Basiron AC, gel 5%, 40g

Composition

>of 1 g of gel contains 50 mg of benzoyl peroxide. Auxiliary substances: Acrylate copolymer; Poloxamer 182; Carbomer 940 (carbopol 980); Glycerin;Disodium edetate; Sodium dioctyl sulfosuccinate;Propylene glycol;Colloidal anhydrous silicon; Sodium hydroxide; Distilled water.

Pharmacological action

Baziron AC has a high antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis, has a comedonolytic and anti-inflammatory effect, improves tissue oxygenation, suppresses sebum production in the sebaceous glands, absorbs excess sebaceous secretions and moisturizes the skin. Benzoyl peroxide, being a powerful oxidizing agent, has a strong bactericidal effect on microorganisms; however, microorganisms are not able to produce strains resistant to benzoyl peroxide. In vivo studies based on the results of inoculation showed that 94% inhibition of the growth of Propionibacterium acnes culture was observed on day 7, and 97-99% on day 15. The anti-inflammatory effect of benzoyl peroxide is based on the inactivation of free radicals in the focus of inflammation and the inhibition of free fatty acids. The base of the preparation is represented by the acrylate copolymer/glycerin complex; this ensures controlled adsorption of excess sebum and gradual release of glycerol to soften and moisturize the skin.

Indications

Acne.

Use during pregnancy and lactation

It is not recommended to use the drug Baziron AS during pregnancy and lactation.

Recommendations for use

The gel should be applied to a clean and dry surface of the affected skin 1 or 2 times a day (morning or evening). The course of treatment is 3 months. The therapeutic effect develops 4 weeks after the start of the drug. Persistent improvement occurs after 3 months of therapy. Baziron AC is indicated for the treatment of mild to moderate acne with a predominance of pustular elements as monotherapy, and for moderate acne also in combination with other local (retinoids) and systemic (antibiotics, oral antiandrogens). If necessary, it is possible to conduct a second course of treatment.

Contraindications

-children under 12 years of age; – hypersensitivity to the components of the drug.

Interaction

There are currently no data on the drug interaction of the drug Baziron AS, used according to indications and in recommended doses, with other drugs for external and systemic use.

Overdose

Symptoms:  if a large amount of the drug is accidentally applied to the skin, severe irritation may occur at the application site. Treatment:  the drug should be discontinued and symptomatic therapy should be performed.

Special instructions

-If skin irritation occurs after applying the gel, Baziron AS should be discontinued. -It is not recommended to apply the gel to areas of the skin with damage to the integrity of the skin. -If the drug accidentally gets on the mucous membrane of the eyes, mouth or nose, rinse it thoroughly with warm water. -During the period of application of the drug, avoid direct sunlight on the site of its application, as this may cause skin irritation. – During the application of Baziron AC, the simultaneous use of drying or irritating agents (perfumes or ethanol-containing products) is not recommended.

Form of production

Gel for external use 5%

Storage conditions

The drug should be stored at a temperature not exceeding 25°C. temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Benzoyl Peroxide

Dosage form

gel for external use

Description

Children over 12 years old, For adults

Indications

Acne