CFD/SAGM (Solvent) Instructions for Use

Marketing Authorization Holder

Green Cross Medical Science Corporation (Republic of Korea)

ATC Code

V07AC (Auxiliary agents for blood transfusion)

Dosage Form

CFD/SAGM

Hemopreservative solution: containers

Dosage Form, Packaging, and Composition

Hemopreservative solution (CFD) is transparent, slightly yellowish or colorless.

Excipients : water for injections – up to 100 ml.

Hemopreservative solution (SAGM) is transparent, slightly yellowish or colorless.

Excipients : water for injections – up to 100 ml.

63 ml – containers (3) – aluminum bags (10) – cardboard boxes.
63 ml – containers (4) – aluminum bags (10) – cardboard boxes.
100 ml – containers (3) – aluminum bags (10) – cardboard boxes.
100 ml – containers (4) – aluminum bags (10) – cardboard boxes.

Clinical-Pharmacological Group

Donor blood preservative preparation

Pharmacotherapeutic Group

Hemopreservative-auxiliary substance

Pharmacological Action

Hemopreservative. It prevents the process of blood clotting and provides the necessary nutrients to support metabolism and stabilize blood cells during storage.

It ensures the preservation of red blood cells for 42 days by increasing the functional activity and viability of red blood cells.

Adenine is used by red blood cells for ATP synthesis, as a result, their viability increases.

Indications

• Preservation of blood and red blood cell mass.

ICD codes

Dosage Regimen

Perform blood collection and the preparation of its components strictly in accordance with the official “Instructions for the Collection and Preservation of Blood” approved by the Ministry of Health of the Russian Federation.

Administer blood components exclusively according to the “Instructions for the Use of Blood Components” approved by the Ministry of Health of the Russian Federation.

Maintain a precise ratio of the hemopreservative solution to blood of 14 ml per 100 ml of whole blood to ensure proper anticoagulation and preservation efficacy.

Adverse Reactions

Monitor for allergic reactions, which are possible following exposure to the solution’s components.

These reactions may manifest as urticaria, pruritus, or more severe hypersensitivity responses; manage any such events with appropriate medical intervention immediately.

Contraindications

• Hypersensitivity to any of the components of the combination.

Special Precautions

The same system should not be used for transfusions of blood, red blood cell mass, and intravenous infusion of other medicines.

Drug Interactions

Do not mix with other medicinal products as the solution is physically and chemically incompatible.

Avoid concurrent administration through the same intravenous line to prevent potential precipitation or inactivation of either the hemopreservative or the co-administered drug.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Rx Only

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.