Mastodon

Chlorhexidine (Solution, Spray, Suppositories) Instructions for Use

ATC Code

D08AC02 (Chlorhexidine)

Active Substance

Chlorhexidine (Rec.INN registered by WHO)

Clinical-Pharmacological Group

Antiseptic for external and topical use

Pharmacotherapeutic Group

Antiseptic

Pharmacological Action

An antiseptic agent with a predominantly bactericidal action. Depending on the concentration used, Chlorhexidine exhibits a bacteriostatic or bactericidal effect against gram-positive and gram-negative bacteria.

Bacteriostatic action is manifested at a concentration of 0.01% or less; bactericidal – at a concentration of 0.01% at a temperature of 22°C (71.6°F) and exposure for 1 min; fungicidal action at a concentration of 0.05%, temperature of 22°C (71.6°F) and exposure for 10 min; virucidal action (against lipophilic viruses) is manifested at a concentration of 0.01-1%.

It acts on bacterial spores only at elevated temperatures. It is stable; after skin treatment, it remains on it in a certain amount sufficient to manifest a bactericidal effect. It retains activity (although somewhat reduced) in the presence of blood, pus, various secretions, and organic substances.

It does not have a damaging effect on items made of glass, plastic, and metals.

Pharmacokinetics

When applied externally and topically, it is not absorbed into the systemic circulation and does not have a systemic effect.

Indications

As a therapeutic and prophylactic agent for various infections, for aseptic treatment and disinfection.

For external use: treatment of wounds, burn wounds and surfaces; disinfection of the patient’s skin.

For external and topical use: bacterial and fungal diseases of the skin and mucous membranes in surgery, urology, obstetrics and gynecology, dentistry (gingivitis, stomatitis, aphthae, periodontitis, alveolitis); prevention of sexually transmitted diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis).

For use in dentistry and ENT practice: gingivitis, stomatitis, aphthae, periodontitis, alveolitis, disinfection of removable dentures; angina; postoperative care for patients in ENT and dentistry departments.

For vaginal use: trichomonas colpitis, cervical erosion, vulvar itching, prevention of sexually transmitted diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis); prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment of gynecological diseases, before childbirth, abortion, before and after insertion of an IUD, before and after diathermocoagulation of the cervix, before intrauterine examinations); treatment of bacterial vaginosis, colpitis (including nonspecific, mixed, trichomonas).

Treatment of the surgeon’s hands, medical personnel, and the surgical field before diagnostic manipulations and surgery.

Disinfection of working surfaces of devices (including thermometers) and equipment for which thermal treatment is undesirable.

In the form of an alcoholic solution

Hygienic treatment of the hands of medical personnel, surgeons’ hands, for treatment of the surgical and injection fields, the elbow bend of a donor; disinfection of small-area surfaces of medical products, including dental instruments (for which thermal treatment is undesirable) in healthcare facilities. Hygienic hand treatment in healthcare facilities. Hygienic hand treatment of medical personnel of institutions of various profiles and purposes.

ICD codes

ICD-10 code Indication
A50 Congenital syphilis
A51 Early syphilis
A52 Late syphilis
A54 Gonococcal infection
A56.0 Chlamydial infections of lower genitourinary tract
A56.1 Chlamydial infections of pelvic organs and other genitourinary organs
A59 Trichomoniasis
J02 Acute pharyngitis
J03 Acute tonsillitis
J31.2 Chronic pharyngitis
J35.0 Chronic tonsillitis
K04 Diseases of pulp and periapical tissues (including periodontitis)
K05 Gingivitis and periodontal diseases
K10.3 Alveolitis of jaws
K12 Stomatitis and related lesions
L29.2 Pruritus vulvae
N34 Urethritis and urethral syndrome
N37.0 Urethritis in diseases classified elsewhere
N72 Inflammatory disease of cervix uteri (including cervicitis, endocervicitis, exocervicitis)
N76 Other inflammatory diseases of vagina and vulva
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
N86 Erosion and ectropion of cervix
N89.8 Other noninflammatory disorders of vagina
T14.0 Superficial injury of unspecified body region (including abrasion, bruise, contusion, hematoma, bite of nonvenomous insect)
T14.1 Open wound of unspecified body region
T30 Burns and corrosions of unspecified body region
T79.3 Posttraumatic wound infection, not elsewhere classified
Z29.8 Other specified prophylactic measures
Z51.4 Preparatory procedures for subsequent treatment or examination, not elsewhere classified
Z97.2 Presence of dental prosthesis
ICD-11 code Indication
1A60.Z Congenital syphilis, unspecified
1A61.Z Early syphilis, unspecified
1A62.Z Late syphilis, unspecified
1A7Z Gonococcal infection, unspecified
1A81.0 Chlamydial infection of lower genitourinary tract
1A81.1 Chlamydial infection of internal reproductive organs
1A92 Trichomoniasis
1F23.10 Candidiasis of vulva and vagina
1F65 Enterobiasis
1H0Z Unspecified infection
CA02.Z Acute pharyngitis, unspecified
CA03.Z Acute tonsillitis, unspecified
CA09.2 Chronic pharyngitis
CA0F.Y Other specified chronic diseases of the palatine tonsils and adenoids
DA01.Z Diseases of the oral mucosa, unspecified
DA06.1 Alveolitis of jaw
DA09.Z Diseases of pulp and periapical tissues, unspecified
DA0B.Z Gingival diseases, unspecified
DA0C.Z Periodontal diseases, unspecified
DA0Z Diseases or disorders of the orofacial complex, unspecified
EH92 Dermatoses provoked by friction or mechanical impact
EH92.1 Blister due to friction
GA00 Vulvitis
GA02.Z Unspecified vaginitis
GA0Z Inflammatory diseases of female genital tract, unspecified
GA15.1 Erosion or ectropion of cervix
GA42.0 Pruritus vulvae
GC02.1 Nonspecific urethritis
GC02.Z Urethritis and urethral syndrome, unspecified
GC42.1 Painful intercourse
MF3A Vaginal discharge
ND56.0 Superficial injury of unspecified body region
ND56.1 Open wound of unspecified body region
NE11 Burn of unspecified body region
NF0A.3 Posttraumatic wound infection, not elsewhere classified
QB51.A Presence of dental prosthetic device
QB9A Preparatory procedures for subsequent treatment
QC05.Z Prophylactic measures, unspecified
1A94.0 Genital or urogenital tract infection caused by Herpes simplex virus
GA41 Ulcerative or erosive diseases of vulva
GA0Z Inflammatory diseases of female genital tract, unspecified
XA5WW1 Cervix uteri
GA1Z Unspecified noninflammatory disorders of female genital tract
XA1LK7 Vagina

Dosage Regimen

The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen.

Apply the 0.05%, 0.2% aqueous solution for gingivitis, stomatitis, aphthae, periodontitis, and alveolitis; use as a mouthwash or gargle 2-3 times daily.

Irrigate or rinse the oral cavity for 30-60 seconds; avoid eating or drinking for at least 30 minutes after application.

Use the 0.05% solution for wound treatment and disinfection of burn surfaces; apply to the affected area via irrigation, compress, or tamponade.

For disinfection of the surgical field and surgeon’s hands, use a 0.5% alcohol solution; apply according to standard surgical scrubbing protocols.

For prevention of sexually transmitted diseases, apply the 0.05% solution to genital skin and mucous membranes; use within 2 hours after sexual contact.

For vaginal suppositories, administer one suppository (16 mg or 8 mg) intravaginally, once or twice daily for 7-10 days; follow the specific prescribed course for trichomonas colpitis, bacterial vaginosis, or preoperative preparation.

For cervical erosion, use vaginal suppositories as an adjunct therapy; administer one suppository daily for the duration prescribed, typically 10-14 days.

Apply the spray form for skin antisepsis; hold the container 15-20 cm from the skin and spray for 1-3 seconds to cover the entire area.

For disinfection of removable dentures, soak them in a 0.2% aqueous solution; the duration of soaking depends on the clinical indication and material compatibility.

Use the 0.5% alcohol solution for hygienic hand treatment of medical personnel; apply 3-5 ml and rub into skin for 1-2 minutes.

