hepatitis, Flu and cold prevention, Tuberculosis, Cold, Herpes, Flu, Cytomegalovirus infection