Tergynan, Vaginal tablets, 6pcs

Composition

Active ingredients:

ternidazole-0.2 g,

neomycin sulfate-0.1 g or 65,000 IU,

nystatin-100,000 IU,

prednisone sodium metasulfobenzoate-0.0047 g,

equivalent to prednisone – 0.003 g.

Auxiliary substances:

wheat starch-0.264 g,

lactose monohydrate-q. s. up to 1.2 g,

colloidal silicon dioxide-0.006 g,

magnesium stearate-0.01 g,

sodium carboxymethyl starch-0.048 g

Pharmacological action

Combined drug for topical use in gynecology. It has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effects; ensures the integrity of the vaginal mucosa and constant pH.

Ternidazole is an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (a component of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect, is also active against anaerobic bacteria, in particular Gardnerella.

Neomycin is a broad-spectrum antibiotic from the group of aminoglycosides. Acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and Gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp. ) microorganisms; against Streptococcus spp., inactive.

Microbial resistance develops slowly and to a small extent.

Nystatin is an antifungal antibiotic from the polyene group, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisone is a dehydrated analogue of hydrocortisone, which has a pronounced anti-inflammatory, anti-allergic, and anti-exudative effect.

Indications

Treatment of vaginitis caused by microorganisms sensitive to the drug, including:

• bacterial vaginitis;
• trichomoniasis of the vagina;
• vaginitis caused by fungi of the genus Candida;
• mixed vaginitis.

Prevention of vaginitis, including:

• before gynecological operations;
• before childbirth and abortion;
• before and after the installation of intrauterine devices;
• before and after diathermocoagulation of the cervix;
• before hysterography.

Use during pregnancy and lactation

It is possible to use Terzhinan during pregnancy and lactation (breastfeeding )according to indications.

Contraindications

Hypersensitivity to the components of the drug.

Side effects

Burning sensation, itching and irritation in the vagina (especially at the beginning of treatment).

In some cases, allergic reactions are possible.

How to take, course of use and dosage

For vaginal use.

One tablet is inserted deep into the vagina in the “lying” position before going to bed.

Before being inserted into the vagina, the tablet should be kept in water for 20-30 seconds.

After the introduction, you need to lie down for 10-15 minutes.

The average duration of the therapeutic course of therapy is 10 days; in the case of confirmed mycosis, it can be extended to 20 days; the average duration of the preventive course is 6 days.

Overdose

Due to the low degree of absorption into the systemic circulation, overdose is unlikely.

Special instructions

It is necessary to carry out simultaneous treatment of the sexual partner because of the risk of re-infection.

Form of production

Vaginal tablets

Storage conditions

Store at room temperature.

See expiration date. on the packaging.

Active ingredient

Ternidazole, Neomycin sulfate, Nystatin, Prednisone sodium metasulfobenzoate

Conditions of release from pharmacies

By prescription

Dosage form

vaginal tablets

Description

Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor, Adults as prescribed by a doctor

Indications

Inflammation of the female genital organs, Vaginitis