For disinfection of medical equipment (e.g., thermometers), wipe or immerse items in the appropriate concentration solution; ensure complete surface contact.

Strictly adhere to the indication-specific concentration; do not interchange formulations not intended for a specific use.

Adverse Reactions

Depending on the dosage form used, the following adverse reactions develop very rarely.

Allergic reactions: skin rash, itching, severe allergic reactions, including anaphylaxis.

Skin and subcutaneous tissue disorders: dry skin, itching, dermatitis, photosensitivity.

Local reactions: staining of tooth enamel, tartar deposition, taste disturbance.

With vaginal use allergic reactions (rash, itching), burning are possible; very rarely – anaphylactic reactions; in some cases – bloody discharge from the vagina.

Contraindications

Hypersensitivity to chlorhexidine.

Use in Pregnancy and Lactation

If it is necessary to use during pregnancy and breastfeeding, the expected benefit of therapy for the mother and the possible risk to the fetus should be weighed.

Pediatric Use

Should be used with caution in children.

Special Precautions

Chlorhexidine must not be allowed to get into the eyes (except for a special dosage form intended for use in ophthalmology), as well as contact with the meninges and the auditory nerve.

With intravaginal use, in case of bloody discharge from the vagina, the use of chlorhexidine should be discontinued.

Drug Interactions

It is used in a neutral environment; at pH 5-8 the difference in activity is small; at pH above 8, a precipitate forms.

It is not used in combination with anionic compounds, including soap.

It is incompatible with carbonates, chlorides, phosphates, borates, sulfates, and citrates.

The use of hard water reduces bactericidal properties.

It is compatible with medicinal products containing a cationic group (benzalkonium chloride, cetrimonium bromide).

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.

Medical Disclaimer

Brand (or Active Substance), Marketing Authorisation Holder, Dosage Form

Marketing Authorization Holder

Akapharm, LLC (Russia)

Dosage Forms

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.02%: bottles 100 ml, 200 ml, 250 ml, 300 ml, 350 ml, 400 ml, 450 ml or 500 ml
Solution for topical and external use 0.2%: bottles 100 ml, 200 ml, 250 ml, 300 ml, 350 ml, 400 ml, 450 ml or 500 ml
Solution for topical and external use 0.05%: bottles 100 ml, 200 ml, 250 ml, 300 ml, 350 ml, 400 ml, 450 ml or 500 ml
Solution for topical and external use 0.5%: 100 ml, 200 ml, 250 ml, 300 ml, 350 ml, 400 ml, 450 ml, or 500 ml bottle

Dosage Form, Packaging, and Composition

Solution for topical and external use as a colorless, transparent or slightly opalescent liquid.

1000 ml
Chlorhexidine digluconate (20% solution) 1 ml,
   Which corresponds to the content of chlorhexidine digluconate 0.2 g

Excipients : purified water – up to 1000 ml.

100 ml – bottles (1) – cardboard packs.
200 ml – bottles (1) – cardboard packs.
250 ml – bottles (1) – cardboard packs.
300 ml – bottles (1) – cardboard packs.
350 ml – bottles (1) – cardboard packs.
400 ml – bottles (1) – cardboard packs.
450 ml – bottles (1) – cardboard packs.
500 ml – bottles (1) – cardboard packs.
500 ml – containers (1) – polyethylene bags.
1000 ml – containers (1) – polyethylene bags.
3000 ml – containers (1) – polyethylene bags (for hospitals).
5000 ml – containers (1) – polyethylene bags (for hospitals).


Solution for topical and external use as a colorless, transparent or slightly opalescent liquid.

1000 ml
Chlorhexidine digluconate (20% solution) 10 ml,
   Which corresponds to the content of chlorhexidine digluconate 2 g

Excipients : purified water – up to 1000 ml.

100 ml – bottles (1) – cardboard packs.
200 ml – bottles (1) – cardboard packs.
250 ml – bottles (1) – cardboard packs.
300 ml – bottles (1) – cardboard packs.
350 ml – bottles (1) – cardboard packs.
400 ml – bottles (1) – cardboard packs.
450 ml – bottles (1) – cardboard packs.
500 ml – bottles (1) – cardboard packs.
500 ml – containers (1) – polyethylene bags.
1000 ml – containers (1) – polyethylene bags.
3000 ml – containers (1) – polyethylene bags (for hospitals).
5000 ml – containers (1) – polyethylene bags (for hospitals).


Solution for topical and external use as a colorless, transparent or slightly opalescent liquid.

1000 ml
Chlorhexidine digluconate (20% solution) 2.5 ml,
   Which corresponds to the content of chlorhexidine digluconate 0.5 g

Excipients : purified water – up to 1000 ml.

100 ml – bottles (1) – cardboard packs.
200 ml – bottles (1) – cardboard packs.
250 ml – bottles (1) – cardboard packs.
300 ml – bottles (1) – cardboard packs.
350 ml – bottles (1) – cardboard packs.
400 ml – bottles (1) – cardboard packs.
450 ml – bottles (1) – cardboard packs.
500 ml – bottles (1) – cardboard packs.
500 ml – containers (1) – polyethylene bags.
1000 ml – containers (1) – polyethylene bags.
3000 ml – containers (1) – polyethylene bags (for hospitals).
5000 ml – containers (1) – polyethylene bags (for hospitals).


Solution for topical and external use as a colorless, transparent or slightly opalescent liquid.

1000 ml
Chlorhexidine digluconate (20% solution) 25 ml,
   Which corresponds to the content of chlorhexidine digluconate 5 g

Excipients : purified water – up to 1000 ml.

100 ml – bottles (1) – cardboard packs.
200 ml – bottles (1) – cardboard packs.
250 ml – bottles (1) – cardboard packs.
300 ml – bottles (1) – cardboard packs.
350 ml – bottles (1) – cardboard packs.
400 ml – bottles (1) – cardboard packs.
450 ml – bottles (1) – cardboard packs.
500 ml – bottles (1) – cardboard packs.
500 ml – containers (1) – polyethylene bags.
1000 ml – containers (1) – polyethylene bags.
3000 ml – containers (1) – polyethylene bags (for hospitals).
5000 ml – containers (1) – polyethylene bags (for hospitals).

Marketing Authorization Holder

Activa, JSC (Russia)

Manufactured By

Activa, JSC (Russia)

Or

RFK, CJS (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for external use (alcoholic) 0.5%: bottles 50 ml, 100 ml, 500 ml or 1000 ml.

Dosage Form, Packaging, and Composition

Solution for external use as a colorless or light yellow, transparent or slightly opalescent liquid, with a characteristic smell of alcohol.

1000 ml
Chlorhexidine digluconate (20% solution) 25 ml

Excipients : ethyl alcohol 70% – up to 1000 ml.

50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
500 ml – bottles (1) – cardboard packs.
1000 ml – bottles (1) – cardboard packs.
1 l – polyethylene canisters (for hospitals).
3 l – polyethylene canisters (for hospitals).
5 l – polyethylene canisters (for hospitals).
10 l – polyethylene canisters (for hospitals).
20 l – polyethylene canisters (for hospitals).
25 l – polyethylene canisters (for hospitals).
50 l – polyethylene canisters (for hospitals).

Marketing Authorization Holder

Alvils, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 100 ml bottles 50 pcs.; 500 ml or 1000 ml bottles 6, 8 or 12 pcs.; 225 ml, 250 ml, 425 ml or 450 ml bottles 6, 8 or 12 pcs.; 3 L, 5 L or 10 L canisters 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% is colorless or light yellow, transparent, odorless or with a faint odor.

1 L
Chlorhexidine bigluconate (in the form of a 20% solution) 0.5 g

Excipients: purified water – up to 1000 ml.

