Belosalic, lotion solution for external use in dropper bottle 50ml

Composition

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of 1 g of the solution contains:

Active ingredients:

betamethasone dipropionate – 640 mcg, which corresponds to the content of betamethasone-500 mcg;

salicylic acid-20 mg.

Auxiliary substances:

disodium edetate-0.3 mg,

hypromellose 4000 sPz-5 mg,

sodium hydroxide-5 mg,

isopropanol-392 mg,

water-577.06 mg

Pharmacological action

Pharmaceutical group:

glucocorticosteroid+keratolytic agent.

Pharmaceutical action:

 Preparation for external use. Belosalic ® lotion has anti-inflammatory, antipruritic, decongestant, anti-allergic, antiproliferative, immunosuppressive, keratolytic, antimicrobial, antifungal effects.

Betamethasone dipropionate is a synthetic corticosteroid that has anti-inflammatory, anti-allergic, antipruritic and vasoconstrictor effects.

When applied to the skin surface, it narrows blood vessels, relieves itching, reduces the release of inflammatory mediators (from eosinophils and mast cells), interleukins 1 and 2, gamma interferon (from lymphocytes and macrophages), inhibits the activity of hyaluronidase and lowers the permeability of the vascular wall.

It interacts with specific receptors in the cytoplasm of the cell, stimulates the synthesis of mRNA, which induces the formation of proteins, including lipocortin, mediating cellular effects. Lipocortin inhibits phospholipase A2, blocks the release

of arachidonic acid and the biosynthesis of endoperoxides, prostaglandins, and leukotrienes (which contribute to the development of inflammation, allergies, and other pathological processes).

Salicylic acid due to its keratolytic action cleanses the affected areas from scales, promotes the penetration of betamethasone into the skin, supports the acidic environment of the skin, preventing the development of bacterial and fungal infections.

Indications

Subacute and chronic dermatoses that are sensitive to corticosteroid therapy and are accompanied by hyperkeratosis and peeling:

• Psoriasis.
• Seborrhea.
• Seborrheic dermatitis (of the scalp).
• Asbestos-like lichen.
• Neurodermatitis.
• Red lichen planus with localization on the scalp.
• Eczema.
• Skin dyshidrosis.
• Ichthyosis.

Use during pregnancy and lactation

The use of Belosalic ® lotion in pregnant women is allowed in cases where the intended benefit to the mother exceeds the risk to the fetus. In such cases, the use of the drug should be short and limited to small areas of the skin.

During breastfeeding, the use of the drug Belosalic ® lotion is possible according to strict indications, but the drug should not be applied to the skin of the breast before feeding.

Contraindications

• Tuberculosis of the skin.
• Skin manifestations of syphilis.
• Chicken pox.
• Viral skin infections.
• Skin postvaccinal reactions.
• Open wounds.
• Trophic ulcers.
• Rosacea.
• Vulgar blackheads.
• Children under 6 months of age.
• Hypersensitivity to betamethasone, salicylic acid or any of the auxiliary components of the drug.

Side effects

Side effects are usually reversible and mild in nature.

From the side of the skin:  hypersensitivity reactions (itching, burning, hyperemia), acne-like changes, hypopigmentation, striae, skin atrophy, hypertrichosis, and secondary skin infections may occur.

With prolonged continuous uncontrolled use and when applied to large areas of the skin:  telangiectasia, systemic manifestations of side effects of corticosteroids or salicylates.

If a hypersensitivity reaction or adverse reactions develop, the drug should be discontinued and a doctor should be consulted.

Interaction

There was no clinically significant interaction with other drugs.

Simultaneous use of cosmetic and dermatological products for external use containing ethanol, or medical soap with a pronounced drying effect, can cause skin irritation.

How to take, course of use and dosage

The drug is intended for external use.

A few drops of the solution for external use are evenly distributed over the surface of the skin, lightly rubbing. The frequency of application is 2 times / day, in mild cases, a single use is sufficient.

The duration of a continuous course of treatment is usually limited to 3-4 weeks. If you need a longer course of therapy, it is recommended to use the drug less often, for example, every other day.

The drug can be prescribed with caution to children from 6 months and for the shortest possible time.

Overdose

Symptoms:  manifestation of systemic side effects.

Treatment:  discontinuation of the drug and symptomatic therapy are recommended.

Special instructions

The drug is intended for external use only.

Avoid contact with the eyes and mucous membranes, as well as the use of the drug in the anogenital area.

It is not recommended to use the drug under an occlusal dressing, except when necessary.

If fungal or bacterial microflora develops on the skin, additional use of an antibacterial or antifungal agent is necessary.

The preparation Belosalic ® lotion in the form of a solution for external use is especially convenient for use on the scalp. The solution is easily distributed over the surface of the skin, does not stick or dry the hair, does not leave visible traces, and has a cooling effect on the skin.

Influence on the ability to drive motor vehicles and manage mechanisms

There are no data on the adverse effects of Belosalic ® lotion on the ability to drive vehicles and mechanisms.

Form of production

Solution for external use.

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

2 years

Active ingredient

Betamethasone, Salicylic Acid

Description

Pregnant women as prescribed by a doctor, Children as prescribed by a doctor, Children older than 6 months, For adults, Nursing mothers as prescribed by a doctor

Indications

Psoriasis, Allergies, Neurodermatitis, Dermatitis, Eczema, Urticaria, Dermatosis