Wormin (Mebendazole) tablets 100mg, N24

aWormin is an anthelmintic agent effective to treat enterobiasis and thichocephalosis.

Wormin depletes resources of glycogen in a helminthes body by destroying the glucose utilization process in it. The active ingredient of Wormin – mebendazole, reduces the speed of synthesizing of adenosine triphosphate by impeding tubulin synthesis in cells.

Alimentary canal absorbs insignificant amount of the medication and removes 90% of active ingredient with fecal and 10% with urine.

Uses:

Enterobiasis, ascariasis, ankylostomiasis, strongyloidiasis, trichocephalosis, trichinosis, taeniasis, echinococcosis, alveococcosis, capillaries, gnathostomosis, mixed helminthiasis.

Directions:

• For strongyloidiasis, ankylostomiasis, ascariasis, taeniasis, trichocephalosis and mixed helminthiasis: take 100mg of mebendazole 2 times a day during 3 days.
• For enterobiasis: one time dosage orally of 100 mg (mebendazole). If there is a high risk of recurrence, the course of treatment should be repeated in 2-4 weeks. Children of 2-10 years old should take 25-50 mg.
• For trichinosis: take 200-400mg 3 times a day during the first 3 days, then take 400-500mg 3 times a day the next 7 days.
• For echinococcosis: take 500mg 2 tiames a day during the first 3 days, then take 1500mg (3 intakes) for the next 3 days; then take 25-30mg per 1 kg of body weight per day(3-4 intakes)

Warnings:

a

• Marked hepatic disorder
• Pregnancy
• Breast-feeding
• Children 2 years of age and under
• Hyper sensitive to mebendazole

Side effects:

• Digestive system: rarely nausea, abdomen pain. If taken in large dosage for extended time – vomit, diarrhea, transitional increase of hepatic transaminase activity
• Central nervous system: rarely – dizziness. If taken in large dosage for extended time –headache
• Blood formation: if taken in large dosage for extended time – leukopenia, anemia, eosinophilia
• Urinary system: if taken in large dosage for extended time – hematuria, cylindruria
• Other: if taken in large dosage for extended time – allergic reactions, shedding

Inreaction with other medications:

Mebendazole decreases the need in insulin in patients with diabetes.

It is recommended to avoid taking mebendazole with lipophilic substances. When taking simultaneously, cimetidine may increase and carbamazepine and other metabolism inductors may decrease mebendazole concentration in blood.

Wormin is an anthelmintic medication that helps to destroy parasites such as helminthes.