100 ml – plastic bottles (1) – cardboard packs (50) – cardboard boxes.
500 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
225 ml – glass bottles (6) – cardboard boxes (for hospitals).
225 ml – glass bottles (8) – cardboard boxes (for hospitals).
225 ml – glass bottles (12) – cardboard boxes (for hospitals).
250 ml – glass bottles (6) – cardboard boxes (for hospitals).
250 ml – glass bottles (8) – cardboard boxes (for hospitals).
250 ml – glass bottles (12) – cardboard boxes (for hospitals).
425 ml – glass bottles (6) – cardboard boxes (for hospitals).
425 ml – glass bottles (8) – cardboard boxes (for hospitals).
425 ml – glass bottles (12) – cardboard boxes (for hospitals).
450 ml – glass bottles (6) – cardboard boxes (for hospitals).
450 ml – glass bottles (8) – cardboard boxes (for hospitals).
450 ml – glass bottles (12) – cardboard boxes (for hospitals).
3 L – polyethylene canisters (4) – cardboard boxes.
5 L – polyethylene canisters (4) – cardboard boxes.
10 L – polyethylene canisters (4) – cardboard boxes.

Marketing Authorization Holder

Alvils, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: 100 ml bottles 50 pcs.; 500 ml or 1000 ml bottles 6, 8 or 12 pcs.; 225 ml, 250 ml, 425 ml or 450 ml bottles 6, 8 or 12 pcs.; 3 L, 5 L or 10 L canisters 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.2% is colorless or light yellow, transparent, odorless or with a faint odor.

1 L
Chlorhexidine bigluconate (in the form of a 20% solution) 2 g

Excipients: purified water – up to 1000 ml.

100 ml – plastic bottles (1) – cardboard packs (50) – cardboard boxes.
500 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
225 ml – glass bottles (6) – cardboard boxes (for hospitals).
225 ml – glass bottles (8) – cardboard boxes (for hospitals).
225 ml – glass bottles (12) – cardboard boxes (for hospitals).
250 ml – glass bottles (6) – cardboard boxes (for hospitals).
250 ml – glass bottles (8) – cardboard boxes (for hospitals).
250 ml – glass bottles (12) – cardboard boxes (for hospitals).
425 ml – glass bottles (6) – cardboard boxes (for hospitals).
425 ml – glass bottles (8) – cardboard boxes (for hospitals).
425 ml – glass bottles (12) – cardboard boxes (for hospitals).
450 ml – glass bottles (6) – cardboard boxes (for hospitals).
450 ml – glass bottles (8) – cardboard boxes (for hospitals).
450 ml – glass bottles (12) – cardboard boxes (for hospitals).
3 L – polyethylene canisters (4) – cardboard boxes.
5 L – polyethylene canisters (4) – cardboard boxes.
10 L – polyethylene canisters (4) – cardboard boxes.

Marketing Authorization Holder

Alvils, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: 100 ml bottles 50 pcs.; 500 ml or 1000 ml bottles 6, 8 or 12 pcs.; 225 ml, 250 ml, 425 ml or 450 ml bottles 6, 8 or 12 pcs.; 3 L, 5 L or 10 L canisters 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.5% is colorless or light yellow, transparent, odorless or with a faint odor.

1 L
Chlorhexidine bigluconate (in the form of a 20% solution) 5 g

Excipients: purified water – up to 1000 ml.

100 ml – plastic bottles (1) – cardboard packs (50) – cardboard boxes.
500 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
225 ml – glass bottles (6) – cardboard boxes (for hospitals).
225 ml – glass bottles (8) – cardboard boxes (for hospitals).
225 ml – glass bottles (12) – cardboard boxes (for hospitals).
250 ml – glass bottles (6) – cardboard boxes (for hospitals).
250 ml – glass bottles (8) – cardboard boxes (for hospitals).
250 ml – glass bottles (12) – cardboard boxes (for hospitals).
425 ml – glass bottles (6) – cardboard boxes (for hospitals).
425 ml – glass bottles (8) – cardboard boxes (for hospitals).
425 ml – glass bottles (12) – cardboard boxes (for hospitals).
450 ml – glass bottles (6) – cardboard boxes (for hospitals).
450 ml – glass bottles (8) – cardboard boxes (for hospitals).
450 ml – glass bottles (12) – cardboard boxes (for hospitals).
3 L – polyethylene canisters (4) – cardboard boxes.
5 L – polyethylene canisters (4) – cardboard boxes.
10 L – polyethylene canisters (4) – cardboard boxes.

Marketing Authorization Holder

Alvils, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 1%: 100 ml bottles 50 pcs.; 500 ml or 1000 ml bottles 6, 8 or 12 pcs.; 225 ml, 250 ml, 425 ml or 450 ml bottles 6, 8 or 12 pcs.; 3 L, 5 L or 10 L canisters 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 1% is colorless or light yellow, transparent, odorless or with a faint odor.

1 L
Chlorhexidine bigluconate (in the form of a 20% solution) 10 g

Excipients: purified water – up to 1000 ml.

100 ml – plastic bottles (1) – cardboard packs (50) – cardboard boxes.
500 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
225 ml – glass bottles (6) – cardboard boxes (for hospitals).
225 ml – glass bottles (8) – cardboard boxes (for hospitals).
225 ml – glass bottles (12) – cardboard boxes (for hospitals).
250 ml – glass bottles (6) – cardboard boxes (for hospitals).
250 ml – glass bottles (8) – cardboard boxes (for hospitals).
250 ml – glass bottles (12) – cardboard boxes (for hospitals).
425 ml – glass bottles (6) – cardboard boxes (for hospitals).
425 ml – glass bottles (8) – cardboard boxes (for hospitals).
425 ml – glass bottles (12) – cardboard boxes (for hospitals).
450 ml – glass bottles (6) – cardboard boxes (for hospitals).
450 ml – glass bottles (8) – cardboard boxes (for hospitals).
450 ml – glass bottles (12) – cardboard boxes (for hospitals).
3 L – polyethylene canisters (4) – cardboard boxes.
5 L – polyethylene canisters (4) – cardboard boxes.
10 L – polyethylene canisters (4) – cardboard boxes.

Marketing Authorization Holder

Alvils, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 5%: bottles 100 ml 50 pcs.; bottles 500 ml or 1000 ml 6, 8 or 12 pcs.; bottles 225 ml, 250 ml, 425 ml or 450 ml 6, 8 or 12 pcs.; canisters 3 l, 5 l or 10 l 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 5% is colorless or light yellow, transparent, odorless or with a faint odor.

1 L
Chlorhexidine bigluconate (in the form of a 20% solution) 50 g

Excipients: purified water – up to 1000 ml.

100 ml – plastic bottles (1) – cardboard packs (50) – cardboard boxes.
500 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
500 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (6) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (8) – cardboard boxes (for hospitals).
1000 ml – polyethylene terephthalate bottles (12) – cardboard boxes (for hospitals).
225 ml – glass bottles (6) – cardboard boxes (for hospitals).
225 ml – glass bottles (8) – cardboard boxes (for hospitals).
225 ml – glass bottles (12) – cardboard boxes (for hospitals).
250 ml – glass bottles (6) – cardboard boxes (for hospitals).
250 ml – glass bottles (8) – cardboard boxes (for hospitals).
250 ml – glass bottles (12) – cardboard boxes (for hospitals).
425 ml – glass bottles (6) – cardboard boxes (for hospitals).
425 ml – glass bottles (8) – cardboard boxes (for hospitals).
425 ml – glass bottles (12) – cardboard boxes (for hospitals).
450 ml – glass bottles (6) – cardboard boxes (for hospitals).
450 ml – glass bottles (8) – cardboard boxes (for hospitals).
450 ml – glass bottles (12) – cardboard boxes (for hospitals).
3 L – polyethylene canisters (4) – cardboard boxes.
5 L – polyethylene canisters (4) – cardboard boxes.
10 L – polyethylene canisters (4) – cardboard boxes.

Marketing Authorization Holder

Allians, LLC (Russia)

Manufactured By

Armavir Interdistrict Pharmacy Base, PJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 50 ml or 100 ml bottle

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% is a transparent colorless or light yellow liquid, odorless.

1000 ml
Chlorhexidine bigluconate (20% solution) 2.5 ml,
   Which corresponds to the content of chlorhexidine bigluconate 0.5 g

Excipients: purified water – 1000 ml.

