Chlorophyllipt® (Tablets, Solution) Instructions for Use
ATC Code
D06BX (Other chemotherapeutic preparations for topical use)
Active Substance
Eucalypti folium (DAB German Pharmacopoeia)
Clinical-Pharmacological Group
Herbal preparation with antimicrobial action
Pharmacotherapeutic Group
Antimicrobial agent of plant origin
Pharmacological Action
A preparation of plant origin. Aqueous and alcoholic extracts from eucalyptus leaves exhibit bactericidal, antiviral, fungicidal, antiprotozoal, and anti-inflammatory effects. The degree of their severity depends on the content of essential oil (0.3-4.5%).
The activity of the main component of the essential oil, cineole (65-85%), is potentiated by pinenes, myrtenol, and tannins (up to 6%). When taken orally and in inhalations, eucalyptus preparations cause expectorant, mucolytic, and bronchodilator effects, and when applied to the skin – astringent, anti-exudative, antipruritic, anesthetic, and in higher concentrations, local irritant action. The infusion of eucalyptus leaves, due to the essential oil and a small amount of bitters, increases the secretion of the digestive glands and improves digestion. When used in the form of a tincture, a sedative effect is manifested, due to the aldehyde of isovaleric acid.
Chlorophyllipt®, containing a mixture of chlorophylls from eucalyptus leaves, possesses antimicrobial, particularly antistaphylococcal, activity and stimulates regeneration processes. The components of the essential oil, together with organic acids, tannins, and trace elements manganese, zinc, and selenium, increase tissue resistance to hypoxia of various origins.
Indications
As part of combination therapy for acute and chronic infectious and inflammatory diseases of various localization: rhinitis, stomatitis, gingivitis, laryngitis, bronchitis, pneumonia, hyposecretory gastritis, enterocolitis, dysbacteriosis, cholecystitis, pyelonephritis, vaginitis, colpitis, cervical erosion, burns, dermatitis, radiculitis, neuritis, myositis, trophic ulcers, neurosis, mild form of insomnia, osteochondrosis.
ICD codes
| ICD-10 code | Indication |
| F48.0 | Neurasthenia |
| F51.0 | Nonorganic insomnia |
| J00 | Acute nasopharyngitis (common cold) |
| J02 | Acute pharyngitis |
| J03 | Acute tonsillitis |
| J04 | Acute laryngitis and tracheitis |
| J15 | Bacterial pneumonia, not elsewhere classified |
| J20 | Acute bronchitis |
| J31.0 | Chronic rhinitis (including ozaena, atrophic and hypertrophic rhinitis) |
| J31.2 | Chronic pharyngitis |
| J35.0 | Chronic tonsillitis |
| J37 | Chronic laryngitis and laryngotracheitis |
| J42 | Unspecified chronic bronchitis |
| K05 | Gingivitis and periodontal diseases |
| K12 | Stomatitis and related lesions |
| K29 | Gastritis and duodenitis |
| K52.9 | Noninfective gastroenteritis and colitis, unspecified |
| K63.8 | Other specified diseases of intestine |
| K81.0 | Acute cholecystitis |
| K81.1 | Chronic cholecystitis |
| L30.9 | Dermatitis, unspecified |
| L98.4 | Chronic skin ulcer, not elsewhere classified |
| M42 | Spinal osteochondrosis |
| M54.1 | Radiculopathy |
| M54.3 | Sciatica |
| M54.4 | Lumbago with sciatica |
| M60 | Myositis |
| M79.2 | Neuralgia and neuritis, unspecified |
| N10 | Acute tubulointerstitial nephritis (acute pyelonephritis) |
| N11 | Chronic tubulointerstitial nephritis (chronic pyelonephritis) |
| N76 | Other inflammatory diseases of vagina and vulva |
| N86 | Erosion and ectropion of cervix |
| T30 | Burns and corrosions of unspecified body region |
| ICD-11 code | Indication |
| 6A8Z | Affective disorders, unspecified |
| 7A00 | Chronic insomnia |
| 7A01 | Acute insomnia |
| 7A0Z | Insomnia disorders, unspecified |
| 8B93.Z | Radiculopathy, unspecified |
| 8E4A.1 | Paraneoplastic or autoimmune diseases of the peripheral or autonomic nervous system |
| CA00 | Acute nasopharyngitis |
| CA02.Z | Acute pharyngitis, unspecified |
| CA03.Z | Acute tonsillitis, unspecified |
| CA05 | Acute laryngitis or tracheitis |
| CA09.0 | Chronic rhinitis |
| CA09.2 | Chronic pharyngitis |
| CA0F.Y | Other specified chronic diseases of the palatine tonsils and adenoids |
| CA0G | Chronic laryngitis or laryngotracheitis |
| CA20.1Z | Chronic bronchitis, unspecified |
| CA40.0Z | Bacterial pneumonia, unspecified |
| CA42.Z | Acute bronchitis, unspecified |
| DA01.Z | Diseases of the oral mucosa, unspecified |
| DA0B.Z | Gingival diseases, unspecified |
| DA0C.Z | Periodontal diseases, unspecified |
| DA0Z | Diseases or disorders of the orofacial complex, unspecified |
| DA42.Z | Gastritis, unspecified |
| DA51.Z | Duodenitis, unspecified |
| DA7Z | Diseases of stomach or duodenum, unspecified |
| DA90.0 | Syndromic diarrhea |
| DA92.1 | Pneumatosis intestinalis of the small intestine |
| DA98.Z | Polyps of small intestine, unspecified |
| DB31.1 | Pneumatosis of the colon |
| DB36.Z | Certain infections of the colon, unspecified |
| DC12.0Z | Acute cholecystitis, unspecified |
| DC12.1 | Chronic cholecystitis |
| DE2Z | Diseases of the digestive system, unspecified |
| EA40 | Tropical phagedenic ulcer |
| EA85.2Z | Hand dermatitis, unspecified |
| EA85.3 | Foot dermatitis |
| EA89 | Generalized eczematous dermatitis of unspecified type |
| EA8Z | Dermatitis or eczema, unspecified |
| EF60 | Ischemic ulceration of the skin |
| EM0Z | Unspecified skin disorder |
| FA85.Z | Defects of vertebral end-plates, unspecified |
| FB30 | Infectious myositis |
| FB32 | Other specified disorders of muscle |
| FB3Z | Disorder of muscle, unspecified |
| FB56 | Specified soft tissue diseases, not elsewhere classified |
| FB56.0 | Granuloma of soft tissue due to foreign body, not elsewhere classified |
| GA00 | Vulvitis |
| GA02.Z | Unspecified vaginitis |
| GA0Z | Inflammatory diseases of female genital tract, unspecified |
| GA15.1 | Erosion or ectropion of cervix |
| GB50 | Acute tubulo-interstitial nephritis |
| GB51 | Acute pyelonephritis |
| GB55.Z | Chronic tubulo-interstitial nephritis, unspecified |
| GB5Z | Renal tubulo-interstitial diseases, unspecified |
| ME60.2 | Ulcerative skin lesion of unspecified nature |
| ME84.20 | Lumbago with sciatica |
| ME84.3 | Sciatica |
| NE11 | Burn of unspecified body region |
Dosage Regimen
| The method of application and dosage regimen for a specific drug depend on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly adhere to the compliance of the dosage form of a specific drug with the indications for use and dosage regimen. |
Administer orally, topically, externally, by inhalation, or via intracavitary routes based on the specific clinical indication and the pharmaceutical form utilized.
For oral administration of tablets, adhere to the specific product information; typically, use one tablet for oromucosal dissolution several times daily.
For gargling, dilute a 1% alcoholic solution: use 5 ml (approximately one teaspoon) in 30 ml of water.
For intracavitary administration, such as vaginal irrigation or cervical treatment, dilute a 1% solution: use 15 ml in one liter of water.
For enemas, dilute a 1% solution: use 20 ml in one liter of water.
For inhalation therapy, dilute a 1% alcoholic solution: use 1 ml per 10 ml of physiological sodium chloride solution.
For external application on wounds, ulcers, or burns, apply a 2% oil-based solution directly to the affected area.
For internal use of the solution, dilute 5 ml (one teaspoon) of a 1% alcoholic solution in 30 ml of water; administer this three times daily.
Adjust the dose, frequency, and treatment duration individually according to the diagnosed condition, severity, and patient age.
Before initiating a full course, mandatorily perform a sensitivity test by administering 25 drops of a 1% alcoholic solution in one tablespoon of water; observe for 6-8 hours for any allergic manifestations.
Adverse Reactions
Possible allergic reactions to the components of the essential oil and chlorophyllipt; when taken orally in high doses – nausea, vomiting, diarrhea, muscle spasms; with frequent and/or prolonged inhalation use – dryness of the mucous membranes of the respiratory tract.
Contraindications
Hypersensitivity to the components of the essential oil and chlorophyllipt; atrophy of the mucous membranes of the upper respiratory tract.
Use in Pregnancy and Lactation
The use of eucalyptus leaf preparations containing ethyl alcohol is contraindicated during pregnancy and breastfeeding.
Pediatric Use
The use of eucalyptus leaf preparations containing ethyl alcohol is contraindicated in children and adolescents under 18 years of age.
Special Precautions
Use with caution in cases of increased secretion of the digestive glands.
Avoid contact of eucalyptus preparations (especially tincture, eucalyptus oil, chlorophyllipt) with the eyes.
