Gynofort, vaginal cream 20mg/g, 5g

Composition

Active ingredient:

butoconazole nitrate 20 mg;

Excipients:

sorbitol — 399,78 mg;

oil mineral 80,32 mg;

glyceryl monostearate — 27,13 mg;

polyglyceryl-3-oleate — 27,13 mg;

wax — of 4.52 mg;

silicon dioxide colloidal — 10,13 mg;

disodium edetate — 0.5 mg;

methyl parahydroxybenzoate and 1.8 mg;

parahydroxybenzoate — 0.5 mg;

propylene glycol,50 mg;

water — 378,19 mg

Pharmacological action

Ginofort has fungicidal activity against fungi Candida, Trichophyton, Microsporum, Epidermophyton, and some Gram-positive bacteria. It is most effective for candidiasis.

Blocking the formation of ergosterol from lanosterol in the cell membrane increases the permeability of the membrane, which leads to lysis of the fungal cell.

The vaginal cream is a water-in-oil emulsion, so it gives the carrier of butoconazole a bioadhesive property (bioadhesion leads to an increase in the bioavailability and duration of action of the drug).

With intravaginal use, butoconazole is present on the vaginal mucosa for 4-5 days.

Indications

Vaginal candidiasis caused by Candida albicans.

Use during pregnancy and lactation

The drug is contraindicated during pregnancy and lactation.

Contraindications

• pregnancy;
• lactation;
• hypersensitivity to any of the components of the drug;
• children under 18 years of age (efficacy and safety have not been established).

Side effects

Burning, itching, soreness and swelling of the vaginal wall, pain/cramps in the lower abdomen.

Interaction

Ginofort ® cream contains mineral oil that damages latex or rubber products (including condoms or intravaginal diaphragms), so within 72 hours after applying Ginofort® it is not recommended to use the above-mentioned contraceptives. Other methods of contraception should be used.

How to take, course of use and dosage

Intravaginally.

Treatment consists of a single application of the contents of one applicator (about 5 g), inserted into the vagina at any time of the day.

If the symptoms of the disease persist, repeat the microbiological examination.

Product form

vaginal cream

Storage conditions

At a temperature of 15-25 °C.

Shelf life

3 years

Active ingredient

Butoconazole nitrate

Conditions of release from pharmacies

By prescription

Dosage form

vaginal cream

Description

Nursing mothers as prescribed by a doctor, Adults as prescribed by a doctor, Pregnant Women as prescribed by a doctor

Indications

Thrush, Fungus