50 ml – polyethylene terephthalate bottles (1) – cardboard packs.
100 ml – polyethylene terephthalate bottles (1) – cardboard packs.
50 ml – orange glass bottles (1) – cardboard packs.

Marketing Authorization Holder

Biogen NPTs OU (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: bottle 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, or 1000 ml; carboys 3 L or 5 L; canisters 3 L or 5 L

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% is colorless or light yellow, transparent, slightly opalescent, odorless or with a faint odor.

100 ml
Chlorhexidine bigluconate (in the form of a 20% solution) 50 mg

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles.
50 ml – polyethylene bottles.
70 ml – polyethylene bottles.
100 ml – polyethylene bottles.
200 ml – polyethylene bottles.
500 ml – polyethylene bottles.
1000 ml – polyethylene bottles.
3 L – carboys.
5 L – carboys.
3 L – polyethylene canisters.
5 L – polyethylene canisters.

Marketing Authorization Holder

Biogen NPTs OU (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: bottle 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, or 1000 ml; carboys 3 L or 5 L; canisters 3 L or 5 L

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.2% is colorless or light yellow, transparent, slightly opalescent, odorless or with a faint odor.

100 ml
Chlorhexidine bigluconate (in the form of a 20% solution) 200 mg

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles.
50 ml – polyethylene bottles.
70 ml – polyethylene bottles.
100 ml – polyethylene bottles.
200 ml – polyethylene bottles.
500 ml – polyethylene bottles.
1000 ml – polyethylene bottles.
3 L – carboys.
5 L – carboys.
3 L – polyethylene canisters.
5 L – polyethylene canisters.

Marketing Authorization Holder

Biogen NPTs OU (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: bottle 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, or 1000 ml; carboys 3 L or 5 L; canisters 3 L or 5 L.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.5% colorless or light yellow, transparent, slightly opalescent, odorless or with a faint odor.

100 ml
Chlorhexidine digluconate (as a 20% solution) 500 mg

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles.
50 ml – polyethylene bottles.
70 ml – polyethylene bottles.
100 ml – polyethylene bottles.
200 ml – polyethylene bottles.
500 ml – polyethylene bottles.
1000 ml – polyethylene bottles.
3 L – carboys.
5 L – carboys.
3 L – polyethylene canisters.
5 L – polyethylene canisters.

Marketing Authorization Holder

Biogen NPTs OU (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 1%: bottle 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, or 1000 ml; carboys 3 L or 5 L; canisters 3 L or 5 L

Dosage Form, Packaging, and Composition

Solution for topical and external use 1% colorless or light yellow, transparent, slightly opalescent, odorless or with a faint odor.

100 ml
Chlorhexidine digluconate (as a 20% solution) 1 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles.
50 ml – polyethylene bottles.
70 ml – polyethylene bottles.
100 ml – polyethylene bottles.
200 ml – polyethylene bottles.
500 ml – polyethylene bottles.
1000 ml – polyethylene bottles.
3 L – carboys.
5 L – carboys.
3 L – polyethylene canisters.
5 L – polyethylene canisters.

Marketing Authorization Holder

Biogen NPTs OU (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 5%: bottle 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, or 1000 ml; carboys 3 L or 5 L; canisters 3 L or 5 L

Dosage Form, Packaging, and Composition

Solution for topical and external use 5% colorless or light yellow, transparent, slightly opalescent, odorless or with a faint odor.

100 ml
Chlorhexidine digluconate (as a 20% solution) 5 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles.
50 ml – polyethylene bottles.
70 ml – polyethylene bottles.
100 ml – polyethylene bottles.
200 ml – polyethylene bottles.
500 ml – polyethylene bottles.
1000 ml – polyethylene bottles.
3 L – carboys.
5 L – carboys.
3 L – polyethylene canisters.
5 L – polyethylene canisters.

Marketing Authorization Holder

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.2% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (as a 20% solution) 2 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.5% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (as a 20% solution) 5 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 1%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.2% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (as a 20% solution) 10 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 5%: 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; 3 kg, 5 kg, 10 kg, or 20 kg canisters 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 5% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (as a 20% solution) 50 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (as a 20% solution) 0.5 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

B-PHARM, LLC (Russia)

Manufactured By

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 5, 10, or 15 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed; presence of an air core and a funnel-shaped depression is possible.

1 supp.
Chlorhexidine digluconate, substance-solution 20% 80 mg,
   Equivalent to chlorhexidine digluconate content 16 mg

Excipients: macrogol 1500 – 2869 mg, macrogol 400 – 151 mg.

5 pcs. – contour cell packs – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (3) – cardboard packs.

Marketing Authorization Holder

Vita Line, LLC (Russia)

Manufactured By

Tula Pharmaceutical Factory, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 4, 5, 6, 8, 10, or 12 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine digluconate solution 20% 85.2 mg,
   Equivalent to chlorhexidine digluconate content 16 mg

Excipients: macrogol 1500 – 2533.3 mg, macrogol 400 (polyethylene glycol 400) – 225.2 mg, macrogol 4000 (polyethylene glycol 4000) – 56.3 mg.

4 pcs. – contour cell packs (1) – cardboard packs.
4 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
6 pcs. – contour cell packs (1) – cardboard packs.
6 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Medsintez Plant, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 100 ml containers 50 or 75 pcs., 250 ml containers 24 or 36 pcs., 500 ml containers 12 or 18 pcs., 1000 ml containers 6 or 9 pcs., 1500 ml or 2000 ml containers 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use colorless or light yellow, transparent, odorless or with a faint odor.

1 L
Chlorhexidine digluconate (as a 20% solution) 0.5 g

Excipients: purified water up to 1 L.

100 ml – polymer containers (1) – polymer bags (50) – cardboard boxes (for hospitals).
100 ml – polymer containers (1) – polymer bags (75) – cardboard boxes (for hospitals).
250 ml – polymer containers (1) – polymer bags (24) – cardboard boxes (for hospitals).
250 ml – polymer containers (1) – polymer bags (36) – cardboard boxes (for hospitals).
500 ml – polymer containers (1) – polymer bags (12) – cardboard boxes (for hospitals).
500 ml – polymer containers (1) – polymer bags (18) – cardboard boxes (for hospitals).
1000 ml – polymer containers (1) – polymer bags (6) – cardboard boxes (for hospitals).
1000 ml – polymer containers (1) – polymer bags (9) – cardboard boxes (for hospitals).
1500 ml – polymer containers (1) – polymer bags (4) – cardboard boxes (for hospitals).
2000 ml – polymer containers (1) – polymer bags (4) – cardboard boxes (for hospitals).

Marketing Authorization Holder

Kemerovo Pharmaceutical Factory JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 25 ml, 50 ml, 70 ml, 100 ml or 200 ml bottles, 1 L, 3 L, 5 L, 10 L, or 20 L canisters

Dosage Form, Packaging, and Composition

Solution for topical and external use colorless, transparent or slightly opalescent, odorless.

1000 ml
Chlorhexidine digluconate (20% solution) 2.5 ml

50 ml – dark glass bottles (1) – cardboard packs.
100 ml – dark glass bottles (1) – cardboard packs.
25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
70 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene terephthalate bottles (1) – cardboard packs.
50 ml – polyethylene terephthalate bottles (1) – cardboard packs.
100 ml – polyethylene terephthalate bottles (1) – cardboard packs.
1 L – polyethylene canisters.
3 L – polyethylene canisters.
5 L – polyethylene canisters.
10 L – polyethylene canisters.
20 L – polyethylene canisters.

Marketing Authorization Holder

Lekar, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: bottle 50 ml, 70 ml, 90 ml, 100 ml, or 1 L; canisters 3 L, 5 L, or 10 L

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% 100 ml
Chlorhexidine digluconate 50 mg
(in the form of a 20% solution)

50 ml – polyethylene bottles (1) – cardboard packs.
70 ml – polyethylene bottles (1) – cardboard packs.
90 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
1 L – polyethylene bottles (1) – cardboard packs.
3 L – polyethylene canisters.
5 L – polyethylene canisters.
10 L – polyethylene canisters.

