Metrogyl Denta dental gel, 20g

Product description

Thanks to the powerful combination of chlorhexidine and metronidazole, Metrogyl Denta ® has antiseptic and antibacterial effects on a wide range of organisms that cause gum inflammation.

Composition

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of 1 g of gel contains:  

Active ingredients:  

Metronidazole benzoate – 16.0 mg (equivalent to metronidazole-10.0 mg) 

Chlorhexidine digluconate 20% solution-2.5 mg (equivalent to chlorhexidine digluconate-0.5 mg)

Auxiliary substances:

propylene glycol 50.0 mg,

carbomer-980 15.0 mg,

disodium edetate 0.5 mg,

saccharin 1.0 mg,

levomentol 5.0 mg,

sodium hydroxide 4.0 mg,

water up to 1 g

Pharmacological action

The effectiveness of the drug is due to the presence of two antibacterial components in its composition:  

a) metronidazole has an antibacterial effect against anaerobic bacteria that cause periodontal disease: Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium fusiformis, Wolinella recta, Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.

b) chlorhexidine – antiseptic and antibacterial agent, effective against gram-positive and gram-negative aerobic and anaerobic bacteria (Treponema spp., Neisseria gonorrhoeae, Trichomonas spp., Chlamydia spp. Ureaplasma spp. Bacteroides fragilis). Some strains of Pseudomonas spp., Proteus spp. are weakly sensitive to the drug, as well as acid-resistant forms of bacteria, bacterial spores. It does not interfere with the functional activity of lactobacilli.

When applied topically, Metrogyl Dent gel is practically not absorbed.

Indications

Infectious and inflammatory diseases of the periodontal and oral mucosa: – acute and chronic gingivitis;- acute ulcerative-necrotic gingivitis of Vincent; – acute and chronic periodontitis; – juvenile periodontitis;- periodontal disease complicated by gingivitis;- aphthous stomatitis;- cheilitis; – inflammation of the oral mucosa when wearing dentures;- post-extraction alveolitis (inflammation of the hole after tooth extraction);- periodontitis, periodontal abscess (as part of combination therapy).

Use during pregnancy and lactation

Due to the lack of clinical data, the safety of using the drug during pregnancy and lactation has not been established. It is not recommended to use the drug during pregnancy. During breastfeeding, if necessary, prescribe the drug should decide whether to stop breastfeeding.

Contraindications

• hypersensitivity to metronidazole, chlorhexidine, nitroimidazole derivatives or other components of the drug;
• diseases of the blood system, including in the anamnesis;
• diseases of the peripheral and central nervous system;
• children under 18 years of age.

Side effects

Topical application of Metrogyl Denta®, a dental gel, may cause allergic reactions (skin rash, pruritus, urticaria, anaphylactic reactions, including anaphylactic shock), as well as headache.

Interaction

When applied topically at the recommended doses, no systemic interaction of Metrogyl Denta ® gel with other drugs was detected.

How to take, course of use and dosage

Topically, for dental use only. When the gums become inflamed (gingivitis): Metrogyl Denta® is applied to the gum area in a thin layer with your finger or with a cotton swab 2 times a day. After applying the gel, you should refrain from drinking and eating for 30 minutes. It is not recommended to wash off the gel. The duration of treatment is on average 7-10 days. For periodontitis: after removing dental deposits, the periodontal pockets are treated with Metrogyl Denta® gel, and the gel is applied to the gum area. The exposure time is 30 minutes. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel independently. Metrogyl Denta® is applied to the gum area 2 times a day for 7-10 days. For aphthous stomatitis: Metrogyl Denta® is applied to the affected area of the oral mucosa 2 times a day for 7-10 days. To prevent exacerbations of chronic gingivitis and periodontitis: Metrogyl Denta ® gel is applied to the gum area 2 times a day for 7-10 days. Preventive treatment courses are conducted 2-3 times a year. To prevent post-extraction alveolitis: after tooth extraction, the hole is treated with Metrogyl Denta® gel, then the gel is applied 2-3 times a day for 7-10 days.

Overdose

Accidental or deliberate ingestion of a large amount of gel can lead to increased side effects, mainly due to metronidazole (chlorhexidine is practically not absorbed from the gastrointestinal tract). Nausea, vomiting, dizziness may occur, and in more severe cases, paresthesia and convulsions may occur. Treatment: gastric lavage, if necessary, symptomatic therapy.

Special instructions

The use of Metrogyl Denta® does not replace hygienic brushing of teeth, so during the course of treatment with the drug, tooth brushing should be continued. The drug should be kept out of the reach of children. If a child accidentally or intentionally swallows the drug, seek immediate medical attention. If the medicine has become unusable or expired, do not dispose of it in the waste water or on the street! Place the medicine in a plastic bag and put it in the trash can. These measures will help protect the environment!<

Form of production

Dental gel

Storage conditions

Store at a temperature not exceeding 25 °C out of the reach of children.

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

Metronidazole

Dosage form

dental gel

Description

Pregnant women in the second and third trimester as prescribed by a doctor, Children over 6 years of age, For adults

Indications

Stomatitis, Gum Disease, Periodontitis, Oral Inflammation, Periodontitis