Galidor, solution 25mg/ml 2ml ampoules 10pcs

Composition

1 amp. contains bencyclane fumarate 50 mg

Pharmacological action

Pharmacological action-myotropic antispasmodic, vasodilating.

Pharmacodynamics

Bencyclane is a myotropic antispasmodic with a pronounced vasodilating effect. The vasodilating effect of bencyclane is mainly associated with its ability to block calcium channels, antiserotonin action, and to a lesser extent — with the blockade of sympathetic ganglia.

In addition, bencyclane has an antispasmodic effect on the visceral muscles (gastrointestinal tract, genitourinary organs, respiratory organs). The drug causes a slight increase in heart rate. Its weak tranquilizing effect is also known.

Bencyclane can cause dose-dependent suppression of Na+ / K+-dependent ATPase and platelet and red blood cell aggregation, as well as an increase in red blood cell elasticity. These effects are mainly observed in peripheral vessels, coronary arteries, and brain vessels.

Indications

• biliary dyskinesia, stomach and intestinal spasms
• biliary colic, cholecystitis, renal colic.

Use during pregnancy and lactation

Application Galidor is possible according to indications.

Contraindications

• renal failure
• severe liver function
• disorders cardiac arrhythmias.

Side effects

• dizziness, headache
• general weakness, drowsiness
• dry mouth, nausea, decreased appetite, diarrhea
• rapid heartbeat
• decreased white blood cell
• count allergic reactions.

Interaction

Caution should be exercised when combined with the following products:  

• anesthetics and sedative effects may increase;
• drugs for General anesthesia – strengthening their actions; a sympathomimetic agents – because of the risk of atrial and ventricular tachyarrhythmias;
• a means of reducing the level of blood potassium and quinidine – due to the possible summation pruritogens effects
• of digitalis drugs increases the risk of arrhythmias in overdose of digitalis;
• beta-blockers – because opposites chronotropic effects (from a negative beta-blockers and positive bencyclane) you may need to adjust the dosage of a beta-blocker;
• the calcium channel blockers and other antihypertensive agents – because of the ability to enhance their effect;
• drugs that cause side effects in the form of spazmofilii – because of the possibility of summation of these effects;
• acetylsalicylic acid due to increased inhibition of platelet aggregation.

How to take, course of use and dosage

Parenterally, the drug is administered intravenously in a jet (after dilution) or infusion.

The daily dose is 200 mg divided into 2 injections.

Overdose

Symptoms:  increased heart rate, decreased blood pressure, collapse, urinary incontinence, drowsiness, anxiety, and in severe cases – epileptiform seizures. A significant overdose can cause tonic-clonic seizures.

Treatment:  The specific antidote is not known. In case of overdose, the stomach should be washed and symptomatic treatment should be prescribed. There are no data on the possible elimination of bencyclane by dialysis.

Special instructions

Concomitant use of Halidor with sedatives leads to increased drowsiness.

Form of production

Solution for intravenous and intramuscular use

Storage conditions

The drug should be stored out of the reach of children at a temperature of 15° to 25°C.

Shelf

life is 5 years.

Active ingredient

Bencyclane

Conditions of release from pharmacies

By prescription

Dosage form

solution for injection and infusion

Description

For adults as directed by your doctor

Indications

Cholelithiasis, Raynaud’s disease, Spasm of the gastrointestinal tract, Gastric ulcer and duodenal ulcer, Colitis, Cholecystitis, Urolithiasis