Marketing Authorization Holder

Lekar, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Topical and external use spray 0.05%: 25 ml, 30 ml, 40 ml, 50 ml, 75 ml, 100 ml, 150 ml, 200 ml, or 250 ml bottle

Dosage Form, Packaging, and Composition

Spray for topical and external use in the form of a colorless, transparent, slightly opalescent liquid, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (in the form of a 20% solution) 0.5 g

Excipients: purified water – up to 1000 ml.

25 ml – bottles – cardboard packs.
30 ml – bottles – cardboard packs.
40 ml – bottles – cardboard packs.
50 ml – bottles – cardboard packs.
75 ml – bottles – cardboard packs.
100 ml – bottles – cardboard packs.
150 ml – bottles – cardboard packs.
200 ml – bottles – cardboard packs.
250 ml – bottles – cardboard packs.

Marketing Authorization Holder

Lekar, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Gargle solution 0.05%: 50 ml, 100 ml, 150 ml, 200 ml, or 250 ml bottle

Dosage Form, Packaging, and Composition

Gargle solution in the form of a colorless, transparent or slightly opalescent liquid, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate 0.5 g

Excipients: purified water – up to 1000 ml.

50 ml – bottles – cardboard packs.
100 ml – bottles – cardboard packs.
150 ml – bottles – cardboard packs.
200 ml – bottles – cardboard packs.
250 ml – bottles – cardboard packs.

Marketing Authorization Holder

Marbiopharm, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: 25 ml, 50 ml, 100 ml, 500 ml or 1000 ml bottle.

Dosage Form, Packaging, and Composition

Alcohol solution for external use colorless or light yellow, transparent or slightly opalescent, with a characteristic odor.

1000 ml
Chlorhexidine digluconate 5 g
   Which corresponds to the content of chlorhexidine digluconate (20% solution) 25 ml

Excipients: ethanol (ethyl alcohol 95%) – 718.5 ml, purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
25 ml – dropper bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
50 ml – dropper bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
100 ml – dropper bottles (1) – cardboard packs.
500 ml – bottles – cardboard packs.
1000 ml – bottles – cardboard packs.

Marketing Authorization Holder

Medkhimprom Pharmchemical Company, OJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (in the form of a 20% solution) 0.5 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Medkhimprom Pharmchemical Company, OJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.2% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (in the form of a 20% solution) 2 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Medkhimprom Pharmchemical Company, OJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.5% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (in the form of a 20% solution) 5 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Medkhimprom Pharmchemical Company, OJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 1%: fl. 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; canisters 3 kg, 5 kg, 10 kg or 20 kg 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 1% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (in the form of a 20% solution) 10 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Medkhimprom Pharmchemical Company, OJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 5%: 25 ml, 50 ml 1 or 70 pcs., 100 ml 1 or 40 pcs., 500 ml 12 pcs., 1000 ml 8 pcs.; 3 kg, 5 kg, 10 kg, or 20 kg canisters 4 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 5% colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (in the form of a 20% solution) 50 g

Excipients: purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard packs.
50 ml – polyethylene bottles (70) – cardboard packs.
100 ml – polyethylene bottles (40) – cardboard packs.
500 ml – polyethylene bottles (12) – cardboard boxes.
1000 ml – polyethylene bottles (8) – cardboard boxes.
3 kg – polyethylene canisters (4) – polyethylene film.
5 kg – polyethylene canisters (4) – polyethylene film.
10 kg – polyethylene canisters (4) – polyethylene film.
20 kg – polyethylene canisters (4) – polyethylene film.

Marketing Authorization Holder

Moscow Pharmaceutical Factory CJS (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for external use 0.05%: bottle 100, 500, or 1000 ml

Dosage Form, Packaging, and Composition

Solution for external use 0.05% 100 ml
Chlorhexidine digluconate (in the form of a 20% solution) 50 mg

100 ml – polyethylene bottles.
500 ml – polyethylene bottles.
1000 ml – polyethylene bottles.

Marketing Authorization Holder

PharmVILAR NPO, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 25 ml, 50 ml or 100 ml bottle.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% in the form of a colorless, transparent or slightly opalescent liquid without odor.

1000 ml
20% chlorhexidine digluconate solution 2.5 ml
   Which corresponds to the content of chlorhexidine digluconate 500 mg

Excipients: purified water – up to 1000 ml.

25 ml – polymer dropper bottles (1) – cardboard packs.
50 ml – dark glass bottles (1) – cardboard packs.
50 ml – polymer dropper bottles (1) – cardboard packs.
50 ml – polyethylene terephthalate bottles (1) – cardboard packs.
100 ml – dark glass bottles (1) – cardboard packs.
100 ml – polymer dropper bottles (1) – cardboard packs.
100 ml – polyethylene terephthalate bottles (1) – cardboard packs.
200 ml – polymer dropper bottles (1) – cardboard packs.
1 L – polyethylene canisters (1) – group packaging (for hospitals).
3 L – polyethylene canisters (1) – group packaging (for hospitals).
5 L – polyethylene canisters (1) – group packaging (for hospitals).
10 L – polyethylene canisters (1) – group packaging (for hospitals).
20 L – polyethylene canisters (1) – group packaging (for hospitals).

Marketing Authorization Holder

Obnovlenie Pfc, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: dropper tubes 2 ml 5 or 10 pcs., 5 ml 5 pcs. or 10 ml 1, 2, 5, or 10 pcs. and dropper bottles 50 ml or 100 ml

Dosage Form, Packaging, and Composition

Solution for topical and external use colorless or light yellow, transparent or slightly opalescent, odorless.

1000 ml
Chlorhexidine bigluconate (substance-solution) 2.5 ml,
   Which corresponds to the content of chlorhexidine bigluconate 500 mg

Excipients: purified water – up to 1000 ml.

2 ml – dropper tubes (5) – cardboard packs.
2 ml – dropper tubes (10) – cardboard packs.
5 ml – dropper tubes (5) – cardboard packs.
10 ml – dropper tubes (1) – cardboard packs.
10 ml – dropper tubes (2) – cardboard packs.
10 ml – dropper tubes (5) – cardboard packs.
10 ml – dropper tubes (10) – cardboard packs.
50 ml – dropper bottles (1) – cardboard packs.
100 ml – dropper bottles (1) – cardboard packs.

Marketing Authorization Holder

Promomed Rus LLC (Russia)

Manufactured By

Biokhimik, JSC (Russia)

Dosage Forms

Bottle OTC Icon Chlorhexidine Vaginal suppositories 8 mg: 10 pcs.
Vaginal suppositories 16 mg: 10 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 20% solution 40 mg,
   Which corresponds to the content of chlorhexidine bigluconate 8 mg

Excipients: macrogol 1500 – 2337 mg, macrogol 400 – 123 mg.

5 pcs. – contour cell packs (2) – cardboard packs.


Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 20% solution 80 mg,
   Which corresponds to the content of chlorhexidine bigluconate 16 mg

Excipients: macrogol 1500 – 2299 mg, macrogol 400 – 121 mg.

5 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Rosbio, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for external use alcohol 0.5%: bottle 100 ml, 1, 3, 5, and 10 L

Dosage Form, Packaging, and Composition

Alcohol solution for external use 0.5% 100 ml
Chlorhexidine bigluconate 500 mg
(in the form of a 20% solution)

1 L – polymer bottles (for hospitals).
100 ml – dark glass bottles.
3 L – polyethylene canisters (for hospitals).
5 L – polyethylene canisters (for hospitals).
10 L – polyethylene canisters (for hospitals).

Marketing Authorization Holder

Rosbio, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine External use alcohol spray 0.5%: 70 ml or 100 ml bottle, vial

Dosage Form, Packaging, and Composition

Alcohol spray for external use 0.5% in the form of a colorless, transparent, slightly opalescent liquid with the smell of alcohol.

100 ml
Chlorhexidine bigluconate (in the form of a 20% solution) 500 mg

Excipients: ethanol 95% – 718.5 ml (583 g), purified water – up to 1000 ml (281 g).

