Chlorhexidine bigluconate (Solution, Spray, Suppositories) Instructions for Use
ATC Code
D08AC02 (Chlorhexidine)
Active Substance
Chlorhexidine (Rec.INN registered by WHO)
Clinical-Pharmacological Group
Antiseptic for external and topical use
Pharmacotherapeutic Group
Antiseptics and disinfectants; biguanides and amidines
Pharmacological Action
Antiseptic agent. Chlorhexidine exhibits bactericidal action (against gram-positive and gram-negative bacteria) at a temperature of 22°C (71.6°F) and exposure for 1 minute; fungicidal action at a temperature of 22°C (71.6°F) and exposure for 10 minutes; virucidal action (against lipophilic viruses).
It acts on bacterial spores only at elevated temperatures. It is stable; after skin treatment, it remains on it in a certain amount sufficient to manifest a bactericidal effect. It retains activity (although somewhat reduced) in the presence of blood, pus, various secretions, and organic substances.
It does not have a damaging effect on items made of glass, plastic, and metals.
Pharmacokinetics
When applied topically and externally, it is not absorbed into the systemic circulation and does not have a systemic effect.
Indications
Trichomonal colpitis, cervical erosion, vulvar itching, prevention of venereal diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis); gingivitis, stomatitis, aphthae, periodontitis, alveolitis, disinfection of removable dentures; angina; postoperative care for patients in ENT and dentistry departments.
Treatment of wounds, burn wounds and surfaces; disinfection of the patient’s skin.
Treatment of the surgeon’s hands, medical personnel, and the surgical field before diagnostic manipulations and surgery.
Disinfection of working surfaces of devices (including thermometers) and equipment for which thermal treatment is undesirable.
ICD codes
| ICD-10 code | Indication |
| A51 | Early syphilis |
| A52 | Late syphilis |
| A54 | Gonococcal infection |
| A56.0 | Chlamydial infections of lower genitourinary tract |
| A56.1 | Chlamydial infections of pelvic organs and other genitourinary organs |
| A59 | Trichomoniasis |
| J03 | Acute tonsillitis |
| J35.0 | Chronic tonsillitis |
| K05 | Gingivitis and periodontal diseases |
| K10.3 | Alveolitis of jaws |
| K12 | Stomatitis and related lesions |
| L29.2 | Pruritus vulvae |
| N76 | Other inflammatory diseases of vagina and vulva |
| N77.1 | Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere |
| N86 | Erosion and ectropion of cervix |
| T14.0 | Superficial injury of unspecified body region (including abrasion, bruise, contusion, hematoma, bite of nonvenomous insect) |
| T14.1 | Open wound of unspecified body region |
| T30 | Burns and corrosions of unspecified body region |
| T79.3 | Posttraumatic wound infection, not elsewhere classified |
| Z29.8 | Other specified prophylactic measures |
| Z51.4 | Preparatory procedures for subsequent treatment or examination, not elsewhere classified |
| Z97.2 | Presence of dental prosthesis |
| ICD-11 code | Indication |
| 1A61.Z | Early syphilis, unspecified |
| 1A62.Z | Late syphilis, unspecified |
| 1A7Z | Gonococcal infection, unspecified |
| 1A81.0 | Chlamydial infection of lower genitourinary tract |
| 1A81.1 | Chlamydial infection of internal reproductive organs |
| 1A92 | Trichomoniasis |
| 1F23.10 | Candidiasis of vulva and vagina |
| 1F65 | Enterobiasis |
| 1H0Z | Unspecified infection |
| CA03.Z | Acute tonsillitis, unspecified |
| CA0F.Y | Other specified chronic diseases of the palatine tonsils and adenoids |
| DA01.Z | Diseases of the oral mucosa, unspecified |
| DA06.1 | Alveolitis of jaw |
| DA0B.Z | Gingival diseases, unspecified |
| DA0C.Z | Periodontal diseases, unspecified |
| DA0Z | Diseases or disorders of the orofacial complex, unspecified |
| EH92 | Dermatoses provoked by friction or mechanical impact |
| EH92.1 | Blister due to friction |
| GA00 | Vulvitis |
| GA02.Z | Unspecified vaginitis |
| GA0Z | Inflammatory diseases of female genital tract, unspecified |
| GA15.1 | Erosion or ectropion of cervix |
| GA42.0 | Pruritus vulvae |
| ND56.0 | Superficial injury of unspecified body region |
| ND56.1 | Open wound of unspecified body region |
| NE11 | Burn of unspecified body region |
| NF0A.3 | Posttraumatic wound infection, not elsewhere classified |
| QB51.A | Presence of dental prosthetic device |
| QB9A | Preparatory procedures for subsequent treatment |
| QC05.Z | Prophylactic measures, unspecified |
| 1A94.0 | Genital or urogenital tract infection caused by Herpes simplex virus |
| GA41 | Ulcerative or erosive diseases of vulva |
Dosage Regimen
| The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen. |
For wound treatment and burn surfaces, apply the solution or spray to the affected area. Use sufficient volume to ensure complete coverage.
