Adonis-brom (Tablets) Instructions for Use

Marketing Authorization Holder

Vifitech, CJSC (Russia)

ATC Code

C01AX (Other cardiac glycosides)

Dosage Form

Adonis-brom

Coated tablets: 20 pcs.

Dosage Form, Packaging, and Composition

Coated tablets yellow in color, round, biconvex.

10 pcs. – contour cell packaging (2) – cardboard packs.
25 pcs. – orange glass jars (1) – cardboard packs.

Clinical-Pharmacological Group

Sedative herbal preparation

Pharmacotherapeutic Group

Drugs for the treatment of heart diseases; cardiac glycosides; other cardiac glycosides

Pharmacological Action

It has a sedative, as well as a moderate cardiotonic effect.

Pharmacokinetics

No data available.

Indications

• Neurotic syndrome, incl. accompanied by tachycardia.

ICD codes

Dosage Regimen

Administer the tablets orally.

Take one tablet three times daily.

Always take the dose after meals to improve tolerability.

The standard course of treatment is 25 to 30 days.

Do not initiate a repeated course without consulting a physician; the advisability of further treatment must be determined by a doctor based on clinical assessment.

Monitor for potential adverse effects, particularly with prolonged use.

Adhere strictly to the prescribed dosage and duration to minimize the risk of bromide accumulation.

Adverse Reactions

Possible allergic reactions, nausea, vomiting; with long-term use – cough, runny nose, apathy, general weakness, impaired perception, memory loss, skin rash, conjunctivitis.

Contraindications

• Severe bradycardia;
• AV block of varying degrees;
• Morgagni-Adams-Stokes syndrome;
• Angina pectoris;
• Erosions;
• Ulcers of the esophagus, stomach and duodenum;
• Sucrase/isomaltase deficiency;
• Fructose intolerance;
• Glucose-galactose malabsorption;
• Pregnancy;
• Lactation;
• The drug is not recommended for use in children under 18 years of age due to lack of data on efficacy and safety;
• Hypersensitivity to the components of the drug.

Use in Pregnancy and Lactation

It is not recommended for use during pregnancy and lactation due to the lack of specific data on safety of use in this category of patients.

Pediatric Use

The drug is not recommended for use in children under 18 years of age due to lack of data on efficacy and safety.

Special Precautions

Patients with diabetes should take into account that 1 tablet of the drug contains about 0.263 g of carbohydrates (0.022 XE).

Effect on ability to drive vehicles and operate machinery

With long-term use of the drug in large doses, a decrease in the speed of psychomotor reactions is possible, which should be taken into account when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Overdose

Symptoms of bromide overdose cough, runny nose, apathy, headache, general weakness, impaired perception, memory loss, skin rash, conjunctivitis.

Treatment it is necessary to discontinue the drug, administer large amounts (in the absence of contraindications) of sodium chloride – 10-20 g/day (accelerates the excretion of bromine) in combination with plenty of fluids (3-5 l/day).

Symptoms of cardiac glycoside overdose severe bradycardia, polytopic extrasystole, bigeminy or trigeminy, slowing of atrioventricular conduction; in severe cases – ventricular flutter and cardiac arrest.

Treatment a break in their use, if necessary, potassium preparations and antiarrhythmic agents are prescribed.

Drug Interactions

The drug enhances the effect of hypnotics and other drugs that depress the CNS, which requires dose adjustment when used concomitantly.

Storage Conditions

Store the drug in a dry, light-protected place at a temperature not exceeding 25°C (77°F). Keep out of reach of children.

Shelf Life

Shelf life – 2 years.

Do not use after the expiration date.

Dispensing Status

The drug is approved for use as an over-the-counter product.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.