70 ml – polyethylene bottles with a sprayer.
70 ml – bottles.
100 ml – polyethylene bottles with a sprayer.
100 ml – bottles.

Marketing Authorization Holder

Salvus, LLC (Russia)

Manufactured By

Rubicon, LLC (Republic of Belarus)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 5, 10, or 15 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface, the presence of an air rod and a funnel-shaped depression are allowed.

1 supp.
Chlorhexidine bigluconate, substance-solution 20% 80 mg,
   Which corresponds to the content of chlorhexidine bigluconate 16 mg

Excipients: macrogol 1500 – 2869 mg, macrogol 400 – 151 mg.

5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (3) – cardboard packs.

Marketing Authorization Holder

Tula Pharmaceutical Factory, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for external use, alcoholic 0.5%: 5 ml, 10 ml, 15 ml, 20 ml, 25 ml, 30 ml, 35 ml, 40 ml, 45 ml, 50 ml, 55 ml, 60 ml, 65 ml, 70 ml, 75 ml, 80 ml, 85 ml, 90 ml, 95 ml, or 100 ml bottle

Dosage Form, Packaging, and Composition

Alcohol solution for external use in the form of a colorless or light yellow, transparent or slightly opalescent liquid, with a characteristic odor.

1000 ml
Chlorhexidine bigluconate (20% solution for the preparation of dosage forms) 25 ml,
   Which corresponds to the content of chlorhexidine bigluconate 5 g

Excipients: ethyl alcohol 95% – 718.5 ml, purified water – up to 1000 ml.

5 ml – bottles (1) – cardboard packs.
10 ml – bottles (1) – cardboard packs.
15 ml – bottles (1) – cardboard packs.
20 ml – bottles (1) – cardboard packs.
25 ml – bottles (1) – cardboard packs.
30 ml – bottles (1) – cardboard packs.
35 ml – bottles (1) – cardboard packs.
40 ml – bottles (1) – cardboard packs.
45 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
55 ml – bottles (1) – cardboard packs.
60 ml – bottles (1) – cardboard packs.
65 ml – bottles (1) – cardboard packs.
70 ml – bottles (1) – cardboard packs.
75 ml – bottles (1) – cardboard packs.
80 ml – bottles (1) – cardboard packs.
85 ml – bottles (1) – cardboard packs.
90 ml – bottles (1) – cardboard packs.
95 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.

Marketing Authorization Holder

Tula Pharmaceutical Factory, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 14, 15, 16, 18, or 20 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 20% solution 85.2 mg,
   Which corresponds to the content of chlorhexidine bigluconate 16 mg

Excipients: macrogol-1500 (polyethylene glycol 1500) – 2533.3 mg, macrogol-400 (polyethylene glycol 400) – 225.2 mg, macrogol-4000 (polyethylene glycol 4000) – 56.3 mg.

1 pc. – contour cell packs (1) – cardboard packs.
1 pc. – contour cell packs (2) – cardboard packs.
1 pc. – contour cell packs (3) – cardboard packs.
1 pc. – contour cell packs (4) – cardboard packs.
1 pc. – contour cell packs (5) – cardboard packs.
1 pc. – contour cell packs (6) – cardboard packs.
1 pc. – contour cell packs (7) – cardboard packs.
1 pc. – contour cell packs (8) – cardboard packs.
1 pc. – contour cell packs (9) – cardboard packs.
1 pc. – contour cell packs (10) – cardboard packs.
2 pcs. – contour cell packs (1) – cardboard packs.
2 pcs. – contour cell packs (2) – cardboard packs.
2 pcs. – contour cell packs (3) – cardboard packs.
2 pcs. – contour cell packs (4) – cardboard packs.
2 pcs. – contour cell packs (5) – cardboard packs.
2 pcs. – contour cell packs (6) – cardboard packs.
2 pcs. – contour cell packs (7) – cardboard packs.
2 pcs. – contour cell packs (8) – cardboard packs.
2 pcs. – contour cell packs (9) – cardboard packs.
2 pcs. – contour cell packs (10) – cardboard packs.
3 pcs. – contour cell packs (1) – cardboard packs.
3 pcs. – contour cell packs (2) – cardboard packs.
3 pcs. – contour cell packs (3) – cardboard packs.
3 pcs. – contour cell packs (4) – cardboard packs.
3 pcs. – contour cell packs (5) – cardboard packs.
3 pcs. – contour cell packs (6) – cardboard packs.
4 pcs. – contour cell packs (1) – cardboard packs.
4 pcs. – contour cell packs (2) – cardboard packs.
4 pcs. – contour cell packs (3) – cardboard packs.
4 pcs. – contour cell packs (4) – cardboard packs.
4 pcs. – contour cell packs (5) – cardboard packs.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (3) – cardboard packs.
5 pcs. – contour cell packs (4) – cardboard packs.
6 pcs. – contour cell packs (1) – cardboard packs.
6 pcs. – contour cell packs (2) – cardboard packs.
6 pcs. – contour cell packs (3) – cardboard packs.
7 pcs. – contour cell packs (1) – cardboard packs.
7 pcs. – contour cell packs (2) – cardboard packs.
8 pcs. – contour cell packs (1) – cardboard packs.
8 pcs. – contour cell packs (2) – cardboard packs.
9 pcs. – contour cell packs (1) – cardboard packs.
9 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (1) – cardboard packs.
10 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: fl. 25 ml, 50 ml or 100 ml.

Dosage Form, Packaging, and Composition

Alcohol solution for external use colorless or light yellow, transparent or slightly opalescent, with a characteristic odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 25 ml

Excipients: ethanol (ethyl alcohol 95%) – 718.5 ml, purified water – up to 1000 ml.

25 ml – polyethylene bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.

Marketing Authorization Holder

Usolye-Sibirskiy Chemical and Pharmaceutical Plant, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 5, 10, 15, 20, 25, 30, 35, 40, 45, or 50 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 20% solution 85.2 mg,
   Which corresponds to the content of chlorhexidine bigluconate 16 mg

Excipients: macrogol 1500 (polyethylene glycol 1500) – 2533.3 mg, macrogol 400 (polyethylene glycol 400) – 225.2 mg, macrogol 4000 (polyethylene glycol 4000) – 56.3 mg.

Suppository weight – 2.9 g.

5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (3) – cardboard packs.
5 pcs. – contour cell packs (4) – cardboard packs.
5 pcs. – contour cell packs (5) – cardboard packs.
5 pcs. – contour cell packs (6) – cardboard packs.
5 pcs. – contour cell packs (7) – cardboard packs.
5 pcs. – contour cell packs (8) – cardboard packs.
5 pcs. – contour cell packs (9) – cardboard packs.
5 pcs. – contour cell packs (10) – cardboard packs.

Marketing Authorization Holder

Pharmanova, LLC (Russia)

Manufactured By

Biopharmkombinat, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Alcohol solution for external use 0.5%: fl. 25 ml, 50 ml or 100 ml.

Dosage Form, Packaging, and Composition

Alcohol solution for external use 0.5% a colorless, transparent or slightly opalescent liquid with a characteristic smell of alcohol.

1000 ml
Chlorhexidine bigluconate (20% solution) 25 ml
   Which corresponds to the content of chlorhexidine bigluconate 26.625 g

Excipients: ethanol 95% – 718.5 ml, purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
25 ml – polymer bottles with a dropper cap (70) – cardboard boxes (for hospitals).
50 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
50 ml – polymer bottles with a dropper cap (70) – cardboard boxes (for hospitals).
100 ml – polyethylene bottles (40) – cardboard boxes (for hospitals).
100 ml – polymer bottles with a dropper cap (40) – cardboard boxes (for hospitals).
500 ml – polymer bottles (12) – cardboard boxes (for hospitals).
1000 ml – polymer bottles (8) – cardboard boxes (for hospitals).
3 kg – polyethylene canisters (for hospitals).
5 kg – polyethylene canisters (for hospitals).
10 kg – polyethylene canisters (for hospitals).
20 kg – polyethylene bottles with a sprayer.

