Tobradex, eye drops, 5ml

Composition

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1 ml of eye drops contains:  

Active ingredients:  

tobramycin 3 mg,

dexamethasone 1 mg;

Auxiliary substances:

benzalkonium chloride,

disodium edetate,

sodium chloride,

anhydrous sodium sulfate,

tyloxapol,

hydroxyethylcellulose,

sulfuric acid and / or sodium hydroxide (up to pH),

purified water

Pharmacological action

Tobradex is a combination drug.

Tobramycin is an antibiotic of the aminoglycoside produced by Streptococcus tenebrarius, has a wide spectrum antibacterial action, active against gram-positive and gram-negative microorganisms: staphylococci (including Staphylococcus aureus, Staphylococcus epidermidis), including strains resistant to penicillin; streptococci, including some beta-hemolytic species of the group And, negeroicheskie species, and some Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most species Proteus vulgaris, Haemophilus influenzae, Haemophilus aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus, certain species of Neisseria.

Dexamethasone — corticosteroids. It has anti-inflammatory, anti-allergic and desensitizing effects. It has an anti-exudative effect. Dexamethasone actively suppresses inflammatory processes.

The combination of corticosteroids with an antibiotic (tobramycin) reduces the risk of infection.

Pharmacokinetics

When applied topically, systemic absorption is low.

Indications

• Prevention of postoperative infections;
• blepharitis;
• conjunctivitis;
• keratitis (without damage to the epithelium).

Use during pregnancy and lactation

There is no sufficient experience with the use of Tobradex during pregnancy and lactation.

It can be used for the treatment of pregnant women as prescribed by the attending physician, if the expected therapeutic effect exceeds the risk of possible side effects.

You should stop using the drug for the period of breast-feeding.

Contraindications

• Individual hypersensitivity to Tobradex components;
• corneal and conjunctival viral diseases (including keratitis caused by Negres simplex, chickenpox);
• mycobacterial eye infection;
• fungal eye diseases;
• condition after corneal foreign body removal.

Side effects

Hypersensitivity and allergic reactions (itching, swelling of the eyelids, conjunctival hyperemia).

Side effects caused by the steroid component: increased intraocular pressure; posterior subcapsular cataract, slowing of the wound healing process.

Secondary infection. The development of secondary infection is observed after the use of combined drugs containing corticosteroids in combination with antibiotics.

Fungal infections on the cornea tend to occur especially frequently with prolonged steroid use.

The appearance of non-healing ulcers on the cornea after prolonged treatment with steroid drugs may indicate the development of fungal invasion. Secondary bacterial infection can occur as a result of suppressing the protective reaction of the patient’s body.

Interaction

In the case of use with other topical ophthalmic medications, the interval between their use should be at least 5 minutes.

If tobramycin is administered topically simultaneously with systemic aminoglycoside antibiotics, the overall blood picture should be monitored.

How to take, course of use and dosage

Into the conjunctival sac.

Tobradex eye drops: 1-2 drops every 4-6 hours. In the first 24-48 hours, the dose can be increased to 1-2 drops every 2 hours.

Overdose

Symptoms: irritation of the eye mucosa, itching, lacrimation, swelling of the eyelids, conjunctival hyperemia.

Treatment: washing the eyes with warm water, treatment is symptomatic.

Special instructions

The bottle must be closed after each use.

Do not touch the tip of the pipette to the eye.

Shake the dropper bottle “DropTayner” with eye drops before use, store in an upright position.

Form of production

Eye drops

Storage conditions

At a temperature of 8-27 °C

Shelf life

2 years

Active ingredient

Dexamethasone, Tobramycin

Conditions of release from pharmacies

By prescription

Dosage form

eye drops

Description

Children over 12 years of age, Children as prescribed by a doctor, Adults as prescribed by a doctor

Indications

Conjunctivitis, Eye Infections, Iridocyclitis, Barley on the eye, Blepharitis, Inflammatory eye diseases