Chlorophyllong^® (Solution) Instructions for Use

Marketing Authorization Holder

Tula Pharmaceutical Factory, LLC (Russia)

Manufactured By

Tula Pharmaceutical Factory, LLC (Russia)

Or

Pharmaceutical Factory Of St. Petersburg, PJSC (Russia)

ATC Codes

D06BX (Other chemotherapeutic preparations for topical use)

G01AX (Other antimicrobials and antiseptics)

Active Substance

Eucalypti folium (DAB German Pharmacopoeia)

Dosage Form

Chlorophyllong®

Alcohol solution for oral and topical administration: bottle 25 ml, 50 ml, or 100 ml

Dosage Form, Packaging, and Composition

Alcohol solution for oral and topical administration in the form of a transparent liquid from green to dark green in color, with a characteristic odor; cloudiness of the liquid and precipitation may occur during storage.

Excipients: copper chloride dihydrate (copper chloride dihydrate) – 0.06 g, ethanol 95% – up to 1000 ml.

25 ml – bottles* (1) – cardboard packs.
50 ml – bottles* (1) – cardboard packs.
100 ml – bottles* (1) – cardboard packs.

* supplied with or without a dosing spoon, or a measuring cup, or a dosing syringe.

Clinical-Pharmacological Group

Herbal preparation with antimicrobial and anti-inflammatory action

Pharmacotherapeutic Group

Antimicrobial agent of plant origin

Pharmacological Action

Herbal remedy. Aqueous and alcoholic extracts from eucalyptus leaves exhibit bactericidal, antiviral, fungicidal, antiprotozoal, and anti-inflammatory effects. The degree of their severity depends on the content of essential oil (0.3-4.5%).

The activity of the main component of the essential oil, cineole (65-85%), is potentiated by pinenes, myrtenol, and tannins (up to 6%). When taken orally and in inhalations, eucalyptus preparations cause expectorant, mucolytic, and bronchodilatory effects, and when applied to the skin, an astringent, anti-exudative, antipruritic, anesthetic, and at higher concentrations, a locally irritating effect. The infusion of eucalyptus leaves, due to the essential oil and a small amount of bitters, increases the secretion of the digestive glands and improves digestion. When used in the form of a tincture, a sedative effect is manifested, due to the aldehyde of isovaleric acid.

Chlorophyllipt, containing a mixture of chlorophylls from eucalyptus leaves, has antimicrobial, especially antistaphylococcal, activity and stimulates regeneration processes. The components of the essential oil, together with organic acids, tannins, and trace elements manganese, zinc, and selenium, increase tissue resistance to hypoxia of various origins.

Indications

As part of combination therapy for acute and chronic infectious and inflammatory diseases of various localization: rhinitis, stomatitis, gingivitis, laryngitis, bronchitis, pneumonia, hyposecretory gastritis, enterocolitis, dysbacteriosis, cholecystitis, pyelonephritis, vaginitis, colpitis, cervical erosion, burns, dermatitis, radiculitis, neuritis, myositis, trophic ulcers, neurosis, mild form of insomnia, osteochondrosis.

ICD codes

Dosage Regimen

Use the solution orally, topically, externally, by inhalation, or for intracavitary administration.

For oral administration, dilute 5 ml of the solution in 30 ml of water. Take this dose three times daily.

For topical use in otorhinolaryngology, prepare a 1% solution by diluting 1 part of the concentrate in 100 parts of purified water. Use for gargling, nasal instillation, or irrigation.

For treating skin conditions such as trophic ulcers or burns, apply a 2% solution topically using moistened gauze dressings.

For intracavitary use in gynecology, for conditions like colpitis or cervical erosion, administer a 1% solution via tamponade or douching.

For inhalation therapy in respiratory diseases, add 1 ml of the solution to an inhaler. Perform the procedure for 5-10 minutes.

Always perform a sensitivity test before initiating treatment. Administer 25 drops of a 1% alcohol solution in a tablespoon of water. Observe for 6-8 hours for any allergic reactions.

The specific dosage, frequency, and treatment duration must be determined individually by a physician based on the indication and patient response.

Adverse Reactions

Possible allergic reactions to the components of the essential oil and chlorophyllipt; when taken orally in high doses – nausea, vomiting, diarrhea, muscle spasms; with frequent and/or prolonged inhalation use – dryness of the mucous membranes of the respiratory tract.

Contraindications

Hypersensitivity to the components of the essential oil and chlorophyllipt; atrophy of the mucous membranes of the upper respiratory tract.

Use in Pregnancy and Lactation

The use of eucalyptus leaf preparations containing ethyl alcohol is contraindicated during pregnancy and breastfeeding.

Pediatric Use

The use of eucalyptus leaf preparations containing ethyl alcohol is contraindicated in children and adolescents under 18 years of age.

Special Precautions

Use with caution in cases of increased secretion of the digestive glands.

Avoid contact of eucalyptus preparations (especially tincture, eucalyptus oil, chlorophyllipt) with the eyes.

Before starting treatment, it is necessary to check the patient’s sensitivity to the plant. For this, the patient is given a tablespoon of the infusion, 10 drops of the tincture, or 25 drops of a 1% alcohol solution of chlorophyllipt in 1 tablespoon of water to drink. If no allergic reactions occur within 6-8 hours, a course of treatment can be prescribed. A negative attitude of the patient towards the smell of eucalyptus may indicate intolerance.

Storage Conditions

Store at 2°C (36°F) to 25°C (77°F). Keep in original packaging, protected from light. Keep out of reach of children.

Dispensing Status

Over-the-Counter

Important Safety Information

This information is for educational purposes only and does not replace professional medical advice. Always consult your doctor before use. Dosage and side effects may vary. Use only as prescribed.