For skin disinfection prior to injection, apply the solution to the intended site. Allow it to dry completely before the procedure.
For surgical hand scrubbing, wash and rinse hands. Apply 5 ml of solution and scrub for 3 minutes. Rinse thoroughly under running water.
For preoperative skin preparation, apply the solution generously to the surgical site. Repeat the application using a sterile sponge.
For genitourinary tract infections, insert one vaginal suppository daily, preferably at bedtime. The typical treatment course is 7 to 10 days.
For venereal disease prevention, use the solution for external genital treatment within 2 hours after sexual intercourse. Apply the solution and do not wash it off for at least 5 minutes.
For gingivitis and stomatitis, use a 0.05% to 0.1% solution as a mouth rinse. Rinse for 30 seconds twice daily after brushing.
For disinfection of removable dentures, soak the prosthesis in the solution for 15-20 minutes. Rinse thoroughly with water before reinsertion.
For angina, use a diluted solution for gargling. Gargle 3-4 times daily for 5-7 days.
For equipment disinfection, wipe surfaces or immerse items in the solution. Ensure contact time is at least 1 minute for bactericidal effect.
Avoid contact with eyes, meninges, and the auditory nerve. Do not use with soap or other anionic agents.
Adverse Reactions
Allergic reactions: skin rash, itching, severe allergic reactions, including anaphylaxis.
Skin and subcutaneous tissue disorders: dry skin, itching, dermatitis, photosensitivity.
Local reactions: staining of tooth enamel, tartar deposition, taste disturbance.
Contraindications
Hypersensitivity to chlorhexidine, dermatitis.
With caution
Children, pregnancy, breastfeeding period.
Use in Pregnancy and Lactation
If it is necessary to use during pregnancy and breastfeeding, the expected benefit of therapy for the mother and the possible risk to the fetus should be weighed.
Pediatric Use
Use with caution in children.
Geriatric Use
The drug is approved for use in elderly patients.
Special Precautions
Chlorhexidine must not be allowed to get into the eyes (except for a special dosage form intended for use in ophthalmology), as well as to come into contact with the meninges and the auditory nerve.
Drug Interactions
It is used in a neutral environment; at pH 5-8, the difference in activity is small; at pH above 8, a precipitate forms.
It is not used in combination with anionic compounds, including soap.
It is incompatible with carbonates, chlorides, phosphates, borates, sulfates, and citrates.
The use of hard water reduces bactericidal properties.
It is compatible with medicinal products containing a cationic group (benzalkonium chloride, cetrimonium bromide).
Storage Conditions
Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.
Dispensing Status
Over-the-Counter
Important Safety Information
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.
Medical DisclaimerBrand (or Active Substance), Marketing Authorisation Holder, Dosage Form
Solution for topical and external use 0.05%: fl. 50 ml or 100 ml.
Marketing Authorization Holder
Activa, JSC (Russia)
Manufactured By
Activa, JSC (Russia)
Or
RFK, CJS (Russia)
Dosage Form
 |
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: fl. 50 ml or 100 ml. |
Dosage Form, Packaging, and Composition
Solution for topical and external use 0.05% colorless, transparent or slightly opalescent, odorless.
| 1000 ml | |
| Chlorhexidine bigluconate (20% solution) | 2.5 ml |
Excipients : purified water – up to 1000 ml.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
0.5 l – polyethylene canisters (for hospitals).