Marketing Authorization Holder

Pharmanova, LLC (Russia)

Manufactured By

Biopharmkombinat, LLC (Russia)

Dosage Forms

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: fl. 25 ml, 50 ml or 100 ml.
Solution for topical and external use 0.05%: fl. 25 ml, 50 ml or 100 ml.
Solution for topical and external use 0.5%: fl. 25 ml, 50 ml or 100 ml.
Solution for topical and external use 1%: fl. 25 ml, 50 ml or 100 ml.
Solution for topical and external use 2%: 25 ml, 50 ml, or 100 ml bottle.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.2% is colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 10 ml
   Which corresponds to the content of chlorhexidine bigluconate 2 g

Excipients: purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
50 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
100 ml – polyethylene bottles (40) – cardboard boxes (for hospitals).
500 ml – polymer bottles (12) – cardboard boxes (for hospitals).
1000 ml – polymer bottles (8) – cardboard boxes (for hospitals).
3 kg – polyethylene canisters (for hospitals).
5 kg – polyethylene canisters (for hospitals).
10 kg – polyethylene canisters (for hospitals).
20 kg – polyethylene canisters (for hospitals).


Solution for topical and external use 0.05% is colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 2.5 ml
   Which corresponds to the content of chlorhexidine bigluconate 500 mg

Excipients: purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
50 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
100 ml – polyethylene bottles (40) – cardboard boxes (for hospitals).
500 ml – polymer bottles (12) – cardboard boxes (for hospitals).
1000 ml – polymer bottles (8) – cardboard boxes (for hospitals).
3 kg – polyethylene canisters (for hospitals).
5 kg – polyethylene canisters (for hospitals).
10 kg – polyethylene canisters (for hospitals).
20 kg – polyethylene canisters (for hospitals).


Solution for topical and external use 0.5% is colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 25 ml
   Which corresponds to the content of chlorhexidine bigluconate 5 g

Excipients: purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
50 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
100 ml – polyethylene bottles (40) – cardboard boxes (for hospitals).
500 ml – polymer bottles (12) – cardboard boxes (for hospitals).
1000 ml – polymer bottles (8) – cardboard boxes (for hospitals).
3 kg – polyethylene canisters (for hospitals).
5 kg – polyethylene canisters (for hospitals).
10 kg – polyethylene canisters (for hospitals).
20 kg – polyethylene canisters (for hospitals).


Solution for topical and external use 1% is colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 50 ml
   Which corresponds to the content of chlorhexidine bigluconate 10 g

Excipients: purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
50 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
100 ml – polyethylene bottles (40) – cardboard boxes (for hospitals).
500 ml – polymer bottles (12) – cardboard boxes (for hospitals).
1000 ml – polymer bottles (8) – cardboard boxes (for hospitals).
3 kg – polyethylene canisters (for hospitals).
5 kg – polyethylene canisters (for hospitals).
10 kg – polyethylene canisters (for hospitals).
20 kg – polyethylene canisters (for hospitals).


Solution for topical and external use is colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 250 ml
   Which corresponds to the content of chlorhexidine bigluconate 50 g

Excipients: purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
50 ml – polyethylene bottles (70) – cardboard boxes (for hospitals).
100 ml – polyethylene bottles (40) – cardboard boxes (for hospitals).
500 ml – polymer bottles (12) – cardboard boxes (for hospitals).
1000 ml – polymer bottles (8) – cardboard boxes (for hospitals).
3 kg – polyethylene canisters (for hospitals).
5 kg – polyethylene canisters (for hospitals).
10 kg – polyethylene canisters (for hospitals).
20 kg – polyethylene canisters (for hospitals).

Marketing Authorization Holder

Pharmatoriya, LLC (Russia)

Manufactured By

Kemerovo Pharmaceutical Factory JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for external use 0.5%: bottles 50 ml, 70 ml or 100 ml; bottles 200 ml, 250 ml, 500 ml and 1 l; canisters 1 l, 3 l, 5 l, 10 l, 20 l

Dosage Form, Packaging, and Composition

Solution for external use is colorless or slightly yellowish, transparent or slightly opalescent, with a characteristic alcohol odor.

1000 ml
Chlorhexidine bigluconate (20% solution) 25 ml
   Which corresponds to the content of chlorhexidine bigluconate 5 g

Excipients: ethanol (ethyl alcohol 95%) – 718.5 ml, purified water – up to 1000 ml.

50 ml – dark glass bottles (1) – cardboard packs.
100 ml – dark glass bottles (1) – cardboard packs.
100 ml – dropper bottles (1) – cardboard packs.
100 ml – polyethylene terephthalate bottles (1) – cardboard packs.
50 ml – polyethylene bottles (1) – cardboard packs.
70 ml – polyethylene bottles (1) – cardboard packs.
100 ml – polyethylene bottles (1) – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
250 ml – polyethylene bottles (1) for hospitals – cardboard packs.
500 ml – polyethylene bottles (1) for hospitals – cardboard packs.
1 l – polyethylene bottles (1) for hospitals – cardboard packs.
1 l – polyethylene canisters (1) for hospitals – cardboard packs.
3 l – polyethylene canisters (1) for hospitals – cardboard packs.
5 l – polyethylene canisters (1) for hospitals – cardboard packs.
10 l – polyethylene canisters (1) for hospitals – cardboard packs.
20 l – polyethylene canisters (1) for hospitals – cardboard packs.

Marketing Authorization Holder

Pharmatoriya, LLC (Russia)

Manufactured By

Kirov Pharmaceutical Factory, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine External use alcohol spray 0.5%: 50 ml, 70 ml, or 100 ml bottle

Dosage Form, Packaging, and Composition

External use alcohol spray in the form of a colorless, transparent or slightly opalescent liquid with a characteristic alcohol odor.

1000 ml
Chlorhexidine bigluconate (in the form of a 20% solution substance) 5 g

Excipients: ethanol 95% (ethyl alcohol) – 718.5 ml, purified water – up to 1000 ml.

50 ml – polyethylene bottles with a spray (1) – cardboard boxes.
70 ml – polyethylene bottles with a spray (1) – cardboard boxes.
100 ml – polyethylene bottles with a spray (1) – cardboard boxes.
50 ml – dark glass bottles with a spraying device (1) – cardboard boxes.
70 ml – dark glass bottles with a spraying device (1) – cardboard boxes.
100 ml – dark glass bottles with a spraying device (1) – cardboard boxes.

Marketing Authorization Holder

Pharmaceutical Factory Of St. Petersburg, PJSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: bottle 25, 50, 70, 100, or 200 ml.

Dosage Form, Packaging, and Composition

Solution for topical and external use 0.05% 100 ml
Chlorhexidine bigluconate (in the form of a 20% solution) 50 mg

25 ml – bottles (1) – cardboard packs.
25 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.
50 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.
50 ml – bottles (1) – cardboard packs.
70 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.
100 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.
100 ml – dark glass jars (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
200 ml – polyethylene bottles (1) with a polymer nozzle – cardboard packs.

Marketing Authorization Holder

Pharmproekt, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 8 mg: 10 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories are white or white with a yellowish tint, torpedo-shaped. Marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 8 mg

Excipients: macrogol 1500 1311.7 mg, macrogol 400 116.6 mg, macrogol 4000 29.1 mg.

Suppository weight: 1.5 g.

5 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Pharmproekt, JSC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 10 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories are white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 16 mg

Excipients: macrogol 1500 2533.3 mg, macrogol 400 225.2 mg, macrogol 4000 56.3 mg.

Suppository weight 2.9 g.

5 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Firm VIPS-MED, LLC (Russia)

Manufactured By

Nesvizh Medical Products Plant OJSC (Republic Of Belarus)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.02%: 200 ml or 400 ml bottle

Dosage Form, Packaging, and Composition

Solution for topical and external use in the form of a colorless, transparent or slightly opalescent liquid.

1000 ml
Chlorhexidine bigluconate (20% solution) 1 ml,
   Which corresponds to the content of chlorhexidine bigluconate 0.2 g

Excipients: purified water – up to 1000 ml.

200 ml – bottles (1) – cardboard packs.
400 ml – bottles (1) – cardboard packs.

