Floxal, eye ointment 3mg/g 3g

Composition

of 1 g-ofloxacin 3 mg

Auxiliary substances:

liquid paraffin-100 mg,

wool fat-50 mg,

white vaseline-847 mg

Pharmacological action

Ofloxacin is an antimicrobial drug from the group of broad-spectrum fluoroquinolones.

The bactericidal effect of ofloxacin is associated with the blockade of the DNA gyrase enzyme in bacterial cells.

Highly active against most gram-negative microorganisms: Esherichia coli, Salmonella spp., Proteus spp, Morganella morganii, Shigella spp., Klebsiella spp. Enterobacter spp, Serratia spp, Citrobacter spp, Yersinia spp, Providencia spp, Haemopilus influenzae, Neisseria gonorrhoeae, Neisseria menigitidis, Mycoplasma spp., Legionella pneumophila, Acinetobacter spp, Chlamydia spp.

It is active against some strains of Gram-positive microorganisms, in particular Staphylococcus spp., Streptococcus spp.

Enterococcus faecalis, Streptococcus pneumoniae, and Pseudomonas spp. are moderately sensitive to ofloxacin.

Ofloxacin acts on microorganisms that produce beta-lactamase.

Anaerobic bacteria (except B. Urealiticus) are not sensitive to the drug.

Pharmacokinetics

When applied topically, the therapeutic concentration of the drug in the eye tissues is achieved.

Indications

Infectious and inflammatory diseases of the anterior eye caused by microorganisms sensitive to ofloxacin:

• blepharitis, barley, conjunctivitis, dacryocystitis, keratitis, corneal ulcer,
• chlamydia infection of the eye,
• prevention and treatment of bacterial infection after eye injuries and surgical interventions.

Use during pregnancy and lactation

There are no data on the negative effect of ofloxacin on the fetus, but the drug is contraindicated for use during pregnancy and lactation (breastfeeding).

Contraindications

• hypersensitivity to any of the components;
• pregnancy and lactation

Side effects

Possible: allergic reactions, transient conjunctival hyperemia, burning sensation, eye discomfort, itchy and dry conjunctiva, photophobia, lacrimation.

Rare: dizziness.

Interaction

Drug interaction of the drug Floxal is not described.

How to take, course of use and dosage

1.5 cm strips of ointment are placed behind the lower eyelid of the affected eye 2-3 times/day;

in the case of chlamydia infection – 5 times/day. It is not recommended to use the drug for more than 2 weeks.

If more than one preparation is used simultaneously, the ointment should be used last.

Overdose

There are no data on overdose with Floxal.

Special instructions

It is not recommended to wear contact lenses while using the drug

Avoid prolonged exposure to bright light and wear sunglasses (due to possible photophobia).

Influence on the ability to drive motor vehicles and manage mechanisms

In case of visual disturbances associated with instillation of eye drops or application of ointment, patients should refrain from potentially dangerous activities until the undesirable phenomena disappear.

Form of production

Eye ointment is uniform, light yellow in color.

Storage conditions

The drug should be stored in a place protected from light at a temperature not exceeding 25°C.

Shelf

life is 3 years. After opening the tube – 6 weeks.

Active ingredient

Ofloxacin

Conditions of release from pharmacies

By prescription

Dosage form

ointment

Description

For adults as directed by your doctor

Indications

Barley on the eye, Eye Infections, Inflammatory eye diseases, Blepharitis, Conjunctivitis