1 l – polyethylene canisters (for hospitals).
3 l – polyethylene canisters (for hospitals).
5 l – polyethylene canisters (for hospitals).
Solution for topical and external use 0.05%: 25 ml, 50 ml or 100 ml bottle.
Marketing Authorization Holder
Aromasintez, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 25 ml, 50 ml or 100 ml bottle. |
Dosage Form, Packaging, and Composition
Solution for topical and external use in the form of a colorless, transparent or slightly opalescent liquid without odor.
| 1000 ml | |
| Chlorhexidine bigluconate | 2.5 ml |
Excipients : purified water – up to 1000 ml.
25 ml – dropper bottles (80) – cardboard boxes.
25 ml – dropper bottles (100) – cardboard boxes.
25 ml – dropper bottles (120) – cardboard boxes.
25 ml – dropper bottles (150) – cardboard boxes.
25 ml – dropper bottles (180) – cardboard boxes.
25 ml – dropper bottles (200) – cardboard boxes.
25 ml – dropper bottles (250) – cardboard boxes.
25 ml – dropper bottles (300) – cardboard boxes.
50 ml – dropper bottles (50) – cardboard boxes.
50 ml – dropper bottles (60) – cardboard boxes.
50 ml – dropper bottles (80) – cardboard boxes.
50 ml – dropper bottles (100) – cardboard boxes.
50 ml – dropper bottles (120) – cardboard boxes.
50 ml – dropper bottles (150) – cardboard boxes.
100 ml – dropper bottles (40) – cardboard boxes.
100 ml – dropper bottles (50) – cardboard boxes.
100 ml – dropper bottles (60) – cardboard boxes.
100 ml – dropper bottles (80) – cardboard boxes.
100 ml – dropper bottles (100) – cardboard boxes.
0.5 l – canisters (12) – cardboard boxes (for hospitals).
1 l – canisters (8) – cardboard boxes (for hospitals).
3 l – canisters (4) – cardboard boxes (for hospitals).
5 l – canisters (4) – cardboard boxes (for hospitals).
10 l – canisters (1) – cardboard boxes (for hospitals).
20 l – canisters (1) – cardboard boxes (for hospitals).
Solution for topical and external use 0.05%: 50 mL or 100 mL bottle 1 or 50 pcs., 1000 mL bottle
Marketing Authorization Holder
West, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 50 mL or 100 mL bottle 1 or 50 pcs., 1000 mL bottle |
Dosage Form, Packaging, and Composition
Solution for topical and external use 0.05% colorless or light yellow, transparent or slightly opalescent, odorless.
| 1 l | |
| Chlorhexidine bigluconate (in the form of a 20% solution) | 0.5 g |
Excipients : purified water – up to 1000 ml.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
1000 ml – bottles (1) – cardboard packs.
50 ml – bottles (50) – cardboard boxes (for hospitals).
100 ml – bottles (50) – cardboard boxes (for hospitals).
Solution for topical and external use 0.05%: 30 mL, 50 mL or 100 mL bottle
Marketing Authorization Holder
Dalkhimpharm, JSC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 30 mL, 50 mL or 100 mL bottle |
Dosage Form, Packaging, and Composition
Solution for topical and external use in the form of a colorless, transparent or slightly opalescent liquid without odor.
| 1000 ml | |
| Chlorhexidine bigluconate (in the form of a 20% solution) | 2.5 ml |
Excipients : purified water – up to 1000 ml.
30 ml – dropper bottles (1) – cardboard packs.
50 ml – dropper bottles (1) – cardboard packs.
100 ml – dropper bottles (1) – cardboard packs.
30 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
100 ml – orange glass bottles (1) – cardboard packs.
5 l – canisters (1) – cardboard boxes (for hospitals).
10 l – canisters (1) – cardboard boxes (for hospitals).
20 l – canisters (1) – cardboard boxes (for hospitals).
