ATC code | L04AA14 |
---|---|
CAS Number | 1214461-31-8 |
Other product names | Baricitinib |
Dosage form | Tablet |
Active ingredient | Baricitinib |
Other ingredients | Croscarmellose sodium, magnesium stearate, mannitol, microcrystalline cellulose, ferric oxide, lecithin (soya), polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide |
Pharmacological classification | Janus kinase (JAK) inhibitor |
Pharmacological action | Inhibits Janus kinase (JAK) enzymes, reduces inflammation, treats rheumatoid arthritis, severe alopecia areata, and COVID-19 |
Storage conditions | Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F). |
Olumiant: What is it?
Prescription pharmaceutical Olumiant (baricitinib) falls under the Janus kinase (JAK) inhibitor class of medications. It acts by inhibiting some immune system enzymes linked to inflammation. Adults with moderate to severe rheumatoid arthritis (RA), an inflammatory illness that causes joint inflammation, are treated with Olumiant. It can also be used to treat people suffering from severe alopecia areata, a disorder causing hair loss.
Composition of Olumiant
The active constituent in olumiant pills is baricitinib. Included among the inactive components in the tablets are lactose mon carbohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, and iron oxide red.
Benefits and Effects of Olumiant
Olumiant has been demonstrated to be useful in lowering rheumatoid arthritis symptoms, including pain, edema, and joint stiffness. It can also help stop joint deterioration from advancing. At 36 weeks, some adults with severe alopecia areata receiving Olumiant showed 80% scalp hair coverage in clinical trials. In patients who have had notable hair loss in these regions, Olumiant can also help with eyebrow and eyelash restoration.
What is Olumiant Used For?
Adults suffering from mild to severe rheumatoid arthritis are treated with Olumiant. Adults suffering with severe alopecia areata are also treated using it. Olumiant can be taken by itself or in concert with other drugs, including methotrexate.
How to Use Olumiant
Olumiant should be taken orally, either with or without food, at a suggested dose of 4 mg once daily. Individual elements, including age and medical history, could affect the dosage.
Olumiant Dosage and Administration
Olumiant is advised to be taken 4 mg once daily. Individual factors, such as age and medical history, could affect the dosage. Patients with almost whole or complete scalp hair loss—with or without significant eyelash or eyebrow hair loss—should take 4 mg once a day. Patients may have their dosage lowered to 2 mg once daily once they respond enough to treatment at 4 mg once daily.
Side Effects of Olumiant
Olumiant has side effects, just as every drug does. Among the often occurring adverse effects are headaches, nausea, diarrhea, and upper respiratory tract infections. More major adverse effects could potentially develop, including lymphoma, other malignancies, and infections. Before starting Olumiant, be sure your doctor discusses any possible side effects with you.
Olumiant Contraindications
Patients allergic to baricitinib or any of the other components in the drug should not use Olumiant. Pregnant or nursing women should not use it either since it might damage the fetus or infant. Patients suffering from active tuberculosis or severe liver disease should not use Olumiant.
Olumiant Storage Conditions
Olumiant should be kept room temperature, between 20°C and 25°C (68°F and 77°F.). Guard against both light and moisture. Keep Olumiant out of kids reach.
More Details
Before starting Olumiant, be sure your doctor knows your medical history. This covers any other drugs you take, any allergies you have, and any medical conditions you could have. Please speak with your pharmacist or doctor if you have any questions regarding Olumiant.
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