Apisarthron, ointment, 20g

Composition

100 g of the drug contains: Active ingredients: Bee venom – 3.0 mg;Methyl salicylate – 10.0 g;Allylisothiocyanate – 1.0 g. Auxiliary substances: sodium lauryl sulfate-0.7 g; white vaseline-6.0 g; emulsified cetostearyl alcohol-14.0 g, which contains: sodium cetyl stearyl sulfate-1.4 g, cetostearyl alcohol-12.6 g; water – up to 100 g.

Pharmacological action

Combined medicinal product for external use based on highly purified bee venom. Bee venom has analgesic and anti-inflammatory effects (stabilizes lysosomal membranes), shows an antibacterial effect (inhibits the growth of gram-positive bacteria). Methyl salicylate belongs to the group of nonsteroidal anti-inflammatory drugs, has a pronounced anti-inflammatory effect (inhibits the production of prostaglandins, inhibits cyclooxygenase). Allylisothiocyanate (purified standardized mustard oil extract) causes deep tissue warming, improves local blood flow, and reduces muscle tonic contraction.

Indications

• of Disease of the peripheral nervous system, accompanied by a feeling of pain, neuralgia, neuritis, radiculitis, pain in the lumbar region (sciatica);

• muscle pain (myalgia) and soft tissue damage, including injury;

• warm up muscles before, during and after physical activity and sports;

• damaged/strain injuries, accompanied by pain and swelling;

• diseases of musculoskeletal system (osteoarthritis, rheumatic soft tissue), degenerative-dystrophic lesions and pain in the joints.

Contraindications

• Hypersensitivity to bee venom, salicylates, isothiocyanate;
• severe chronic renal failure;
• liver failure;
• skin diseases;
• neoplasms;
• skin damage;
• acute arthritis;
• infectious diseases;
• suppression of bone marrow hematopoiesis;
• mental illnesses;
• childhood (up to 6 years);
• pregnancy and lactation.

Side effects

In rare cases, allergic skin reactions and irritation at the application site are possible.

Interaction

Methylsalicylate enhances the effect of anticoagulants, methotrexate.

How to take, course of use and dosage

Externally.

A strip of ointment 3-5 cm long is evenly distributed on the skin (the layer thickness is approximately 1 mm) until redness and a feeling of warmth appear (2-3 minutes).

After that, slowly and intensively rub the ointment into the skin. To enhance the therapeutic effect, it is recommended to keep the treated areas warm.

Apply 2-3 times a day until symptoms disappear (no more than 10 days).

Overdose

Data on overdose of Apizartron were not provided.

Description

Ointment from white to slightly yellowish color, uniform consistency with the smell of methyl salicylate.

Special instructions

The drug should not be applied to damaged and irritated skin, as well as on areas affected by skin diseases.

In patients with renal insufficiency, Apizartron should not be used on large skin surfaces for a long time.

Avoid contact of the ointment with eyes, mucous membranes and open wounds.

Form of production

Ointment for external use.

Storage conditions

Store at a temperature not exceeding 25°C. Keep out of reach of children!

Shelf

life is 3 years.

Active ingredient

Methyl salylate, Bee venom

Dosage form

ointment

Description

For athletes, Adults, and Children over 6 years of age

Indications

Osteoarthritis, Sciatica, Arthritis, Osteoarthritis, Neuritis, Sciatica, Muscle warming before Sports exercises, Trigeminal Neuralgia