Solution for topical and external use 0.05%: 70 mL or 100 mL bottle, 1 L or 5 L polymer bottle
Marketing Authorization Holder
Ivanovo Pharmaceutical Factory PJSC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 70 mL or 100 mL bottle, 1 L or 5 L polymer bottle |
Dosage Form, Packaging, and Composition
Solution for topical and external use 0.05% in the form of a colorless transparent or slightly opalescent liquid.
| 100 ml | |
| Chlorhexidine bigluconate (in the form of a 20% solution) | 50 mg |
Excipients : purified water up to 1000 ml.
3 l – canisters (for hospitals).
5 l – canisters (for hospitals).
25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
80 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
Solution for topical and external use 0.05%: 70 ml or 100 ml bottle, 1 L or 5 L polymer bottle.
Marketing Authorization Holder
Rosbio, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 70 ml or 100 ml bottle, 1 L or 5 L polymer bottle. |
Dosage Form, Packaging, and Composition
| Solution for topical and external use 0.05% | 100 ml |
| Chlorhexidine bigluconate (in the form of a 20% solution) | 50 mg |
70 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.
100 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.
100 ml – dark glass bottles.
1 l – polymer bottles (for hospitals).
5 l – polymer bottles (for hospitals).
Solution for topical and external use 0.2%: 100 ml bottle, 1 L polymer bottle.
Marketing Authorization Holder
Rosbio, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.2%: 100 ml bottle, 1 L polymer bottle. |
Dosage Form, Packaging, and Composition
| Solution for topical and external use 0.2% | 100 ml |
| Chlorhexidine bigluconate (in the form of a 20% solution) | 200 mg |
100 ml – dark glass bottles.
100 ml – dark glass bottles (1) – cardboard packs.
1 l – polymer bottles (for hospitals).
Solution for topical and external use 0.5%: 100 ml bottle, 1 L polymer bottle.
Marketing Authorization Holder
Rosbio, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.5%: 100 ml bottle, 1 L polymer bottle. |
Dosage Form, Packaging, and Composition
| Solution for topical and external use 0.5% | 100 ml |
| Chlorhexidine bigluconate (as a 20% solution) | 500 mg |
100 ml – dark glass bottles (1) – cardboard packs.
100 ml – dark glass bottles.
1 L – polymer bottles (for hospitals).
Solution for topical and external use 1%: 100 ml bottle, 1 L polymer bottle.
Marketing Authorization Holder
Rosbio, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 1%: 100 ml bottle, 1 L polymer bottle. |
Dosage Form, Packaging, and Composition
| Solution for topical and external use 1% | 100 ml |
| Chlorhexidine bigluconate (as a 20% solution) | 1 g |
100 ml – dark glass bottles (1) – cardboard packs.
100 ml – dark glass bottles.
1 L – polymer bottles (for hospitals).
Solution for topical and external use 5%: 100 ml bottle.
Marketing Authorization Holder
Rosbio, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 5%: 100 ml bottle. |
Dosage Form, Packaging, and Composition
| Solution for topical and external use 5% | 100 ml |
| Chlorhexidine bigluconate (as a 20% solution) | 5 g |
100 ml – dark glass bottles (1) – cardboard packs.
Solution for topical and external use 0.05%: 80 mL or 100 mL bottle.
Marketing Authorization Holder
Tula Pharmaceutical Factory, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 80 mL or 100 mL bottle. |
Dosage Form, Packaging, and Composition
| Solution for topical and external use | 1000 ml |
| Chlorhexidine bigluconate (as a 20% solution) | 0.5 g |
Excipients: purified water up to 1000 ml.
100 ml – orange glass bottles (1) – cardboard packs.
80 ml – polymer bottles (1) with dropper nozzles – cardboard packs.
100 ml – polymer bottles (1) with dropper nozzles – cardboard packs.
Solution for topical and external use 0.05%: 80 mL or 100 mL bottle
Marketing Authorization Holder
Pharmregister LLC (Russia)
Manufactured By
Tula Pharmaceutical Factory, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 80 mL or 100 mL bottle |
Dosage Form, Packaging, and Composition
Solution for topical and external use as a colorless, transparent liquid without odor.
| 1000 ml | |
| Chlorhexidine bigluconate 20% solution* | 2.5 ml |
Excipients: purified water – up to 1000 ml.
