AngioNorm^® (Tablets) Instructions for Use

Marketing Authorization Holder

Otisipharm, JSC (Russia)

Manufactured By

PharmVILAR NPO, LLC (Russia)

ATC Code

C05C (Drugs reducing capillary permeability)

Dosage Form

AngioNorm^®

Coated tablets: 30, 70, or 100 pcs.

Dosage Form, Packaging, and Composition

Coated tablets yellow in color, round, biconvex; on the cross-section: a yellow and white coating and a core ranging from light brown to dark brown in color, light inclusions are allowed.

	1 tab.
Dry extract of AngioNorm^® (obtained from a mixture of medicinal plant materials – hawthorn fruits, licorice roots, horse chestnut seeds, rose hips with a content of the sum of flavonoids calculated as avicularin 0.50 mg)	100 mg

Excipients : lactose monohydrate – 57.00 mg, potato starch – 89.00 mg, microcrystalline cellulose – 1.00 mg, stearic acid – 3.0 mg.

Coating composition, obtained by the build-up method sucrose – 141.10 mg, magnesium hydroxycarbonate – 27.64 mg, colloidal silicon dioxide – 2.20 mg, titanium dioxide – 2.70 mg, low molecular weight povidone – 2.20 mg, talc – 1.90 mg, tropaeolin-O dye – 0.06 mg.
Glazing mastic composition beeswax – 0.10 mg, liquid paraffin – 0.10 mg.

10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (7) – cardboard packs.
10 pcs. – contour cell packs (10) – cardboard packs.
30 pcs. – polymer jars (1) – cardboard packs.

Clinical-Pharmacological Group

Angioprotector

Pharmacotherapeutic Group

Angioprotective agent

Pharmacological Action

AngioNorm^® has pronounced antiplatelet, antithrombotic activity, angioprotective and anti-inflammatory properties, exerts a venotonic and microcirculation-improving effect, and activates the diuretic function of the kidneys.

AngioNorm^® affects the general condition of the body: it increases physical performance, exhibits stress-protective activity and a moderate analgesic effect.

Indications

As part of complex therapy for diseases accompanied by vascular disorders, such as increased platelet aggregation (thromboses, thromboembolisms); impaired capillary permeability and microcirculation (capillary thromboses); impaired venous circulation (varicose veins, post-thrombotic syndrome, thrombophlebitis).

ICD codes

Open the list of ICD codes

ICD-10 code	Indication
I74	Embolism and thrombosis of arteries
I78.8	Other diseases of capillaries
I80	Phlebitis and thrombophlebitis
I82	Embolism and thrombosis of other veins
I83	Varicose veins of lower extremities
I87.0	Postthrombotic syndrome

ICD-11 code	Indication
BB01.0	Pulmonary arterial hypertension
BD5Z	Diseases of arteries or arterioles, unspecified
BD70.0	Superficial thrombophlebitis of lower extremities
BD70.2	Migratory thrombophlebitis
BD70.Z	Superficial thrombophlebitis, unspecified
BD71.4	Deep vein thrombosis of lower extremity
BD74.1Z	Varicose veins of lower extremities, unspecified
BD74.Z	Chronic venous insufficiency of lower extremities, unspecified
BD7Z	Diseases of veins, unspecified
DB98.5	Budd-Chiari syndrome
EF20.Z	Acquired anomalies of the skin's blood vessels, unspecified
BD72	Venous thromboembolism
XA60H0	Vena cava

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Administer AngioNorm^® orally, ensuring intake occurs 40 minutes after meals to optimize absorption and tolerance.

The standard therapeutic dose is 1 tablet taken three times daily.

In cases of good patient tolerance, the dose may be increased to a maximum of 2 tablets three times daily.

Adhere to a treatment course duration of up to 3 weeks.

Do not extend therapy beyond this period without medical reevaluation.

The decision to initiate a repeated treatment course must be determined by a physician based on clinical assessment.

Monitor for therapeutic effect and potential adverse reactions throughout the treatment period.

Adverse Reactions

Allergic reactions, dyspeptic disorders.

Contraindications

Hypersensitivity to the drug components;
Severe chronic diseases of the liver, kidneys, and gastrointestinal tract with impaired function;
Lactase deficiency, lactose intolerance, sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption (due to the presence of lactose and sucrose).

It is not recommended to prescribe the drug to children under 18 years of age due to the lack of data on the safety of clinical use.

Use in Pregnancy and Lactation

It is not recommended to prescribe the drug during pregnancy and breastfeeding due to the lack of data on the safety of clinical use.

Use in Hepatic Impairment

Contraindicated in severe chronic liver diseases with impaired function.

Use in Renal Impairment

Contraindicated in severe chronic kidney diseases with impaired function.

Pediatric Use

Contraindicated for use under 18 years of age.

Special Precautions

The use of the drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Information for patients with diabetes mellitus: 1 tablet contains 0.023 bread units (BU), in the maximum daily dose – 0.138 bread units (BU).

Overdose

With prolonged use of AngioNorm^® in doses exceeding the recommended daily dose, an increase in the severity of side effects is possible. Treatment is symptomatic.

Drug Interactions

The use of AngioNorm^® can be combined with other drugs: lipid-lowering, anti-inflammatory, analgesic agents, antibiotics, direct and indirect anticoagulants.

Storage Conditions

The drug should be stored out of the reach of children, in a dry, light-protected place at a temperature not exceeding 25°C (77°F).

Shelf Life

Shelf life – 5 years. Do not use after the expiration date printed on the packaging.

Dispensing Status

The drug is available without a prescription.

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer