Composition
One Wormin tablet:
- 0.1 g of mebendazole.
Auxiliary components:
- Calcium hydrophosphate;
- Magnesium stearate;
- Sodium Lauryl Sulfate;
- Sunset orange food coloring;
- Starch;
- Gelatin;
- Talcum powder.
- Sunset yellow food coloring;
- Vanillin.
Pharmacological action
Broad-spectrum anthelmintic; most effective for enterobiosis.
Causes irreversible disruption of glucose utilization in the helminth’s body and inhibits ATP synthesis.
Indications
Enterobiosis, ascariasis, hookworm disease, strongyloidosis, trichocephalosis, trichinosis, teniosis, echinococcosis, alveococcosis, capillariosis, gnathostomosis, mixed helminthiasis.
Contraindications
Severe liver function disorders, pregnancy, lactation (breastfeeding), children under 2 years of age, hypersensitivity to mebendazole.
Side effects
From the digestive system: Â rarely – nausea, abdominal pain; when used in high doses for a long time, vomiting, diarrhea, and a transient increase in the activity of hepatic transaminases in the blood serum are possible.
From the central nervous system: Â rarely – dizziness; when used in high doses for a long time-headache.
From the hematopoietic system: Â when used in high doses for a long time, leukopenia, anemia, and eosinophilia are possible.
From the urinary system: Â when used in high doses for a long time – hematuria, cylindruria.
Other services: Â when used in high doses for a long time – allergic reactions, hair loss.
Interaction
Mebendazole reduces the need for insulin in diabetic patients.
Co-use of mebendazole with lipophilic substances should be avoided.
When used concomitantly, cimetidine may increase, and carbamazepine and other metabolic inducers may decrease, the concentration of mebendazole in the blood.
How to take, course of use and dosage
Adults and children over 10 years of age with enterobiosis – at a dose of 100 mg once.
Children aged 2 to 10 years – at a dose of 25-50 mg once.
In case of a high probability of re-invasion, the reception is repeated in 2-4 weeks at the same dose.
Simultaneous treatment of all family members is recommended.
For ascariasis, trichocephalosis, hookworm disease, teniosis, strongyloidosis and mixed helminthiasis – 100 mg in the morning and evening for 3 days.
With trichinosis – 200-400 mg 3 times/day for 3 days, and from the 4th to the 10th day-400-500 mg 3 times/day.
With echinococcosis-500 mg 2 times/day for the first 3 days, then in the same dose 3 times / day for the next 3 days.
In the future, it is used in a dose of 25-30 mg / kg / day in 3-4 doses.
Special instructions
With prolonged use, it is necessary to monitor the picture of peripheral blood, liver and kidney function.
During the day after taking mebendazole, do not allow alcohol consumption.
Do not use a laxative after taking mebendazole.
Periodic examination of anal and fecal smears is mandatory after the end of treatment (therapy is considered effective in the absence of helminths or their eggs for the next 7 days).
Form of production
Pills.
Active ingredient
Mebendazole
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
Children as prescribed by a doctor, Children over 3 years of age, Adults as prescribed by a doctor
Indications
Worms
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Side effects of Wormin, pills 100mg 24pcs.
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