*equivalent to chlorhexidine bigluconate content – 0.5 g
100 ml – orange glass bottles (1) – cardboard packs.
80 ml – polymer bottles (1) – cardboard packs.
100 ml – polymer bottles (1) – cardboard packs.
Solution for topical and external use 0.05%: 25 mL, 40 mL, 50 mL, 60 mL, 70 mL, 80 mL, 90 mL or 100 mL
Marketing Authorization Holder
Flora Kavkaza, JSC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 25 mL, 40 mL, 50 mL, 60 mL, 70 mL, 80 mL, 90 mL or 100 mL |
Dosage Form, Packaging, and Composition
Solution for topical and external use as a colorless, transparent or slightly opalescent liquid without odor.
| 1 L | |
| Chlorhexidine bigluconate | 2.5 ml |
Excipients: purified water – up to 1 L.
25 ml – bottles – cardboard packs.
25 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
40 ml – bottles – cardboard packs.
40 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
50 ml – bottles – cardboard packs.
50 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
60 ml – bottles – cardboard packs.
60 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
70 ml – bottles – cardboard packs.
70 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
80 ml – bottles – cardboard packs.
80 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
90 ml – bottles – cardboard packs.
90 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
100 ml – bottles – cardboard packs.
100 ml – bottles 20-200 pcs. – cardboard boxes (for hospitals).
Solution for topical and external use 0.05%: 80 mL or 100 mL bottle
Marketing Authorization Holder
Formula-FR, LLC (Russia)
Manufactured By
Tula Pharmaceutical Factory, LLC (Russia)
Dosage Form
|
Chlorhexidine bigluconate | Solution for topical and external use 0.05%: 80 mL or 100 mL bottle |
Dosage Form, Packaging, and Composition
Solution for topical and external use transparent, without odor.
| 1000 ml | |
| Chlorhexidine bigluconate (as a 20% solution) | 0.5 g |
Excipients: purified water – up to 1000 ml.
100 ml – orange glass bottles (1) – cardboard packs.
80 ml – polymer bottles (1) – cardboard packs.
100 ml – polymer bottles (1) – cardboard packs.
Vaginal suppositories 16 mg: 5 or 10 pcs.
Marketing Authorization Holder
Avexima JSC (Russia)
Manufactured By
Avexima Siberia LLC (Russia)
Dosage Form
|
Chlorhexidine Avexima | Vaginal suppositories 16 mg: 5 or 10 pcs. |
Dosage Form, Packaging, and Composition
Vaginal suppositories torpedo-shaped, white or white with a yellowish tint. Marbling and the presence of an air core and a funnel-shaped depression on the cut are allowed.
| 1 supp. | |
| Chlorhexidine bigluconate 20% solution | 85.2 mg |
| (calculated as chlorhexidine bigluconate) | 16 mg |
Excipients: macrogol 400 (polyethylene glycol 400), macrogol 1500 (polyethylene glycol 1500).
5 pcs. – contour cell packaging (1) – cardboard packs (1).
5 pcs. – contour cell packaging (2) – cardboard packs (1).
Solution for topical and external use 0.05%: 100 ml containers 50 or 75 pcs., 250 ml containers 24 or 36 pcs., 500 ml containers 12 or 18 pcs., 1000 ml containers 6 or 9 pcs., 1500 ml or 2000 ml containers 4 pcs.
Marketing Authorization Holder
Medsintez Plant, LLC (Russia)
Dosage Form
 |
Chlorhexidine C | Solution for topical and external use 0.05%: 100 ml containers 50 or 75 pcs., 250 ml containers 24 or 36 pcs., 500 ml containers 12 or 18 pcs., 1000 ml containers 6 or 9 pcs., 1500 ml or 2000 ml containers 4 pcs. |
Dosage Form, Packaging, and Composition
Solution for topical and external use colorless or light yellow, transparent, odorless or with a weak odor.
| 1 L | |
| Chlorhexidine bigluconate (substance-solution 20%) | 2.5 ml, |
| Which corresponds to the content of chlorhexidine bigluconate | 0.5 g |
Excipients: purified water – up to 1 L.
