Artra^® MSM (Tablets) Instructions for Use

Marketing Authorization Holder

Takeda Pharmaceuticals, LLC (Russia)

Manufactured By

Eagle Nutritionals Inc. (USA)

For

TAKEDA PHARMACEUTICALS INTERNATIONAL, AG (Switzerland)

Labeled By

UNIPHARM, Inc. (USA)

Dosage Form

Artra® MSM

Film-coated tablets: 30, 60, 90, 100, or 120 pcs.

Dosage Form, Packaging, and Product Composition

Film-coated tablets, with a mass of 1690 mg.

* % of the Adequate Intake Level (AIL) according to the Unified Requirements of the Customs Union of EurAsEC;
** does not exceed the upper permissible intake level.

Composition glucosamine hydrochloride, Chondroitin sulfate sodium, methylsulfonylmethane, carrier microcrystalline cellulose, carrier croscarmellose, stabilizer dicalcium phosphate, purified water, stabilizer stearic acid, carrier hydroxypropyl methylcellulose, sodium hyaluronate, stabilizer polydextrose, stabilizer magnesium stearate, colorant titanium dioxide, anticaking agent silicon dioxide, anticaking agent talc, maltodextrin, colorants iron oxides and hydroxides, medium-chain triglycerides.

30 pcs. – polyethylene bottles (1) – cardboard boxes.
60 pcs. – polyethylene bottles (1) – cardboard boxes.
90 pcs. – polyethylene bottles (1) – cardboard boxes.
100 pcs. – polyethylene bottles (1) – cardboard boxes.
120 pcs. – polyethylene bottles (1) – cardboard boxes.

Therapeutic Category

Dietary supplement – source of glucosamine, chondroitin, and hyaluronic acid

Properties

Artra^® MSM is a dietary supplement.

It contains high concentrations of glucosamine, chondroitin, hyaluronic acid, and methylsulfonylmethane (MSM), which in combination exhibit synergy, complementing and enhancing each other’s effects.

With age, the synthesis of glucosamine and chondroitin decreases, and methylsulfonylmethane (a natural source of sulfur) enters the body in negligible amounts.

Chondroitin and Glucosamine play a crucial role in the restoration of connective tissue, improve the shock-absorbing properties of cartilage, and increase joint mobility.

The components of Artra^® MSM

• Help reduce inflammation and pain in the joints;
• Help increase joint mobility;
• Help accelerate the regeneration of cartilage tissue;
• Help protect articular cartilage;
• Are a source for the formation of cartilage matrix and connective tissue, contributing to their restoration.

Glucosamine and Chondroitin sulfate are involved in the synthesis of connective tissue.

Glucosamine is a structural component for the formation (synthesis) of other components of cartilage structures, inhibits the development of degenerative processes in the joints, and restores their function.

The introduction of exogenous glucosamine enhances the production of cartilage matrix.

Chondroitin sulfate sodium serves as an additional substrate for the formation of a healthy cartilage matrix, is part of the synovial (joint) fluid, which ensures the sliding of articular surfaces and also provides nutrition to the cartilage; helps reduce the need for NSAIDs.

Hyaluronic acid is part of the synovial fluid, where it acts as a lubricant, reducing friction between articular surfaces; it is part of the cartilage, where it performs a “shock-absorbing” function (maintains the stability of cartilage tissue under compression); it is an important component of synovial fluid, determining its viscoelastic properties; it forms a covering layer over the entire inner surface, which protects the articular cartilages and synovial membrane from mechanical damage, as well as from free radicals and inflammatory factors.

On the surface of mucous membranes, Hyaluronic acid forms a thin semi-permeable protective layer, covering nerve endings and preventing irritation; it stimulates the formation of collagen.

Methylsulfonylmethane is a source of biologically available sulfur for the body – a component of proteins that make up all connective tissues.

MSM reduces the risk of inflammatory processes, accelerates the synthesis of collagen proteins, and helps maintain joints in a healthy state.

Scope of Application

Of the Artra^® MSM product

As a dietary supplement:

• To reduce inflammation and pain in the joints;
• To increase joint mobility.

ICD codes

Dosage Regimen

Adults – 2 tablets once a day with meals.

The duration of intake is 2 months.

Contraindications

• Individual intolerance to product components;
• Renal failure;
• Pregnancy;
• Breastfeeding.

Use during pregnancy and lactation

Contraindicated for use during pregnancy and breastfeeding.

Special instructions

Consult a physician before use.

Storage Conditions

The product should be stored out of reach of children at a temperature between 15°C (59°F) and 25°C (77°F) and relative air humidity not exceeding 60%.

Shelf Life

Shelf life – 2 years.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.