Enterofuryl, 200mg/5ml suspension, 90ml

Product description

Enterofuril® is a drug for the initial treatment of intestinal infections. Eliminates the cause of diarrhea-harmful microbes and bacteria. It works only in the intestinal lumen. Preserves the normal intestinal microflora. Prevents the development of bacterial complications in viral diarrhea.

Composition

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of 5 ml of suspension for oral use contains:

Active ingredient:  

nifuroxazide 200 mg,

excipients:  

sucrose-1000 mg;

sodium hydroxide-2 mg;

methyl parahydroxybenzoate-5 mg;

ethanol 96% – 0.05 ml;

carbomer-10.5 mg;

citric acid-0.75 mg;

banana flavor-10 mg;

water-up to 5 ml

Pharmacological action

Enterofuril® is a broad-spectrum antimicrobial drug that does not have a systemic effect and is used to treat diarrhea of infectious etiology. Enterofuril®contains the Active ingredient nifuroxazide, a drug of the 5-nitrofuran derivative group. The drug has a bactericidal and bacteriostatic effect against most pathogens of acute intestinal infections. The antimicrobial effect of nifuroxazide is dose-dependent: for example, low and medium doses of the drug have a bacteriostatic effect on pathogenic microflora, and high doses have a bactericidal effect. The bacteriostatic mechanism of action of the drug is associated with inhibition of the activity of the dehydrogenase enzyme, which leads to a violation of the normal course of synthesis of vital compounds in the cell of the microorganism. Thus, due to the effect of nifuroxazide on the cell of the microorganism, there is a violation of the respiratory chain, inhibition of the tricarboxylic acid cycle. In addition, Enterofuril inhibits protein synthesis in the microbial cell and inhibits other biochemical processes in the bacterial cell. Thus, the cell of the microorganism loses its ability to reproduce.

Indications

Diarrhea of bacterial origin, chronic lesions of the gastrointestinal tract of bacterial etiology, accompanied by dyspeptic phenomena.

Use during pregnancy and lactation

The use of Enterofuril during pregnancy is possible only in cases where the expected benefit of therapy for the mother exceeds the potential risk to the fetus.

Enterofuril is not absorbed from the gastrointestinal tract and does not enter the systemic circulation, but the use of the drug during lactation is possible only for strict indications, and the question of stopping breastfeeding should be decided.

Contraindications

-Hypersensitivity to nitrofuran derivatives or other components of the drug; – fructose intolerance, glucose-galactose malabsorption syndrome or sucrose and isomaltase insufficiency;- newborn period (up to 1 month), prematurity.

Side effects

Allergic reactions (rash, urticaria, angioedema, anaphylactic shock), nausea, vomiting.

How to take, course of use and dosage

Inside. Nifuroxazide therapy should not be continued for more than 7 days. For dosing, a dosage spoon with a volume of 5 ml is used, which has a graduation of 2.5 ml. The suspension should be shaken well before use. Children 1-6 months: 2.5 ml 2-3 times a day (with an interval of 8 to 12 hours). Children 7 months-2 years: 2.5 ml 4 times a day (with an interval of 8 hours). Children 3-7 years: 5 ml 3 times a day (with an interval of 8 hours). Adults and children over 7 years of age: 5 ml 3-4 times a day (at intervals of 6-8 hours).

Overdose

The drug is not absorbed from the gastrointestinal tract and does not enter the systemic circulation.

Symptoms of overdose are not known.

If the dose is exceeded, gastric lavage and symptomatic treatment are recommended.

Special instructions

When treating diarrhea simultaneously with nifuroxazide therapy, rehydration therapy (oral or intravenous) should be performed according to the patient’s condition and the intensity of diarrhea.

The use of alcohol during nifuroxazide therapy is prohibited.

Before prescribing the suspension to infants, it is necessary to exclude their congenital deficiency of sucrose-breaking enzymes.

Influence on the ability to drive vehicles and work with mechanisms

The drug does not affect psychomotor activity and the ability to drive vehicles and work with mechanisms.

Form of production

Suspension for oral use.

Storage conditions

At a temperature not exceeding 30 °C (do not freeze).

Shelf

life is 3 years.

Active ingredient

Nifuroxazide

Dosage form

suspension for oral use

Description

Children older than 1 month, Nursing mothers as prescribed by a doctor, For adults

Indications

Diarrhea, Salmonellosis, Intestinal Infections, Poisoning