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Tevagrastim: What It Is and How It Works

Tevagrastim is a medication containing the active ingredient filgrastim. Filgrastim is a protein that stimulates the bone marrow to produce more white blood cells. White blood cells are crucial components of the immune system, helping your body fight off infections.

Uses of Tevagrastim

Tevagrastim is used to treat various conditions, including:

• Cancer treatment (to help reduce the risk of infections following chemotherapy)
• Bone marrow transplantation (to help reduce the risk of infections after transplantation)
• Severe persistent neutropenia (a long-term condition where the body doesnt produce enough white blood cells)
• Collection of stem cells (to increase the number of stem cells in the bone marrow for transplantation)
• Advanced HIV infection (to help reduce the risk of other infections in people with advanced HIV)

Tevagrastim Composition

Tevagrastim is available in pre-filled syringes containing either 0.5 ml or 0.8 ml of solution. Each milliliter of solution contains 60 million international units (MIU) of filgrastim (600 µg). Therefore:

• Each 0.5 ml syringe contains 30 MIU (300 µg) of filgrastim.
• Each 0.8 ml syringe contains 48 MIU (480 µg) of filgrastim.

Benefits of Tevagrastim

Tevagrastim offers several benefits, including:

• Reduces the risk of infections following chemotherapy or bone marrow transplantation.
• Helps the body fight infections in cases of severe persistent neutropenia.
• Assists in collecting stem cells for transplantation.

How to Use Tevagrastim

Tevagrastim is typically administered as a daily subcutaneous injection (under the skin). It can also be given as a slow intravenous injection into a vein. The dosage will vary depending on your condition and weight. Your doctor will determine the appropriate dosage for you.

Side Effects of Tevagrastim

Like any medication, Tevagrastim can cause side effects. While not everyone experiences them, common side effects include:

• Bone pain
• Muscle pain
• Headache
• Fatigue
• Nausea
• Diarrhea

Rare but serious side effects can also occur, including:

• Allergic reactions
• Lung problems
• Blood clots
• Spleen problems
• Leukemia (blood cancer)

If you experience any side effects, consult your doctor.

Contraindications of Tevagrastim

Tevagrastim is not suitable for everyone. It should be avoided if you:

• Are allergic to filgrastim or any other component of Tevagrastim.
• Have sickle cell anemia.
• Have leukemia.

Its crucial to consult your doctor to ensure Tevagrastim is appropriate for you.

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