Before starting treatment, it is necessary to check the patient’s sensitivity to the plant. For this, the patient is given a tablespoon of infusion, 10 drops of tincture, or 25 drops of a 1% alcoholic solution of chlorophyllipt in 1 tablespoon of water to drink. If no allergic reactions occur within 6-8 hours, a course of treatment can be prescribed. A negative attitude of the patient towards the smell of eucalyptus may indicate intolerance.
Storage Conditions
Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.
Dispensing Status
Over-the-Counter
Important Safety Information
This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.
Medical DisclaimerBrand (or Active Substance), Marketing Authorisation Holder, Dosage Form
Alcoholic 1% solution for oral and external use: 100 mL bottle
Marketing Authorization Holder
Pharmaceutical Balkans, d.o.o. (Serbia)
Dosage Form
| Chlorophyllipt® | Alcoholic 1% solution for oral and external use: 100 mL bottle |
Dosage Form, Packaging, and Composition
| Alcoholic 1% solution for oral and external use | 1 ml |
| Chlorophyllipt thick extract (extract of Eucalyptus globulus leaves with a content of the sum of chlorophylls not less than 10%) | 10 mg |
100 ml – dark glass bottles (1) – cardboard packs.
Alcohol solution for oral, topical, and external use 1%: bottle 25 ml or 50 ml
Marketing Authorization Holder
Art-Pharm, LLC (Russia)
Manufactured By
Kirov Pharmaceutical Factory, JSC (Russia)
Dosage Form
| Chlorophyllipt® | Alcohol solution for oral, topical, and external use 1%: bottle 25 ml or 50 ml |
Dosage Form, Packaging, and Composition
Alcoholic solution for oral, topical, and external use dark green in color, with a characteristic odor; during storage, precipitation is allowed, forming a coating on the walls and bottom of the bottle.
| 1 ml | |
| Chlorophyllipt thick extract (calculated on dry substance)* | 10 mg |
* chlorophyllipt – a mixture of chlorophylls obtained from eucalyptus leaves.
Excipients : ethanol (ethyl alcohol) 96% – up to 1 ml.
25 ml – dark glass bottles (1) – cardboard packs.
50 ml – dark glass bottles (1) – cardboard packs.
Oil solution for topical application 2%: bottle 20 ml or 30 ml
Marketing Authorization Holder
Vifitech, CJSC (Russia)
Dosage Form
| Chlorophyllipt® | Oil solution for topical application 2%: bottle 20 ml or 30 ml |
Dosage Form, Packaging, and Composition
| Oil solution for topical application 2% | 100 ml |
| Extract of Eucalyptus globulus leaves | 2 g |
20 ml – dark glass bottles (1) – cardboard packs.
30 ml – dark glass bottles (1) – cardboard packs.
Sublingual tablets 25 mg: 20, 30 or 50 pcs.
Marketing Authorization Holder
Vifitech, CJSC (Russia)
Dosage Form
| Chlorophyllipt® | Sublingual tablets 25 mg: 20, 30 or 50 pcs. |
Dosage Form, Packaging, and Composition
Sublingual tablets from light green to green in color with lighter and darker inclusions, flat-cylindrical, with a bevel and a score and a characteristic odor.
| 1 tab. | |
| Chlorophyllipt (thick extract of Eucalyptus globulus leaves) | 25 mg |
Excipients : sugar (sucrose) – 617 mg, microcrystalline cellulose – 120 mg, citric acid monohydrate – 30 mg, calcium stearate – 8 mg.
10 pcs. – contour cell packs (2) – cardboard packs.
10 pcs. – contour cell packs (3) – cardboard packs.
10 pcs. – contour cell packs (5) – cardboard packs.
Alcohol solution for oral and topical administration 1%: bottle 25 ml, 50 ml, or 100 ml
Marketing Authorization Holder
Vifitech, CJSC (Russia)
Dosage Form
| Chlorophyllipt® | Alcohol solution for oral and topical administration 1%: bottle 25 ml, 50 ml, or 100 ml |
Dosage Form, Packaging, and Composition
| Alcoholic 1% solution for oral and topical administration | 1 ml |
| Chlorophyllipt thick extract (with antibacterial activity at a concentration of 12.5 mcg in 1 ml of medium) | 10 mg |
25 ml – dark glass bottles (1) – cardboard packs.
50 ml – dark glass bottles (1) – cardboard packs.
100 ml – dark glass bottles (1) – cardboard packs.
Oil solution for topical application 2%: bottle 20 ml
Marketing Authorization Holder
Experimental Plant Of The Ssc Ls Of The Ukrmedprom Association, SC (Ukraine)
Dosage Form
| Chlorophyllipt® | Oil solution for topical application 2%: bottle 20 ml |
Dosage Form, Packaging, and Composition
| Oil solution for topical application 2% | 20 ml |
| Chlorophyllipt thick extract (calculated on 100% content of dry substance) | 400 mg |
20 ml – dark glass bottles (1) – cardboard packs.