Marketing Authorization Holder

Formula-FR, LLC (Russia)

Manufactured By

Tula Pharmaceutical Factory, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Vaginal suppositories 16 mg: 4, 5, 6, 8, 10, or 12 pcs.

Dosage Form, Packaging, and Composition

Vaginal suppositories are white or white with a yellowish tint, torpedo-shaped; marbling of the surface is allowed.

1 supp.
Chlorhexidine bigluconate 20% solution 85.2 mg,
   Which corresponds to the content of chlorhexidine bigluconate 16 mg

Excipients: macrogol 1500 (polyethylene glycol 1500) – 2533.3 mg, macrogol 400 (polyethylene glycol 400) – 225.2 mg, macrogol 4000 (polyethylene glycol 4000) – 56.3 mg.

4 pcs. – contour cell packs (1) – cardboard packs.
4 pcs. – contour cell packs (2) – cardboard packs.
5 pcs. – contour cell packs (1) – cardboard packs.
5 pcs. – contour cell packs (2) – cardboard packs.
6 pcs. – contour cell packs (1) – cardboard packs.
6 pcs. – contour cell packs (2) – cardboard packs.

Marketing Authorization Holder

Mir Chemical and Pharmaceutical Concern, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: 100 ml or 200 ml bottles 1 or 28 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 100 ml
Chlorhexidine bigluconate 200 mg
(in the form of a 20% solution)

100 ml – glass bottles (1) – cardboard packs.
200 ml – glass bottles (1) – cardboard packs.
100 ml – glass bottles (28) – cardboard boxes.
200 ml – glass bottles (28) – cardboard boxes.

Marketing Authorization Holder

Mir Chemical and Pharmaceutical Concern, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.5%: 100 ml or 200 ml bottles 1 or 28 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 100 ml
Chlorhexidine digluconate 500 mg
(in the form of a 20% solution)

100 ml – glass bottles (1) – cardboard packs.
200 ml – glass bottles (1) – cardboard packs.
100 ml – glass bottles (28) – cardboard boxes.
200 ml – glass bottles (28) – cardboard boxes.

Marketing Authorization Holder

Mir Chemical and Pharmaceutical Concern, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 100 ml or 200 ml bottles 1 or 28 pcs.

Dosage Form, Packaging, and Composition

Solution for topical and external use 100 ml
Chlorhexidine digluconate 50 mg
(in the form of a 20% solution)

100 ml – glass bottles (1) – cardboard packs.
200 ml – glass bottles (1) – cardboard packs.
100 ml – glass bottles (28) – cardboard boxes.
200 ml – glass bottles (28) – cardboard boxes.

Marketing Authorization Holder

Ecolab, CJS (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.05%: 100 ml jars or bottles 1 pc.

Dosage Form, Packaging, and Composition

Solution for topical and external use 100 ml
Chlorhexidine digluconate (in the form of a 20% solution) 50 mg

100 ml – jars (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
1000 ml – bottles.
5 kg – canisters.

Marketing Authorization Holder

Ecotex, LLC (Russia)

Manufactured By

Biopharmkombinat, LLC (Russia)

Dosage Forms

Bottle OTC Icon Chlorhexidine Solution for topical and external use 0.2%: 25 ml, 50 ml, 100 ml, or 200 ml bottle; 200 ml, 250 ml, 500 ml, or 1000 ml bottle.
Solution for topical and external use 0.05%: 25 ml, 50 ml, 100 ml, or 200 ml bottle; 200 ml, 250 ml, 500 ml, or 1000 ml bottle.
Solution for topical and external use 0.5%: 25 ml, 50 ml, 100 ml, or 200 ml bottle; 200 ml, 250 ml, 500 ml, or 1000 ml bottle.
Solution for topical and external use 1%: 25 ml, 50 ml, 100 ml, or 200 ml bottle; 200 ml, 250 ml, 500 ml, or 1000 ml bottle.
Solution for topical and external use 5%: 25 ml, 50 ml, 100 ml, or 200 ml bottle; 200 ml, 250 ml, 500 ml, or 1000 ml bottle.

Dosage Form, Packaging, and Composition

Solution for topical and external use colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (20% sol.) 10 ml
   Which corresponds to the content of chlorhexidine digluconate 2 g

Excipients : purified water – up to 1000 ml.

25 ml – polymer bottles (1) with a dropper cap – cardboard packs.
50 ml – polymer bottles (1) with a dropper cap – cardboard packs.
100 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
250 ml – polyethylene bottles (1) – cardboard packs.
500 ml – polyethylene bottles (1) – cardboard packs.
1000 ml – polyethylene bottles (1) – cardboard packs.


Solution for topical and external use colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (20% sol.) 2.5 ml
   Which corresponds to the content of chlorhexidine digluconate 0.5 g

Excipients : purified water – up to 1000 ml.

25 ml – polymer bottles (1) with a dropper cap – cardboard packs.
50 ml – polymer bottles (1) with a dropper cap – cardboard packs.
100 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
250 ml – polyethylene bottles (1) – cardboard packs.
500 ml – polyethylene bottles (1) – cardboard packs.
1000 ml – polyethylene bottles (1) – cardboard packs.


Solution for topical and external use colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (20% sol.) 25 ml
   Which corresponds to the content of chlorhexidine digluconate 5 g

Excipients : purified water – up to 1000 ml.

25 ml – polymer bottles (1) with a dropper cap – cardboard packs.
50 ml – polymer bottles (1) with a dropper cap – cardboard packs.
100 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
250 ml – polyethylene bottles (1) – cardboard packs.
500 ml – polyethylene bottles (1) – cardboard packs.
1000 ml – polyethylene bottles (1) – cardboard packs.


Solution for topical and external use colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (20% sol.) 50 ml
   Which corresponds to the content of chlorhexidine digluconate 10 g

Excipients : purified water – up to 1000 ml.

25 ml – polymer bottles (1) with a dropper cap – cardboard packs.
50 ml – polymer bottles (1) with a dropper cap – cardboard packs.
100 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
250 ml – polyethylene bottles (1) – cardboard packs.
500 ml – polyethylene bottles (1) – cardboard packs.
1000 ml – polyethylene bottles (1) – cardboard packs.


Solution for topical and external use colorless or light yellow, transparent, odorless or with a faint odor.

1000 ml
Chlorhexidine digluconate (20% sol.) 250 ml
   Which corresponds to the content of chlorhexidine digluconate 50 g

Excipients : purified water – up to 1000 ml.

25 ml – polymer bottles (1) with a dropper cap – cardboard packs.
50 ml – polymer bottles (1) with a dropper cap – cardboard packs.
100 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polymer bottles (1) with a dropper cap – cardboard packs.
200 ml – polyethylene bottles (1) – cardboard packs.
250 ml – polyethylene bottles (1) – cardboard packs.
500 ml – polyethylene bottles (1) – cardboard packs.
1000 ml – polyethylene bottles (1) – cardboard packs.

Marketing Authorization Holder

YUGPHARM, LLC (Russia)

Dosage Form

Bottle OTC Icon Chlorhexidine Solution for external use (alcoholic) 0.5%: 25 ml, 50 ml, 100 ml, 500 ml or 1000 ml bottle.

Dosage Form, Packaging, and Composition

Solution for external use in the form of a colorless or light yellow, transparent or slightly opalescent liquid, with a characteristic alcohol odor.

1 bottle
Chlorhexidine digluconate (20% sol.) 25 ml

Excipients : ethanol (ethyl alcohol 95%) – 718.5 ml, purified water – up to 1000 ml.

25 ml – bottles (1) – cardboard packs.
50 ml – bottles (1) – cardboard packs.
100 ml – bottles (1) – cardboard packs.
500 ml – bottles (1) – cardboard packs.
1000 ml – bottles (1) – cardboard packs.
1 l – polyethylene canisters (for hospitals).
3 l – polyethylene canisters (for hospitals).
5 l – polyethylene canisters (for hospitals).
10 l – polyethylene canisters (for hospitals).
20 l – polyethylene canisters (for hospitals).
21.5 l – polyethylene canisters (for hospitals).

Table of Contents

TABLE OF CONTENTS