Allii sativi tinctura (Tincture) Instructions for Use

Marketing Authorization Holder

Moscow Pharmaceutical Factory CJS (Russia)

ATC Code

V03A (Other therapeutic agents)

Active Substance

Garlic (BP British Pharmacopoeia)

Dosage Form

Allii sativi tinctura

Tincture 200 g/1 L: bottle 25 ml, 50 ml, 90 ml, or 100 ml

Dosage Form, Packaging, and Composition

25 ml – dark glass dropper bottle (1) – cardboard packs.
50 ml – dark glass bottles (1) – cardboard packs.
90 ml – dark glass bottles (1) – cardboard packs.
100 ml – dark glass bottles (1) – cardboard packs.

Clinical-Pharmacological Group

Hypolipidemic herbal preparation

Pharmacotherapeutic Group

Antimicrobial agent of plant origin

Pharmacological Action

Herbal remedy. It exerts bactericidal, antiviral, and fungicidal effects, associated with phytoncides and the glycoside allicin. Garlic is effective against pathogens of intestinal infections (dysentery, typhoid, pathogenic enterococci, Escherichia coli with altered enzymatic properties), staphylococci, alpha-hemolytic streptococci.

The glycoside alliin is converted by the enzyme alliinase into allicin, which possesses antimicrobial activity. Garlic is eubiotic; thanks to vitamins C, B, D, PP, it contributes to the normalization of the functions of the automicroflora.

It improves digestion processes, enhances the formation and secretion of bile, contributes to the reduction of cholesterol and glucose levels in the blood, has a beneficial effect on metabolism, especially in patients with diabetes mellitus and obesity.

Due to organic acids, vitamins, macro- and microelements (especially magnesium, potassium, selenium, zinc, manganese), it stimulates hematopoiesis, exhibits antihypoxic and angioprotective effects. Cardiotonic action in combination with the expansion of peripheral vessels and hypolipidemic action contributes to the normalization of the functions of the cardiovascular system, especially in elderly patients. Anthelmintic effect is manifested in ascariasis and enterobiasis.

When applied externally, especially in fresh form, in addition to antimicrobial action, manifestations of antihistaminic, analgesic, antipruritic, keratolytic, and depigmenting action are possible; it stimulates hair growth.

Indications

For oral administration: as part of combination therapy for infectious and inflammatory diseases of the respiratory organs (including rhinitis, tonsillitis, sinusitis, sinusitis, bronchitis, pneumonia); chronic diseases of the gastrointestinal tract, dysbiosis, atonic constipation; neurocirculatory dystonia of the hypertensive type, arterial hypertension, atherosclerosis; ascariasis, enterobiasis.

For external use: as part of combination therapy for dermatitis, pyoderma, purulent wounds.

ICD codes

Dosage Regimen

Administer orally or externally. Determine the regimen individually based on indication, clinical presentation, and patient age.

For oral administration, dilute 10-15 drops of the tincture in a small volume of water. Take the prepared solution 2-3 times daily, 30 minutes before meals. The typical treatment course is 2-4 weeks.

For external use, apply the tincture topically to affected skin areas. Use as a lotion or for wound irrigation 1-2 times per day. Avoid application on extensive areas of damaged skin or mucous membranes.

For helminthic infestations (ascariasis, enterobiasis), administer a single dose of 15-20 drops diluted in water or milk. Repeat the dose if necessary, as directed by a physician.

For respiratory tract infections, use the standard oral regimen. Inhaling the vapors from the tincture is also permissible for symptomatic relief.

Strictly adhere to the recommended dosage and frequency of administration. Do not exceed the prescribed dose. The maximum single dose is 20 drops. The maximum daily dose is 60 drops.

For pediatric patients, use only age-appropriate garlic preparations and dosages. Consult a pediatrician for the correct regimen for a child.

In elderly patients and those with cardiovascular comorbidities, initiate therapy with lower doses. Monitor for adverse effects such as tachycardia or heart pain.

Discontinue use and consult a physician if severe dyspepsia, signs of renal irritation, or significant skin reactions occur.

Adverse Reactions

Possible: allergic reactions; with oral administration – dyspepsia, irritation of the renal parenchyma, when used in high doses causes tachycardia, heart pain; when applied to the skin – hyperemia, burning, rash.

Contraindications

Hypersensitivity to garlic; for oral administration – acute and chronic kidney diseases, hypothyroidism, biliary dyskinesia of the hyperkinetic type, hepatitis, cholelithiasis, gastritis and peptic ulcer of the stomach and duodenum in the acute phase; pregnancy, breastfeeding period.

Use in Pregnancy and Lactation

Contraindicated for oral administration during pregnancy and breastfeeding.

Use in Hepatic Impairment

Contraindicated for oral administration in hepatitis, cholelithiasis, biliary dyskinesia of the hyperkinetic type.

Use in Renal Impairment

Contraindicated for oral administration in acute and chronic kidney diseases.

Pediatric Use

Appropriate dosage forms of garlic preparations should be used in children.

Geriatric Use

Should be prescribed with caution in elderly patients to avoid worsening of concomitant diseases.

Special Precautions

During the use of garlic preparations, a change in the smell of the skin and exhaled air is possible.

Storage Conditions

Store at 8°C (46°F) to 15°C (59°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.