100 ml – containers (1) – polyethylene bags (50) – cardboard boxes.
100 ml – containers (1) – polyethylene bags (75) – cardboard boxes.
250 ml – containers (1) – polyethylene bags (24) – cardboard boxes.
250 ml – containers (1) – polyethylene bags (36) – cardboard boxes.
500 ml – containers (1) – polyethylene bags (12) – cardboard boxes.
500 ml – containers (1) – polyethylene bags (18) – cardboard boxes.
1000 ml – containers (1) – polyethylene bags (6) – cardboard boxes.
1000 ml – containers (1) – polyethylene bags (9) – cardboard boxes.
1500 ml – containers (1) – polyethylene bags (4) – cardboard boxes.
2000 ml – containers (1) – polyethylene bags (4) – cardboard boxes.
Solution for topical and external use 0.05%: 10 mL or 100 mL bottle.
Marketing Authorization Holder
Medisorb, JSC (Russia)
Dosage Form
|
Chlorhexidine Medisorb | Solution for topical and external use 0.05%: 10 mL or 100 mL bottle. |
Dosage Form, Packaging, and Composition
Solution for topical and external use colorless, transparent or slightly opalescent.
| 1000 ml | |
| Chlorhexidine bigluconate (20% solution) | 2.5 ml |
Excipients: purified water – up to 1000 ml.
10 ml – opaque polyethylene bottles, equipped with a spray nozzle (1) – cardboard packs.
100 ml – polyethylene terephthalate bottles equipped with a dropper nozzle (1) – cardboard packs.
Topical and external use spray 0.05%: 50 ml, 100 ml, or 150 ml bottle or dropper bottle
Marketing Authorization Holder
Ecolab, CJS (Russia)
Dosage Form
|
Chlorhexidine-ECOlab | Topical and external use spray 0.05%: 50 ml, 100 ml, or 150 ml bottle or dropper bottle |
Dosage Form, Packaging, and Composition
Spray for topical and external use as a colorless, transparent, slightly opalescent liquid, without odor.
| 1000 ml | |
| Chlorhexidine bigluconate (as a 20% solution) | 0.5 g |
Excipients: purified water – up to 1000 ml.
50 ml – bottles or dropper bottles – cardboard packs.
100 ml – bottles or dropper bottles – cardboard packs.
50 ml – bottles or dropper bottles – cardboard packs.
Vaginal suppositories 16 mg
Marketing Authorization Holder
Salvus, LLC (Russia)
Manufactured By
Rubicon, LLC (Republic of Belarus)
Dosage Form
|
Chlorhexidine-Salvus | Vaginal suppositories 16 mg |
Dosage Form, Packaging, and Composition
Vaginal suppositories
| 1 supp. | |
| Chlorhexidine (as bigluconate) | 16 mg |
5 pcs. – contour cell packaging – cardboard packs (5 pcs.) – Over-the-Counter
5 pcs. – contour cell packaging (2 pcs.) – cardboard packs (10 pcs.) – Over-the-Counter
Solution for topical and external use 0.02%: 500 mL bottles
Marketing Authorization Holder
Sphere-Pharm, LLC (Russia)
Dosage Form
|
Chlorhexidine-SF | Solution for topical and external use 0.02%: 500 mL bottles |
Dosage Form, Packaging, and Composition
Solution for topical and external use as a colorless, transparent or slightly opalescent liquid.
| 1 L | |
| Chlorhexidine bigluconate (as a 20% solution) | 1 ml |
Excipients: purified water – up to 1 L.
500 ml – bottles (1) – cardboard packs.
500 ml – bottles (16) – cardboard boxes (for hospitals).
500 ml – containers (18) – cardboard boxes (for hospitals).
1000 ml – containers (6) – cardboard boxes (for hospitals).
2000 ml – containers (4) – cardboard boxes (for hospitals).
![Chlorhexidine bigluconate [Solution, Spray, Suppositories] 1](https://www.medixlife.com/wp-content/uploads/Medixlife_favi_512.png "Chlorhexidine bigluconate [Solution, Spray, Suppositories] 2")